Hypoplastic Nails: Causes & Reasons

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Possible Causes for Hypoplastic Nails

Nail-Patella Syndrome

Associations renal dysfunction 5 Clinically, the key feature is absent or hypoplastic nails from birth. [radiopaedia.org]

The most common clinical findings are a hypoplastic patella, elbow dysplasia, iliac horns, and hypoplastic nails. [insights.ovid.com]

[…] doi: 10.2106/JBJS.JOPA.17.00004 Review Article Abstract Author Information Authors Article Metrics Metrics Nail-patella syndrome (NPS) is an autosomal-dominant dysmorphic [journals.lww.com]

Ellis-Van Creveld Syndrome

nails. [ncbi.nlm.nih.gov]

Ellis-van Creveld (EVC) syndrome is a rare autosomal recessive disorder characterized by hypoplastic nails, polydactyly, and achondroplasia. [ncbi.nlm.nih.gov]

Clinical features were: a marked acromesomelic short stature (135 cm height), narrow thorax, genu valgum, club feet, brachydactyly, malposed toes, hypoplastic nails and teeth [ncbi.nlm.nih.gov]

Turner Syndrome

In infants, the combination of dysplastic or hypoplastic nails and lymphedema gives a characteristic sausage-like appearance to the fingers and toes. [emedicine.medscape.com]

Other characteristic physical findings These may include the following: Dental: A high arched palate, sometimes with dental crowding or malocclusion Nails: Hypoplastic or [emedicine.medscape.com]

[…] hyperconvex nails Nevi: Excessive numbers of nevi, when compared to other family members Webbed neck: A broad neck and a low or indistinct hairline Cubitus valgus (increased [emedicine.medscape.com]

Simpson-Golabi-Behmel Syndrome Type 2

Small nail Hypoplastic nails A nail that is diminished in length and width, i.e., underdeveloped nail. [rarediseases.oscar.ncsu.edu]

Schöpf-Schulz-Passarge Syndrome

It is characterized by palmoplantar keratoderma, eyelid apocrine hydrocystomas, hypodontia, hypotrichosis and hypoplastic nails. [karger.com]

(onychodystrophy), such as nail fragility or hypoplastic nails. [dermnetnz.org]

[…] middle-age Thickening of the skin on the hands and the feet (palmoplantar keratoderma) Excessive sweating (hyperhidrosis) Sparse hair (hypotrichosis) Malformation of the nails [dermnetnz.org]

Adams-Oliver Syndrome Type 2

The most common limb anomalies are hypoplastic or absent distal phalanges, but defects range from hypoplastic nails to completely absent hands or lower legs [5]. [cureus.com]

Adams-Oliver Syndrome

The full spectrum of observed defects ranges from hypoplastic nails, cutaneous syndactyly, bony syndactyly, transverse reduction defects, zygodactyly, ectrodactyly, polydactyly [escholarship.org]

A male infant with scalp and skin cutis aplasia, generalized cutis aplasia, dilated veins over scalp and trunk, hypoplastic toes and nails of feet, glaucoma, poor feeding [pagepress.org]

Epidermolysis Bullosa

The nails are deformed or absent. The teeth are hypoplastic, and extensive caries develop early in life. Death may occur in early life. Case Reports Case I: M. [pubs.rsna.org]

Hypoplastic enamel formation causes tooth decay. Nail dystrophy and alopecia are also common. They have a normal life expectancy and ability to reproduce. [patient.info]

Trachonychia

[…] or absent • Renal involvement • Infection • Chronic paronychia caused by • Dorsal pterygium – Proximal nail fold scarring – Ventral nail plate and hyponychium fused – Congenital [brainscape.com]

Steatocystoma multiplex • Natal teeth • No leukokeratosis • I, II, III and laryngeal disease, MR and amyloid Acute paronychia cause #1 – Proximal white subungual • Patellae hypoplastic [brainscape.com]

Onycholysis

[…] condition that includes hypoplastic, easily dislocated patellas, renal and skeletal abnormalities, and glaucoma. [aafp.org]

Koilonychia also may result from trauma, constant occupational exposure of the hands to petroleum-based solvents, or nail-patella syndrome. 11 The latter is an autosomal-dominant [aafp.org]

Hidrotic Ectodermal Dysplasia

[…] sebaceous glands hypoplastic-absent eccrine sweat glands spoon-shaped nails hypotrichosis fine, brittle hair scanty hair absent or scanty eyelashes and eyebrows blonde, fine [humpath.com]

Nails In this disorder, the nails are malformed, hypoplastic, thick, discolored (milky white), and unattached to the nail bed. [symptoma.com]

Top matches: Low match CLOUSTON SYNDROME The main features of Clouston syndrome are dystrophy of the nails that tend to be hypoplastic and deformed with increased susceptibility [mendelian.co]

Rapp-Hodgkin Syndrome

and conical teeth and hypodontia, and hypospadias and hypoplastic uvula in the boy. [unboundmedicine.com]

Oral findings may include hypodontia, hypoplastic enamel, cleft lip/palate, and a pronounced midfacial hypoplasia. [jmg.bmj.com]

Rapp-Hodgkin syndrome (RHS) is a rare form of ectodermal dysplasia with variable involvement of the hair, eyes, sweat glands, nails, and teeth. [ncbi.nlm.nih.gov]

Distal Symphalangism

[…] hypoplasia/flat/short midface Thin/hyperconvex/hypoplastic nails Paresis of ocular muscles/squint Decreased hair pigmentation - patchy Short foot (including brachydactyly [head-face-med.biomedcentral.com]

The index finger is affected most typically, but reports of thumb and great toe involvement, with or without nail hypoplasia, have appeared in the literature (Matthews et [rrnursingschool.biz]

[…] carpals Hypertelorism Dental caries Other dental abnormality Absent/decreased eyebrows/lateral thinning Abnormal tooth position/malocclusion/open bite Thin/hyperconvex/hypoplastic [head-face-med.biomedcentral.com]

Iron Deficiency Anemia

Abstract Ankaferd Blood Stopper (ABS) comprises a mixture of plants and stops bleeding via forming a protein network by erythroid aggregation. Bleeding causes reduction of iron levels in body. It has been indicated that ABS contains significant amount of iron. Thus, we investigated the biological activity of[…] [ncbi.nlm.nih.gov]

Psoriasis

Overview Psoriasis is a skin disease that causes a rash with itchy, scaly patches, most commonly on the knees, elbows, trunk and scalp. Psoriasis is a common, long-term (chronic) disease with no cure. It can be painful, interfere with sleep and make it hard to concentrate. The condition tends to go through cycles,[…] [mayoclinic.org]

Cronkhite-Canada Syndrome

Cronkhite‑Canada syndrome (CCS) is a rare non‑inherited condition characterized by gastrointestinal (GI) hamartomatous polyposis, alopecia, onychodystrophy, hyperpigmentation, weight loss and diarrhea. The etiology is most likely autoimmune and diagnosis is based on patient history, physical examination, endoscopic[…] [spandidos-publications.com]

Plummer-Vinson Syndrome

Plummer-Vinson syndrome is a condition that affects mostly middle-aged caucasian women and is defined by the triad of iron deficiency anemia, upper esophageal webs and postcricoid dysphagia. Given that it can involve iron deficiency (sideropenia) without anemia, it has been also called sideropenic dysphagia. Dysphagia[…] [symptoma.com]

Peripheral Vascular Disease

Peripheral vascular disease, abbreviated as PVD, is a condition characterized by obstruction of large arteries, causing the blood supply to reduce significantly. Such a type of condition is also referred to as Peripheral arterial disease. Intermittent claudication, characterized by pain in leg, experienced while walking,[…] [symptoma.com]

Onychia

3 short excerpts of WikWik.org (WikWik is an online database of words defined in the English, French, Spanish, Italian, and other Wiktionnaries.) onychia n. A whitlow. onychia n. An affection of a finger or toe, attended with ulceration at the base of the nail, and terminating[…] onychia n. plural of onychium. 18 valid[…] [1word.ws]

Wiedemann-Rautenstrauch Syndrome

There was generalized lack of subcutaneous fat, thin wrinkled skin, and hypoplastic nails. [omim.org]

Psoriatic Arthritis

Abstract A middle-aged man presented for left foot diabetic ulcer care. Pedal radiographs were negative for signs of osteomyelitis. However, asymptomatic incidental osseous findings demonstrated significant plantar and posterior calcaneal spurring possibly consistent with diffuse idiopathic skeletal hyperostosis[…] [ncbi.nlm.nih.gov]

Williams-Beuren Syndrome

nails, short stature, microcephaly, hypotonia, developmental delay, hyperacusis, mental retardation, overfriendliness, hyperactivity, anxiety, and loquaciousness. [scielo.br]

nails showed a significant association on univariate analysis at a = 0.05, but the P values were closer to the a value than the value corrected for Bonferroni's error; these [scielo.br]

[…] coarctation, non-SVA congenital heart disease, umbilical/inguinal hernia, kidney anomalies, arterial hypertension, hypercalcemia, joint contractures, fifth finger clinodactyly, hypoplastic [scielo.br]

Hypoparathyroidism

Hypoparathyroidism NORD gratefully acknowledges Dolores Shoback, MD, Professor of Medicine, UCSF Endocrine Research Unit - 111N, SF - VA Medical Center, for assistance in the preparation of this report. Subdivisions of Hypoparathyroidism acquired hypoparathyroidism autoimmune hypoparathyroidism congenital[…] [rarediseases.org]

Juvenile Myxedema

PMID: 5527142 Case Reports Juvenile myxoedema A K Bhattacharya. Bull Calcutta Sch Trop Med. 1970 Oct. No abstract available Similar articles Effect of 3:5:3'-L-triiodothyronine in myxoedema. GROSS J, PITT-RIVERS R, TROTTER WR. GROSS J, et al. Lancet. 1952 May 24;1(6717):1044-5. doi: 10.1016/s0140-6736(52)90695-8.[…] [pubmed.ncbi.nlm.nih.gov]

Myxedema

Myxedema coma occurs as a result of long-standing, undiagnosed, or undertreated hypothyroidism and is usually precipitated by a systemic illness. Myxedema coma can result from any of the causes of hypothyroidism, most commonly chronic autoimmune thyroiditis. It can also occur in patients who had thyroidectomy or[…] [emedicine.com]

Curry-Hall Syndrome

[…] toenails Underdeveloped toenails 0001800 Mild short stature 0003502 Nail dystrophy Poor nail formation 0008404 Postaxial hand polydactyly Extra little finger Extra pinkie [rarediseases.info.nih.gov]

[…] toenails Oval face Enuresis nocturna Abnormality of the dentition Protruding ear Nail dystrophy Hypodontia Nail dysplasia Postaxial hand polydactyly Hypotelorism Abnormality [mendelian.co]

[…] teeth Early eruption of teeth 0006288 Conical tooth Cone shaped tooth Shark tooth [ more ] 0000698 Hypodontia Failure of development of between one and six teeth 0000668 Hypoplastic [rarediseases.info.nih.gov]

Secondary Syphilis

Anetoderma is a rare benign condition of diverse etiology whose characteristic is the diminution or absence of the dermal elastic fibers. Classified as primary and secondary, the latter associated with tumors, inflammatory, and infectious diseases. Although the etiology of the lesions is well described in literature,[…] [ncbi.nlm.nih.gov]

Fetal Hydantoin Syndrome

The nails generally reflect the size and shape of the underlying distal phalanx (e.g., hypoplastic nail, narrow hyperconvex nail, short broad nail). Figure 1.100. [rrnursingschool.biz]

Fetal Hydantoin syndrome mnemonic - PHENytoin Fetal hydantoin syndrome involves microcephaly, dysmorphic craniofacial features, hypoplastic nails, hypoplastic distal phalanges [medicowesome.com]

nails and distal phalanges ( birth defects ). [ipfs.io]

Congenital Onychodysplasia

The second presented with bilateral hypoplastic nail of the index finger and bilateral symphalangism of the fifth finger; aplastic distal phalanges of the second finger was [ncbi.nlm.nih.gov]

The second presented with bilateral hypoplastic nail of theindex finger and bilateral symphalangism of the fifth finger; aplastic distalphalanges of the second finger was [docslide.com.br]

Alteration in size of nail Hypoplastic nails (micronychia/anonychia) are seen in various ectodermal dysplasia [Table 3], epidermolysis bullosa [Figure 7] and nail-patella [ijdvl.com]

Congenital Ankyloblepharon

Curly hair, ankyloblepharon and nail dysplasia (CHAND) syndrome: An autosomal recessive disorder characterised by ankyloblepharon, ectodermal dysplasia, curly hair and hypoplastic [eyewiki.aao.org]

nails, accessory nipple, and partially descended testis has also been reported.4 In both the cases we could not find any causative factor for the defect as the perinatal [ncbi.nlm.nih.gov]

nails, with absence of cleft lip or palate. [eyewiki.aao.org]