Hypoplastic Nails: Causes & Reasons

Possible Causes for Hypoplastic Nails

The most common clinical findings are a hypoplastic patella, elbow dysplasia, iliac horns, and hypoplastic nails. [insights.ovid.com]

[…] doi: 10.2106/JBJS.JOPA.17.00004 Review Article Abstract Author Information Authors Article Metrics Metrics Nail-patella syndrome (NPS) is an autosomal-dominant dysmorphic [journals.lww.com]

Clinically, the key feature is absent/hypoplastic nails from birth. Individuals may have flexion contractures and recurrent knee dislocations. [radiopaedia.org]

Ellis-Van Creveld Syndrome

nails. [ncbi.nlm.nih.gov]

Ellis-van Creveld (EVC) syndrome is a rare autosomal recessive disorder characterized by hypoplastic nails, polydactyly, and achondroplasia. [ncbi.nlm.nih.gov]

Clinical features were: a marked acromesomelic short stature (135 cm height), narrow thorax, genu valgum, club feet, brachydactyly, malposed toes, hypoplastic nails and teeth [ncbi.nlm.nih.gov]

Turner Syndrome

In infants, the combination of dysplastic or hypoplastic nails and lymphedema gives a characteristic sausage-like appearance to the fingers and toes. [emedicine.medscape.com]

Other characteristic physical findings These may include the following: Dental: A high arched palate, sometimes with dental crowding or malocclusion Nails: Hypoplastic or [emedicine.medscape.com]

[…] hyperconvex nails Nevi: Excessive numbers of nevi, when compared to other family members Webbed neck: A broad neck and a low or indistinct hairline Cubitus valgus (increased [emedicine.medscape.com]

Adams-Oliver Syndrome Type 2

nails. [epos.myesr.org]

In addition to scalp defect, the patient also had transverse terminal limb anomalies such as brachydactyly, cutaneous syndactyly, and hypoplastic nails [Figure 1]a,[Figure [advbiores.net]

A male infant with scalp and skin cutis aplasia, generalized cutis aplasia, dilated veins over scalp and trunk, hypoplastic toes and nails of feet, glaucoma, poor feeding [mdpi.com]

Schöpf-Schulz-Passarge Syndrome

It is characterized by palmoplantar keratoderma, eyelid apocrine hydrocystomas, hypodontia, hypotrichosis and hypoplastic nails. [karger.com]

Adams-Oliver Syndrome

The full spectrum of observed defects ranges from hypoplastic nails, cutaneous syndactyly, bony syndactyly, transverse reduction defects, zygodactyly, ectrodactyly, polydactyly [escholarship.org]

A male infant with scalp and skin cutis aplasia, generalized cutis aplasia, dilated veins over scalp and trunk, hypoplastic toes and nails of feet, glaucoma, poor feeding [pagepress.org]

Simpson-Golabi-Behmel Syndrome Type 2

Small nail Hypoplastic nails A nail that is diminished in length and width, i.e., underdeveloped nail. [rarediseases.oscar.ncsu.edu]

Epidermolysis Bullosa

The nails are deformed or absent. The teeth are hypoplastic, and extensive caries develop early in life. Death may occur in early life. Case Reports Case I: M. [pubs.rsna.org]

Hypoplastic enamel formation causes tooth decay. Nail dystrophy and alopecia are also common. They have a normal life expectancy and ability to reproduce. [patient.info]

Trachonychia

[…] or absent • Renal involvement • Infection • Chronic paronychia caused by • Dorsal pterygium – Proximal nail fold scarring – Ventral nail plate and hyponychium fused – Congenital [brainscape.com]

Steatocystoma multiplex • Natal teeth • No leukokeratosis • I, II, III and laryngeal disease, MR and amyloid Acute paronychia cause #1 – Proximal white subungual • Patellae hypoplastic [brainscape.com]

Onycholysis

[…] condition that includes hypoplastic, easily dislocated patellas, renal and skeletal abnormalities, and glaucoma. [aafp.org]

Koilonychia also may result from trauma, constant occupational exposure of the hands to petroleum-based solvents, or nail-patella syndrome. 11 The latter is an autosomal-dominant [aafp.org]

Hidrotic Ectodermal Dysplasia

[…] sebaceous glands hypoplastic-absent eccrine sweat glands spoon-shaped nails hypotrichosis fine, brittle hair scanty hair absent or scanty eyelashes and eyebrows blonde, fine [humpath.com]

Nails In this disorder, the nails are malformed, hypoplastic, thick, discolored (milky white), and unattached to the nail bed. [symptoma.com]

Top matches: Low match CLOUSTON SYNDROME The main features of Clouston syndrome are dystrophy of the nails that tend to be hypoplastic and deformed with increased susceptibility [mendelian.co]

Rapp-Hodgkin Syndrome

and conical teeth and hypodontia, and hypospadias and hypoplastic uvula in the boy. [unboundmedicine.com]

Oral findings may include hypodontia, hypoplastic enamel, cleft lip/palate, and a pronounced midfacial hypoplasia. [ncbi.nlm.nih.gov]

12-year-old brother had hypohidrotic ectodermal dysplasia, cleft lip and palate, midfacial hypoplasia with narrow nose from the nasal bridge to the tip, narrow dysplastic nails [unboundmedicine.com]

Distal Symphalangism

[…] hypoplasia/flat/short midface Thin/hyperconvex/hypoplastic nails Paresis of ocular muscles/squint Decreased hair pigmentation - patchy Short foot (including brachydactyly [head-face-med.biomedcentral.com]

The index finger is affected most typically, but reports of thumb and great toe involvement, with or without nail hypoplasia, have appeared in the literature (Matthews et [rrnursingschool.biz]

[…] carpals Hypertelorism Dental caries Other dental abnormality Absent/decreased eyebrows/lateral thinning Abnormal tooth position/malocclusion/open bite Thin/hyperconvex/hypoplastic [head-face-med.biomedcentral.com]

Iron Deficiency Anemia

Update of the US Preventive Services Task Force (USPSTF) 2006 recommendation on screening for iron deficiency anemia. The USPSTF reviewed the evidence on the association between change in iron status as a result of intervention and improvement in child health outcomes, as well as screening for and treatment of[…] [ncbi.nlm.nih.gov]

Psoriasis

Cochrane Database of Systematic Reviews Background Psoriasis is an immune‐mediated disease for which some people have a genetic predisposition. The condition manifests in inflammatory effects on either the skin or joints, or both, and it has a major impact on quality of life. Although there is currently no cure for[…] [doi.org]

Cronkhite-Canada Syndrome

BACKGROUND AND AIMS: Cronkhite-Canada syndrome (CCS) is a noninherited condition, associated with high morbidity, and characterized by gastrointestinal hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, and diarrhea. All features may respond to immunosuppressive therapy, but little is known about[…] [ncbi.nlm.nih.gov]

Plummer-Vinson Syndrome

Plummer-Vinson syndrome is a condition that affects mostly middle-aged caucasian women and is defined by the triad of iron deficiency anemia, upper esophageal webs and postcricoid dysphagia. Given that it can involve iron deficiency (sideropenia) without anemia, it has been also called sideropenic dysphagia. Dysphagia[…] [symptoma.com]

Peripheral Vascular Disease

The presence of peripheral vascular disease, in particular iliofemoral disease, is responsible in part for vascular complications from femoral artery cannulation. We investigated whether prescreening for vascular obstructions with magnetic resonance angiography (MRA) in high-risk patients with peripheral vascular[…] [ncbi.nlm.nih.gov]

Onychia

Definition of Onychia 1. n. A whitlow. Definition of Onychia 1. Noun. A whitlow. ¹ 2. Noun. An affection of a finger or toe, attended with ulceration at the base of the nail, and terminating in the destruction of the nail. ¹ ¹ Source: wiktionary.com Definition of Onychia 1. inflammation of the nail-bed [n -S] Medical[…] [lexic.us]

Wiedemann-Rautenstrauch Syndrome

There was generalized lack of subcutaneous fat, thin wrinkled skin, and hypoplastic nails. [omim.org]

Psoriatic Arthritis

Author information 1 From the University of Toronto and Women's College Hospital, Toronto; University of Ottawa, Ottawa Hospital Research Institute, Ottawa, Ontario; University of Alberta, Edmonton, Alberta, Canada; University of Florida College of Medicine, Jacksonville, Florida, USA; Copenhagen Center for Arthritis[…] [ncbi.nlm.nih.gov]

Williams-Beuren Syndrome

nails, short stature, microcephaly, hypotonia, developmental delay, hyperacusis, mental retardation, overfriendliness, hyperactivity, anxiety, and loquaciousness. [scielo.br]

nails showed a significant association on univariate analysis at a = 0.05, but the P values were closer to the a value than the value corrected for Bonferroni's error; these [scielo.br]

[…] coarctation, non-SVA congenital heart disease, umbilical/inguinal hernia, kidney anomalies, arterial hypertension, hypercalcemia, joint contractures, fifth finger clinodactyly, hypoplastic [scielo.br]

Hypoparathyroidism

Hypoparathyroidism presents the following signs and symptoms: Pain in the abdomen Cataract Muscle cramps and carpopedal spasms Weakening of tooth enamel Painful menstrual cycle Seizures Tingling sensation in the hands, fingers and feet Brittle nails Dry skin Depression Fatigue Loss of hair and hair thinning in[…] [symptoma.com]

Juvenile Myxedema

CLINICAL STUDIES ON A CASE OF AGAMMAGLOBULINEMIA AND JUVENILE MYXEDEMA Hiroshi SAITO, Fumio KOMATSU, Mieko MATSUDA, Toshihiro MIWA, Bunmei INATSUKI, Tsuneo ABE Author information JOURNALS FREE ACCESS 1974 Volume 63 Issue 7 Pages 643-650 DOI https://doi.org/10.2169/naika.63.643 Details Download PDF (1184K) Download[…] [jstage.jst.go.jp]

Myxedema

Ureteral myxedema is exceptionally rare. We describe computed tomography and magnetic resonance imaging findings in a case of ureteral myxedema. The demonstration of water-like hyperintensity around the ureteral lumen on heavily T2-weighted sequences should be considered a strongly suggestive sign for ureteral[…] [ncbi.nlm.nih.gov]

Curry-Hall Syndrome

[…] toenails Underdeveloped toenails 0001800 Mild short stature 0003502 Nail dystrophy Poor nail formation 0008404 Postaxial hand polydactyly Extra little finger Extra pinkie [rarediseases.info.nih.gov]

[…] toenails Oval face Enuresis nocturna Abnormality of the dentition Protruding ear Nail dystrophy Hypodontia Nail dysplasia Postaxial hand polydactyly Hypotelorism Abnormality [mendelian.co]

[…] teeth Early eruption of teeth 0006288 Conical tooth Cone shaped tooth Shark tooth [ more ] 0000698 Hypodontia Failure of development of between one and six teeth 0000668 Hypoplastic [rarediseases.info.nih.gov]

Secondary Syphilis

Dear Editor, Syphilis is an infection caused by Treponema pallidum. Without treatment, it goes through the following stages: primary, secondary, latent, and tertiary (1). The clinical picture of secondary syphilis is very variable (2,3). We present two rare cases of secondary syphilis, one with nodular lesions initially[…] [ncbi.nlm.nih.gov]

Fetal Hydantoin Syndrome

The nails generally reflect the size and shape of the underlying distal phalanx (e.g., hypoplastic nail, narrow hyperconvex nail, short broad nail). Figure 1.100. [rrnursingschool.biz]

Fetal Hydantoin syndrome mnemonic - PHENytoin Fetal hydantoin syndrome involves microcephaly, dysmorphic craniofacial features, hypoplastic nails, hypoplastic distal phalanges [medicowesome.com]

nails and distal phalanges ( birth defects ). [ipfs.io]

Congenital Onychodysplasia

The second presented with bilateral hypoplastic nail of the index finger and bilateral symphalangism of the fifth finger; aplastic distal phalanges of the second finger was [ncbi.nlm.nih.gov]

The second presented with bilateral hypoplastic nail of theindex finger and bilateral symphalangism of the fifth finger; aplastic distalphalanges of the second finger was [docslide.com.br]

Alteration in size of nail Hypoplastic nails (micronychia/anonychia) are seen in various ectodermal dysplasia [Table 3], epidermolysis bullosa [Figure 7] and nail-patella [ijdvl.com]

Congenital Ankyloblepharon

Curly hair, ankyloblepharon and nail dysplasia (CHAND) syndrome: An autosomal recessive disorder characterised by ankyloblepharon, ectodermal dysplasia, curly hair and hypoplastic [eyewiki.aao.org]

nails, accessory nipple, and partially descended testis has also been reported.[10] This report demonstrates the simplicity in treating the condition and the importance of [jcor.in]

nails, with absence of cleft lip or palate. [eyewiki.aao.org]