Hypopigmented Skin: Causes & Reasons

Possible Causes for Hypopigmented Skin

Clinical findings Range from benign hypopigmented skin macules, to profound mental retardation with intractable seizures and premature death due to disease-associated causes [medical-dictionary.thefreedictionary.com]

He additionally had two hypopigmented lesions on the skin. He underwent resection of the left parietal lobe 32months after seizure onset. [ncbi.nlm.nih.gov]

TSC is a generic disorder characterized by abnormal skin pigmentations (hypopigmented macules, shagreen patches) and tumor formation in multiple organ systems (brain, heart [med.uth.edu]

Vitiligo

Vitiligo-like lesions, defined as hypopigmented skin lesions, have already been associated with the use of ICIs in particular in patients with malignant melanoma, probably [ncbi.nlm.nih.gov]

since reduced tanning of normal skin will decrease the contrast with hypopigmented skin.[4] Most patients with nevus depigmentosus do not pursue treatment for their lesion [en.wikipedia.org]

Examination with Wood's lamp is often helpful to see the hypopigmented skin lesions of this condition. Mild to moderate growth restriction is common. [patient.info]

Phenylketonuria

Four additional cases of PKU diagnosed were siblings of screening detected cases who all presented with mental retardation, microcephaly, hypopigmented hair and skin and seizures [ncbi.nlm.nih.gov]

Toxic Liver Disease

Advanced Search Help Advanced search lets you search selected properties of the classification. You could search all properties or a selected subset only First, you need to provide keywords in the Search Text field then check the properties that you'd like to include in the search. The system will search for the[…] [icd.who.int]

Hyperphenylalaninemia

Homepage Rare diseases Search Search for a rare disease Hyperphenylalaninemia due to tetrahydrobiopterin deficiency Disease definition Hyperphenylalaninemia (HPA) due to tetrahydrobiopterin (BH4) deficiency, also known as malignant HPA is an amino acid disorder with neonatal onset that is clinically characterized by[…] [orpha.net]

Prader-Willi Syndrome

Prader-Willi Syndrome NORD is very grateful to Merlin G. Butler, MD, PhD, Director, Division of Research and Genetics, Director, KUMC Genetics Clinic and Professor of Psychiatry & Behavioral Sciences and Pediatrics, University of Kansas Medical Center, for assistance in the preparation of this report. Synonyms of[…] [rarediseases.org]

Extensive Burns

Abstract To investigate circulating cytokine responsiveness in major burns in association with the systemic stress response system, we tested hypothalamic-pituitary-adrenal (HPA) axis markers in extensive burn cases treated in the Department of Plastic and Reconstructive Surgery at Nagasaki University. The HPA[…] [ncbi.nlm.nih.gov]

Cartilage Hair Hypoplasia

Record: found Abstract: found Article: found Is Open Access Hipoplasia cartílago-cabello. Reporte de un caso Translated title: Cartilage-hair hypoplasia. A case report Publication date (Print and electronic): September 2019 Read this article at There is no author summary for this article yet. Authors can add[…] [scienceopen.com]

Pityriasis Alba

When to Contact a Medical Professional Call your provider if your child has patches of hypopigmented skin. References Dinulos JGH. [mountsinai.org]

Pityriasis alba is a common skin disorder of patches of light-colored (hypopigmented) areas. The cause is unknown but may be linked to atopic dermatitis (eczema). [nlm.nih.gov]

It is more noticeable in children with dark skin. Definition Pityriasis alba is a common skin disorder of patches of light-colored (hypopigmented) areas. [account.allinahealth.org]

Dyschromatosis Universalis Hereditaria Type 1

skin patches and hyperpigmented/hypopigmented macules. [selfdecode.com]

Additionally, many immature melanosomes were observed in hypopigmented skin region. [journals.plos.org]

Abstract Dyschromatosis is a pigmentary genodermatosis which presents with hyper and hypopigmented skin lesions giving a mottled appearance. [e-ijd.org]

Incontinentia Pigmenti Achromians

Definition Hypomelanosis of Ito (HMI) is a very rare birth defect that causes unusual patches of light-colored (hypopigmented) skin and may be associated with eye, nervous [ufhealth.org]

skin and may be associated with eye, nervous system, and skeletal problems. [mountsinai.org]

[…] derived from a hypopigmented skin area of M.B., with a slowly decreasing tetraploidy rate in the course of passaging: #2 23%, #5 11%, #11 and #14 6% and #18 and #21 2%. [ncbi.nlm.nih.gov]

Dyschromatosis Symmetrica Hereditaria

(d) In the hypopigmented skin, http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png The Journal of Dermatology Wiley http://www.deepdyve.com/lp/wiley/ultrastructural-study-of-dyschromatosis-symmetrica-hereditaria-with-mmu1SSryNV [deepdyve.com]

Hyperpigmented hair was also found in normal and hypopigmented skin. The colors of the hair and the skin did not correlate. [ncbi.nlm.nih.gov]

skin patches and hyperpigmented/hypopigmented macules. [selfdecode.com]

Piebaldism

Patches of hypopigmented skin and hair in these disorders represent regions lacking in melanocytes, the result of defective melanoblast differentiation, migration, proliferation [ncbi.nlm.nih.gov]

[…] of hypopigmented and depigmented skin areas (leukoderma) on various parts of the body, preferentially on the forehead, chest, abdomen, upper arms, and lower extremities, [orpha.net]

Preferred Name Piebaldism Synonyms Piebaldism (disorder) Definitions Piebaldism is a rare congenital pigmentation skin disorder with characteristic of the presence of hypopigmented [bioportal.bioontology.org]

Klein-Waardenburg Syndrome

Hypopigmented skin patches are sometimes present but not all patients have them. Genetics The uniqueness of Waardenburg syndrome types 1 and 3 remains to be established. [disorders.eyes.arizona.edu]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome ? [dermnetnz.org]

Individuals with type 1 often have a white forelock (29%), premature graying (44%), and hypopigmented skin patches (55%). A few patients have cleft palate and/or lip. [disorders.eyes.arizona.edu]

Tinea Versicolor

Hyperpigmented skin had thicker stratum corneum than hypopigmented but both were thicker than the uninvolved skin. [ncbi.nlm.nih.gov]

The hyperpigmented skin showed the stratum corneum to be leaner than in the hypopigmented skin, but in both the stratum corneum was thinner than in non-affected skin. [scielo.br]

Abstract A comparative histopathologic study is made between the hypopigmented and hyperpigmented skin lesions of pityriasis versicolor and normal skin areas utilizing histochemical [ncbi.nlm.nih.gov]

Dyschromatosis Universalis Hereditaria

Additionally, many immature melanosomes were observed in hypopigmented skin region. [journals.plos.org]

[…] macules, atrophic skin, palmoplantar pitting Dyschromatosis symmetrica hereditaria – reticular hypo- and hyperpigmented macules limited to face and acral areas Xeroderma [visualdx.com]

Abstract Dyschromatosis is a pigmentary genodermatosis which presents with hyper and hypopigmented skin lesions giving a mottled appearance. [e-ijd.org]

Ermine Phenotype

Affiliated tissues include skin, and related phenotypes are sensorineural hearing impairment and hypopigmented skin patches [malacards.org]

Showing of 22 | 80%-99% of people have these symptoms Hypopigmentation of hair Loss of hair color 0005599 Hypopigmented skin patches Patchy loss of skin color 0001053 Sensorineural [rarediseases.info.nih.gov]

Borderline Leprosy

skin patches. [casereports.bmj.com]

There are various forms whose descriptions differ among two different classification systems, but the three cardinal clinical manifestations of leprosy are hypopigmented skin [amboss.com]

skin macules and anaesthetic patches, where skin sensations are lost because of damaged peripheral nerves that have been attacked by the host's immune cells. [wikidoc.org]

Schimmelpenning-Feuerstein-Mims Syndrome

Case Reports doi: 10.1159/000070948. Affiliations PMID: 12835555 DOI: 10.1159/000070948 Case Reports Schimmelpenning-Feuerstein-Mims syndrome with hypophosphatemic rickets M Zutt et al. Dermatology. 2003. Abstract The Schimmelpenning-Feuerstein-Mims syndrome (SFM syndrome) is a rare and variable multisystem defect[…] [pubmed.ncbi.nlm.nih.gov]

Mirizzi Syndrome

Record: found Abstract: found Article: found Is Open Access Le syndrome de Mirizzi: une cause rare de l’obstruction des voies biliaires: à propos d’un cas et revue de littérature Translated title: Mirizzi’s syndrome: a rare cause of biliary tract obstruction: about a case and review of the literature Publication[…] [scienceopen.com]

Cholangiocarcinoma

Käännökset Yksikielisiä esimerkkejä Couch initially thought about selling the studio in 2014 after being diagnosed with a rare bile duct cancer with a less than 5 percent five-year survival rate. In addition to your medical history and physical examination, some of these tests may be performed to diagnose bile duct[…] [fi.bab.la]

Waardenburg Syndrome Type 4C

skin patches Premature graying of hair White eyebrow White eyelashes White forelock Abnormality of the nervous system Aganglionic megacolon Anosmia Ear malformation Sensorineural [ncbi.nlm.nih.gov]

Hypopigmented skin patches MedGen UID: 373164 •Concept ID: C1836735 • Finding White eyelashes MedGen UID: 332275 •Concept ID: C1836736 • Finding White color (lack of pigmentation [ncbi.nlm.nih.gov]

skin patches Leukodystrophy Muscular hypotonia Nystagmus Polyneuropathy Sensorineural hearing impairment Spastic paraparesis (Source: Wardenburg Syndrome Type 4; Genetic [dovemed.com]

Griscelli Syndrome

People with Griscelli syndrome type 2 have immune system abnormalities in addition to having hypopigmented skin and hair. [encyclopedia.pub]

Description Griscelli syndrome is an inherited condition characterized by unusually light (hypopigmented) skin and light silvery-gray hair starting in infancy. [medlineplus.gov]

Griscelli syndrome is an inherited condition characterized by unusually light (hypopigmented) skin and light silvery-gray hair starting in infancy. [ghr.nlm.nih.gov]

Familial Transverse Nasal Hyperpigmentation

OMIM:145250 Spastic Paraplegia-Facial-Cutaneous Lesions Syndrome Hyperpigmentation of the skin, Hypopigmented skin patches ORPHA:2819 Hyperbilirubinemia, Rotor Type Abnormality [mousephenotype.org]

The most typical presentation is that of a transverse hyperpigmented or hypopigmented skin line, but sometimes it is accompanied by other cutaneous lesions. [jaci-inpractice.org]

This line can be erythematous, hypopigmented, or hyperpigmented, and in some cases associated with comedones or milia cysts. [actasdermo.org]

Westerhof-Beemer-Cormane Syndrome

Hyperpigmented, normal and hypopigmented skin of one person had histological features of black oriental and white skin. [jamanetwork.com]

[…] of light-colored or dark-colored skin lesions along-with short stature and mental health issues A treatment of Hereditary Congenital Hypopigmented and Hyperpigmented Macules [dovemed.com]

DISCUSSION FPHH is a rare congenital genodermatosis that is characterized by hyper- and hypopigmented patches in the skin. [scielo.br]

Pityriasis Rotunda

Lesions are usually darker than surrounding skin (hyperpigmented) in patients with dark skin and lighter (hypopigmented) in patients with light skin. [dermnetnz.org]

These individuals do not have any associated malignancy or systemic diseases, but have multiple lesions that are lighter (hypopigmented) than the surrounding skin. [rarediseases.info.nih.gov]

Type 2 affects people with lighter skin who are younger than 40 years. [rarediseases.info.nih.gov]

Waardenburg Syndrome Type 2E

skin patches Premature graying of hair White eyebrow White eyelashes White forelock Abnormality of the musculoskeletal system Axial hypotonia Hypertonia Pectus excavatum [ncbi.nlm.nih.gov]

skin patches ; Hypoplasia of the iris ; Hypoplasia of the semicircular canal ; Intellectual disability ; Muscular hypotonia of the trunk ; Nystagmus ; Ocular albinism ; Pectus [mousephenotype.org]

skin patches Premature graying of hair White eyebrow White eyelashes White forelock Abnormality of the musculature ... ... [familydiagnosis.com]

Familial Progressive Hyperpigmentation with or without Hypopigmentation

skin patches Progressive hyperpigmentation Vitiligo Types of Familial progressive hyperpigmentation with or without hypopigmentation Some types of this condition may include [familydiagnosis.com]

DUH is characterized by sharply demarcated brown macules of various sizes on diffusely hypopigmented skin, typically involving the head, anterior chest, abdomen and extremities [ijdvl.com]

BACKGROUND: Familial progressive hyper- and hypopigmentation (FPHH) is a rare genodermatosis that is characterized by diffuse hyper- and hypopigmented spots on the skin and [ncbi.nlm.nih.gov]

Nevus Anemicus

The intervening skin often appears erythematous and will blanch with pressure, making the hypopigmented macules disappear. [dermatologyadvisor.com]

Nevus anemicus is an anomaly of the skin characterized as a patch of pale skin compared to the surrounding skin. [patientslikeme.com]

A skin biopsy may be performed, showing normal skin and thus ruling out other hypopigmented or depigmented lesions such as vitiligo. [ncbi.nlm.nih.gov]

Waardenburg Syndrome Type 2D

skin patches　(皮膚低色素斑)　[HP:0001053]　[18014] 　Sensorineural hearing impairment　(感音難聴)　[HP:0000407]　[0910] 　White forelock　(白色の前髪)　[HP:0002211]　[17101] 　　<5%-29%> 　Abnormality [syndromefinder.ncchd.go.jp]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome ? [dermnetnz.org]

Hypopigmented patches of skin are more susceptible to sun damage, so sun protection is important. What is the outcome for Waardenburg syndrome? [dermnetnz.org]