Hypopigmented Skin: Causes & Reasons

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Possible Causes for Hypopigmented Skin

Tuberous Sclerosis

Clinical findings Range from benign hypopigmented skin macules, to profound mental retardation with intractable seizures and premature death due to disease-associated causes [medical-dictionary.thefreedictionary.com]

He additionally had two hypopigmented lesions on the skin. He underwent resection of the left parietal lobe 32months after seizure onset. [ncbi.nlm.nih.gov]

TSC is a generic disorder characterized by abnormal skin pigmentations (hypopigmented macules, shagreen patches) and tumor formation in multiple organ systems (brain, heart [med.uth.edu]

Vitiligo

Vitiligo-like lesions, defined as hypopigmented skin lesions, have already been associated with the use of ICIs in particular in patients with malignant melanoma, probably [ncbi.nlm.nih.gov]

since reduced tanning of normal skin will decrease the contrast with hypopigmented skin.[4] Most patients with nevus depigmentosus do not pursue treatment for their lesion [en.wikipedia.org]

Examination with Wood's lamp is often helpful to see the hypopigmented skin lesions of this condition. Mild to moderate growth restriction is common. [patient.info]

Phenylketonuria

Four additional cases of PKU diagnosed were siblings of screening detected cases who all presented with mental retardation, microcephaly, hypopigmented hair and skin and seizures [ncbi.nlm.nih.gov]

Toxic Liver Disease

A study concluded the presence of toxic algae could put residents at a higher risk of fatal liver diseases. The study's authors said a direct tie has not yet been found, and they'd need to perform a separate study for that. Residents who live near large blue-green algae blooms are at a higher risk to develop[…] [weather.com]

Hyperphenylalaninemia

Homepage Rare diseases Search Search for a rare disease Hyperphenylalaninemia due to tetrahydrobiopterin deficiency Disease definition Hyperphenylalaninemia (HPA) due to tetrahydrobiopterin (BH4) deficiency, also known as malignant HPA is an amino acid disorder with neonatal onset that is clinically characterized by[…] [orpha.net]

Prader-Willi Syndrome

We report on a 4-year-old male with an interstitial tandem duplication of Xq21.1-q21.31 who presented with clinical features of Prader-Willi syndrome (PWS). The duplication was maternally inherited. Abnormalities of the X chromosome have previously been reported in association with a PWS phenotype, but to date, specific[…] [ncbi.nlm.nih.gov]

Extensive Burns

Burns. 1994;20 Suppl 1:S14-7; discussion S17-8. Author information 1 Rode Kruis Ziekenhuis, Anaesthesiology Department, Beverwijk, The Netherlands. Abstract Following the introduction in 1988 of a regimen of selective decontamination of the digestive tract (SDD) for extensively injured patients in our burns centre,[…] [ncbi.nlm.nih.gov]

Cartilage Hair Hypoplasia

Abstract Cartilage-hair hypoplasia (CHH) is an autosomal recessive skeletal dysplasia of unknown pathogenesis leading to short-limbed stature. Associated features include hypoplasia of hair, abnormal cellular immunity, deficient erythrogenesis, increased risk of malignancies, Hirschsprung disease, and Diamond-Blackfan[…] [doi.org]

Piebaldism

Patches of hypopigmented skin and hair in these disorders represent regions lacking in melanocytes, the result of defective melanoblast differentiation, migration, proliferation [ncbi.nlm.nih.gov]

[…] of hypopigmented and depigmented skin areas (leukoderma) on various parts of the body, preferentially on the forehead, chest, abdomen, upper arms, and lower extremities, [orpha.net]

skin patches Patchy loss of skin color 0001053 Macule Flat, discolored area of skin 0012733 White eyebrow Pale eyebrow 0002226 White eyelashes Blonde eyelashes Pale eyelashes [rarediseases.info.nih.gov]

Dyschromatosis Universalis Hereditaria Type 1

skin patches and hyperpigmented/hypopigmented macules. [selfdecode.com]

Additionally, many immature melanosomes were observed in hypopigmented skin region. [journals.plos.org]

Abstract Dyschromatosis is a pigmentary genodermatosis which presents with hyper and hypopigmented skin lesions giving a mottled appearance. [e-ijd.org]

Dyschromatosis Symmetrica Hereditaria

(d) In the hypopigmented skin, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Dermatology Wiley http://www.deepdyve.com/lp/wiley/ultrastructural-study-of-dyschromatosis-symmetrica-hereditaria-with-mmu1SSryNV [deepdyve.com]

Hyperpigmented hair was also found in normal and hypopigmented skin. The colors of the hair and the skin did not correlate. [ncbi.nlm.nih.gov]

skin patches and hyperpigmented/hypopigmented macules. [selfdecode.com]

Pityriasis Alba

Pityriasis alba is a common skin disorder of patches of light-colored (hypopigmented) areas. The cause is unknown but may be linked to atopic dermatitis (eczema). [nlm.nih.gov]

Preceded by erythematous changes, patches of hypopigmented skin of up to a few centimeters in diameter appear on the upper body. Pruritus may accompany it. [ncbi.nlm.nih.gov]

It is more noticeable in children with dark skin. Definition Pityriasis alba is a common skin disorder of patches of light-colored (hypopigmented) areas. [account.allinahealth.org]

Incontinentia Pigmenti Achromians

[…] derived from a hypopigmented skin area of M.B., with a slowly decreasing tetraploidy rate in the course of passaging: #2 23%, #5 11%, #11 and #14 6% and #18 and #21 2%. [ncbi.nlm.nih.gov]

We studied a boy with macrocephaly, hypotonia, pigmentary retinopathy, unilateral whorled hypopigmented skin lesions, and seizures. [ncbi.nlm.nih.gov]

Hypomelanosis of Ito (HMI) is a very rare birth defect that causes unusual patches of light-colored ( hypopigmented ) skin and may be associated with eye, nervous system, [nlm.nih.gov]

Tinea Versicolor

Hyperpigmented skin had thicker stratum corneum than hypopigmented but both were thicker than the uninvolved skin. [ncbi.nlm.nih.gov]

The hyperpigmented skin showed the stratum corneum to be leaner than in the hypopigmented skin, but in both the stratum corneum was thinner than in non-affected skin. [scielo.br]

Abstract A comparative histopathologic study is made between the hypopigmented and hyperpigmented skin lesions of pityriasis versicolor and normal skin areas utilizing histochemical [ncbi.nlm.nih.gov]

Klein-Waardenburg Syndrome

Hypopigmented skin patches are sometimes present but not all patients have them. Genetics The uniqueness of Waardenburg syndrome types 1 and 3 remains to be established. [disorders.eyes.arizona.edu]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome ? [dermnetnz.org]

Individuals with type 1 often have a white forelock (29%), premature graying (44%), and hypopigmented skin patches (55%). A few patients have cleft palate and/or lip. [disorders.eyes.arizona.edu]

Acromelanosis

Light microscopic findings of hyper- and hypopigmented skin were similar to those of normal skin, except that background staining of keratinocytes in dark and light macules [findzebra.com]

Abstract Dyschromatosis is a pigmentary genodermatosis which presents with hyper and hypopigmented skin lesions giving a mottled appearance. [e-ijd.org]

There was no atrophy of skin or loss of epidermal ridges over the lesions. There were no similar lesions elsewhere on the body. [ijdvl.com]

Dyschromatosis Universalis Hereditaria

Additionally, many immature melanosomes were observed in hypopigmented skin region. [journals.plos.org]

Abstract Dyschromatosis is a pigmentary genodermatosis which presents with hyper and hypopigmented skin lesions giving a mottled appearance. [e-ijd.org]

DUH is characterized by mixtures of hyperpigmented- and hypopigmented macules all over the body. Skin lesions are usually present in the first years of life. [sparrho.com]

Ermine Phenotype

Affiliated tissues include skin, and related phenotypes are sensorineural hearing impairment and hypopigmented skin patches [malacards.org]

Showing of 22 | 80%-99% of people have these symptoms Hypopigmentation of hair Loss of hair color 0005599 Hypopigmented skin patches Patchy loss of skin color 0001053 Sensorineural [rarediseases.info.nih.gov]

Borderline Leprosy

skin patches. [casereports.bmj.com]

There are various forms whose descriptions differ among two different classification systems, but the three cardinal clinical manifestations of leprosy are hypopigmented skin [amboss.com]

skin macules and anaesthetic patches, where skin sensations are lost because of damaged peripheral nerves that have been attacked by the host's immune cells. [wikidoc.org]

Microcephalic Osteodysplastic Primordial Dwarfism Type II

0000958 Full cheeks Apple cheeks Big cheeks Increased size of cheeks Large cheeks [ more ] 0000293 Hypopigmented skin patches Patchy loss of skin color 0001053 Joint hyperflexibility [rarediseases.info.nih.gov]

[…] female external genitalia Abnormal female external genitalia 0000055 Aplasia/Hypoplasia of the eyebrow Absence of eyebrow Lack of eyebrow Missing eyebrow [ more ] 0100840 Dry skin [rarediseases.info.nih.gov]

Oculocutaneous Albinism

OCA connotes a group of disorders that result in hypopigmented skin due to decreased melanin production in melanocytes and loss of visual acuity. [ncbi.nlm.nih.gov]

Oculocutaneous albinism (OCA) is a rare genetic disorder of melanin synthesis that results in hypopigmented hair, skin, and eyes. [ncbi.nlm.nih.gov]

Abstract Oculocutaneous albinism (OCA) is a set of autosomal recessive disorders characterized by hypopigmented hair, skin and eyes. [ncbi.nlm.nih.gov]

Limited Cutaneous Systemic Scleroderma

In the hypopigmented skin, multiple microscopic sections were devoid of melanocytes, with no melanin in adjacent basal cells. [ncbi.nlm.nih.gov]

skin patches Patchy loss of skin color 0001053 Narrow foramen obturatorium 0100958 30%-79% of people have these symptoms Dysphagia Poor swallowing Swallowing difficulties [rarediseases.info.nih.gov]

Showing of 13 | Medical Terms Other Names Learn More: HPO ID 80%-99% of people have these symptoms Autoimmunity Autoimmune disease Autoimmune disorder [ more ] 0002960 Hypopigmented [rarediseases.info.nih.gov]

Schimmelpenning-Feuerstein-Mims Syndrome

Mirizzi Syndrome

To view the fulltext, please log in To view the pdf, please log in Buy FullText & PDF Unlimited re-access via MyKarger Unrestricted printing, no saving restrictions for personal use read more CHF 38.00 * EUR 35.00 * USD 39.00 * Select KAB Buy a Karger Article Bundle (KAB) and profit from a discount ! If you would[…] [karger.com]

Cholangiocarcinoma

Bile duct cancer is a rare malignancy that calls for a strong multidisciplinary approach to treatment. Physician specialists at Froedtert & the Medical College of Wisconsin treat many patients with bile duct tumors every year, and they are familiar with the subtleties of this unusual disease. Bile Duct Cancer Overview[…] [froedtert.com]

Waardenburg Syndrome Type 4C

skin patches Patchy loss of skin color 0001053 Leukodystrophy 0002415 Muscular hypotonia Low or weak muscle tone 0001252 Nystagmus Involuntary, rapid, rhythmic eye movements [rarediseases.info.nih.gov]

Undescended testis [ more ] 0000028 Global developmental delay 0001263 Heterochromia iridis Different colored eyes 0001100 Hypogonadism Decreased activity of gonads 0000135 Hypopigmented [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 2A

Also characteristic are the white forelock, poliosis, and hypopigmented skin patches. [disorders.eyes.arizona.edu]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome? [dermnetnz.org]

skin patches Patchy loss of skin color 0001053 Sensorineural hearing impairment 0000407 White forelock White part of hair above forehead 0002211 5%-29% of people have these [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 2B

[…] graying Premature graying Premature greying Premature hair graying [ more ] 0002216 30%-79% of people have these symptoms Heterochromia iridis Different colored eyes 0001100 Hypopigmented [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 2D

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome ? [dermnetnz.org]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome? [dermnetnz.org]

Waardenburg Syndrome Type 2C

Also characteristic are the white forelock, poliosis, and hypopigmented skin patches. [disorders.eyes.arizona.edu]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome? [dermnetnz.org]