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15 Possible Causes for Hypoplastic Phalanges, Stiffness of the Lower Limbs

  • Spinal Stenosis

    […] due to short metacarpals and hypoplastic terminal phalanges, thoracolumbar kyphoscoliosis, narrow transverse measurements of most vertebrae with prominent coccyx, spinal[ncbi.nlm.nih.gov] Recognisable skeletal abnormalities include hypoplastic facial bones, hypoplastic clavicles, narrow and anteriorly sloping shoulders, bowing of both forearm bones, brachydactyly[ncbi.nlm.nih.gov]

  • Spastic Paraplegia

    […] fifth middle phalanges [ Manzini et al 2010 ] Mild kyphoscoliosis has been reported but radiographic correlation was not available [ Proukakis et al 2004 ] Life expectancy[ncbi.nlm.nih.gov] […] and contraction (spasticity) in the lower limbs, as a result of damage to or dysfunction of the nerves.[dbpedia.org] […] and contraction (spasticity) in the lower limbs.[zfin.org]

  • Autosomal Recessive Spastic Paraplegia Type 20

    Nonspecific skeletal malformations were observed in the hands such as clinodactyly, camptodactyly, and hypoplastic 5th middle phalanges.[cags.org.ae] These disorders are characterized by progressive muscle stiffness (spasticity) and the development of paralysis of the lower limbs (paraplegia).[ghr.nlm.nih.gov] […] fifth middle phalanges [ Manzini et al 2010 ] Mild kyphoscoliosis has been reported but radiographic correlation was not available [ Proukakis et al 2004 ] Life expectancy[ncbi.nlm.nih.gov]

  • Craniosynostosis-Dandy-Walker Malformation-Hydrocephalus Syndrome

    (A) The newborn hand showing camptodactyly, hypoplastic terminal phalanges and absent nail on the fifth digit. (B) Hand X-rays.[dev.docslide.net] People with Dandy–Walker malformation may experience muscle stiffness and partial paralysis of the lower limbs (spastic paraplegia), and they may also have seizures.[en.wikipedia.org] […] terminal phalanges of fingers.[jcrpe.org]

  • Oculodentodigital Dysplasia

    Digital abnormalities include syndactyly of finger 4/5, and hypoplastic phalanges (Frasson et al. 2004; Musa et al. 2008; Jamsheer et al. 2014).[preventiongenetics.com] Paraparesis (partial paralysis of the lower extremities) Quadriparesis (Weakness of all four limbs, both arms and both legs) Seizures Spasticity (unusual “tightness”, stiffness[nfed.org] The middle phalanges of the digits are usually hypoplastic or may be absent. Syndactyly of fingers and toes is often a feature and camptodactyly is common.[disorders.eyes.arizona.edu]

  • Non-Syndromic Aplasia Cutis Congenita

    , metacarpals and phalanges.[nectarmutation.org] The most common limb malformation is hypoplastic or absent distal phalanges, but the severity of limb anomalies ranges from minor defects such as an absent nail or broad fingertip[emedicine.medscape.com] A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.[nectarmutation.org]

  • Weismann Netter Syndrome

    There is tapering of the distal phalanges with absence of the ungual tufts and segmentation anomalies of the vertebrae.[hormones.gr] […] of interphalangeal joints Lower limb Brachydactyly Soft tissue syndactyly of toes Broad deformed great toe Trapezoidalrst phalanx of great toe Broad lst metatarsal Accessory[zdoc.site] Radiographic examination shows an increased density of bone of the entire skeleton, osteosclerosis, delayed closure of cranial sutures, wormian bones, open fontanels and hypoplastic[hormones.gr]

  • Oculorenocerebellar Syndrome

    Onychonychia hypoplastic distal phalanges[?] Onychotrichodysplasia and neutropenia[?] Ophthalmophobia[?] Opitz Mollica Sorge syndrome[?][encyclopedia.kids.net.au] limbs Red hair Morphological abnormality of the pyramidal tract Areflexia of lower limbs Woolly hair Bulbar signs Motor axonal neuropathy Facial diplegia Joint stiffness[mendelian.co] […] distal phalanges Onychophosis Onychotrichodysplasia and neutropenia Op [ edit ] Opi-Ops [ edit ] Opioid dependence Opioid-induced hyperalgesia Ophthalmic icthyosis Ophthalmo[en.wikipedia.org]

  • Lethal Multiple Pterygium Syndrome

    The phalanges were hypoplastic. Chromosomes (cultured amniocytes) were normal (46,XY). Lethal Multiple Pterygium Syndrome 915 Fig. 2.[documents.tips] In the lower limbs, the hips may be dislocated, the knees are extended, and the feet have severe equinovarus contractures.[clinicalgate.com] Radiographic examination (Fig. 3) demonstrated broad clavicles and ribs, abnormal jaw angle, hypoplastic radii and phalanges, apparent cutaneous syndactyly of the fingers,[documents.tips]

  • Aplasia Cutis - Myopia Syndrome

    Larger lesions, possible extension to dura mater Group1: AD or sporadic: scalp ACC without multiple anomalies Group2: scalp (midline) with limb abnormalities eg hypoplastic[brainscape.com] A form of spastic paraplegia, a neurodegenerative disorder characterized by a slow, gradual, progressive weakness and spasticity of the lower limbs.[nectarmutation.org] […] or absent distal phalanges • cutis marmorata telangiectatica congenita, hemangiomas, cranial arteriovenous malformation, skin tags, supernumerary nipples, and woolly hair[scielo.br]

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