Possible Causes for hyporeflexia Acute Alcohol Intoxication T-wave oversensing can be a serious problem that often results in inappropriate device therapy. We report here a patient with binge alcohol use who received multiple, inappropriate ICD shocks due to T-wave oversensing from repolarization changes induced by acute alcohol intoxication and no other relevant metabolic[…] [ncbi.nlm.nih.gov] Hyponatremia Apart from reduced muscle power (4/5) and hyporeflexia, the neurological examination was normal. [ncbi.nlm.nih.gov] Peripheral Neuropathy BACKGROUND: Even though chemotherapeutic regimens show considerable importance, it may cause progressive, continuing and sometimes irreversible peripheral neuropathy. Chemotherapy induced peripheral neuropathy (CIPN) is comprised of sensory abnormalities that are most distressing issues. The mechanism associated[…] [ncbi.nlm.nih.gov] Head Trauma INTRODUCTION: Head injuries represent a concern in skiing and snowboarding, with traumatic brain injuries being the most common cause of death. AIM: To describe the mechanisms of head and face injuries among World Cup alpine and freestyle skiers and snowboarders. METHODS: We performed a qualitative analysis of[…] [ncbi.nlm.nih.gov] Hyperkalemia Review CMAJ October 19, 2010 182 (15) 1631-1635; DOI: The case A 72-year-old man presents to his family physician for follow-up of hypertension, reporting fatigue and generalized weakness. His medical history also includes peptic ulcer disease, type 2 diabetes mellitus and chronic kidney disease. The estimated[…] [doi.org] Chronic Kidney Insufficiency Abstract Anemia is a major problem in patients with chronic kidney insufficiency. The development of recombinant human erythropoietin has enabled physicians to correct this anemia. Although anemia has not been considered to be a common or important contributor to congestive heart failure, anemia of any cause can[…] [ncbi.nlm.nih.gov] Stroke The therapeutic window for intervention in acute cerebral ischemia is brief. Prehospital identification of acute stroke patients and paramedic administration of neuroprotective agents may soon become critical components of successful acute stroke treatment. This preliminary study sought to demonstrate that a new[…] [ncbi.nlm.nih.gov] Benzodiazepine Overdose Generally, patients with benzodiazepine-induced coma have hyporeflexia and midposition or small pupils. Hypothermia may occur. [accessmedicine.mhmedical.com] Clinical features : CNS depressio n : lethargy, somnolence, hyporeflexia Respiratory depression Mild hypotension Ataxia Slurred speech Carbamazepine and oxcarbazepine: possibly [amboss.com] Pernicious Anemia In early stages, decreased position and vibratory sensation in the extremities is accompanied by mild to moderate weakness and hyporeflexia. [msdmanuals.com] Overdose J Anal Toxicol. 2018 May 1;42(4):255-264. doi: 10.1093/jat/bkx111. Author information 1 Service de Toxicologie, Hôpital Lariboisière, AP-HP, 2 Rue Ambroise Paré, Paris 75010, France. 2 Service Mobile d'Urgence et de Réanimation (SMUR), Hôpital Robert Debré, AP-HP, 48 Boulevard Sérurier, Paris 75019, France. 3 Service de[…] [ncbi.nlm.nih.gov] X-linked Distal Spinal Muscular Atrophy Type 3 They vary by the specific type and may include hypotonia; hyporeflexia; difficulty sucking, swallowing, and breathing; unmet developmental milestones; and, in more severe [merckmanuals.com] Patients typically present during infancy or early childhood with progressive weakness, hypotonia, muscle atrophy, hyporeflexia /areflexia, and varying degrees of bulbar weakness [amboss.com] Skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory failure, symmetric muscle atrophy and paralysis in patients with SMA. [ijp.mums.ac.ir] Guillain-Barré Syndrome Guillain-Barré syndrome (GBS) is characterized by rapidly evolving ascending weakness, mild sensory loss, and hyporeflexia or areflexia. [ncbi.nlm.nih.gov] Physical examination confirmed lower left facial palsy and paresthesia of his extremities with hyporeflexia of his lower limbs and sensory loss of all four extremities. [ncbi.nlm.nih.gov] Abstract Guillain-Barré syndrome (GBS), an immune-mediated demyelinating peripheral neuropathy, is characterized by acute weakness of the extremities and areflexia or hyporeflexia [ncbi.nlm.nih.gov] Muscular Dystrophy Becker muscular dystrophy is an inherited disorder that involves slowly worsening muscle weakness of the legs and pelvis. Becker muscular dystrophy is very similar to Duchenne muscular dystrophy. The main difference is that it gets worse at a much slower rate and it is less common. The disorder is passed down[…] [medlineplus.gov] Spinal and Bulbar Muscular Atrophy The patient clinical picture included gait impairment, global hyporeflexia, proximal muscle atrophy of upper limbs, deviation of the uvula to right during phonation and tongue [ncbi.nlm.nih.gov] […] bulbar muscles (those of the face and throat).The condition mainly affects males, with onset between the ages of 30 and 60. 0001288 Gynecomastia Enlarged male breast 0000771 Hyporeflexia [rarediseases.info.nih.gov] Distal Spinal Muscular Atrophy Type 1 The lower motor neuron involvement in disease can cause LMN manifestations such as fasciculation, atrophy, weakness, and hyporeflexia, Upper motor neurone involvement will [explainmedicine.com] Patients typically present during infancy or early childhood with progressive weakness, hypotonia, muscle atrophy, hyporeflexia /areflexia, and varying degrees of bulbar weakness [amboss.com] Skeletal and intercostal muscles denervation lead to weakness, hypotony, hyporeflexia, respiratory failure, symmetric muscle atrophy and paralysis in patients with SMA. [ijp.mums.ac.ir] Spinal Trauma Current Evaluation and Management Publication Date: Edition: Pages: Illustrations: Format: ISBN: January 1993 1 237 0 Hardback 9781879284197 Spinal Trauma: Current Evaluation and Management contains information and opinions by neurosurgical experts regarding still–evolving spinal trauma management techniques,[…] [thieme.com] Duchenne Muscular Dystrophy Duchenne muscular dystrophy (DMD) is the most common neuromuscular disease affecting boys. Advances in their care can delay the progression of DMD-related disability and prolong survival. The administration of glucocorticoids is among these advances. Glucocorticoid therapy, however, is associated with a myriad of[…] [ncbi.nlm.nih.gov] Subdural Hematoma BACKGROUND: Delayed acute subdural hematoma (DASH) is a subdural hematoma which is detected later. An initial computed tomography (CT) does not reveal any intracranial hemorrhage at all. Few patients of DASH after mild traumatic brain injury associated with percutaneous coronary intervention (PCI) have been[…] [ncbi.nlm.nih.gov] Rhabdomyolysis On admission, the patient was afebrile, hypotensive, tachycardic, cyanotic with generalized skeletal muscle pain, and with paresis of all extremities and hyporeflexia. [thefreelibrary.com] Hepatic Encephalopathy Asterixis Automatisms (eg, yawning, blinking, sucking) 3 Somnolence Confusion Amnesia Anger, paranoia, or other bizarre behavior Nystagmus Muscular rigidity Hyperreflexia or hyporeflexia [merckmanuals.com] […] in motor function may include rigidity, disorders of speech production, resting‐ and movement‐induced tremor, asterixis, delayed diadochocinetic movements, hyperreflexia, hyporeflexia [doi.org] Manifestations include cognitive and behavioral dysfunction (eg, confusion, obtundation, coma) and neuromuscular dysfunction (eg, flapping tremor, ataxia, hyperreflexia or hyporeflexia [merckmanuals.com] Hypokalemia […] resulting hyperpolarization leads to a reduced neuromuscular excitability and thus causes: Muscular adynamia (extreme form: paresis ) Weakening or suspension of reflexes (hyporeflexia [flexikon.doccheck.com] However, in more severe cases, patients can present with muscle weakness, paraesthesia, constipation / ileus or pseudo-obstruction, hypotonia, hyporeflexia, muscle cramps, [teachmesurgery.com] Arachnoiditis Clinical description Patients present with chronic, persistent deafferentiation pain in the lower back, limbs and trunk that is increased by activity, hyporeflexia, loss of [orpha.net] Leptomeningeal Metastasis A case of leptomeningeal metastasis from lung adenocarcinoma is reported. In this case, we evaluated the feasibility of reverse transcriptased polymerase chain reaction (RT-PCR) methods to detect cancer cells in cerebrospinal fluids (CSF). Messenger RNA of carcinoembryonic antigen (CEA) was clearly demonstrated in[…] [ncbi.nlm.nih.gov] Encephalitis As well as the typical symptoms of encephalitis, these patients may also have disturbed vision, difficulty urinating and hyporeflexia. [doi.org] Hypercalcemia Anxiety Psychotic symptoms: hallucination CNS depression, somnolence and eventually coma do occur at high levels Hypotonia and hyporeflexia Can mimic focal neurological lesions [broomedocs.com] […] other non-specific symptoms) Thrones (polyuria) resulting in dehydration due to nephrogenic diabetes insipidus from nephrocalcinosis Muscle tone (hypotonia, muscle weakness, hyporeflexia [en.wikipedia.org] […] channels and inhibits depolarization of nerve and muscle fibers, increased calcium raises the threshold for depolarization.[5] This results in diminished deep tendon reflexes (hyporeflexia [en.wikipedia.org] Acute Intermittent Porphyria Other features include preservation of achilles reflexes while global hyporeflexia and neuropathic or myalgic pain. [ncbi.nlm.nih.gov] Intracranial Hypertension Macaya ARoing MFernrndez JMBoronat M Pseudotumor cerebri, spinal and radicular pain, and hyporeflexia: a clinical variant of the Guillain-Barré syndrome? [jamanetwork.com] an absence of patellar reflexes (hyporeflexia), flushing, and muscle flaccidity. [medical-dictionary.thefreedictionary.com] Sarcoidosis Intern Med. 2017 Oct 1;56(19):2583-2588. doi: 10.2169/internalmedicine.8768-16. Epub 2017 Sep 6. Author information 1 Department of Gastroenterology and Hepatology, Okayama University Graduate School of Medicine, Dentistry and Pharmaceutical Sciences, Japan. 2 Saito Clinic, Japan. 3 Department of General Medicine,[…] [ncbi.nlm.nih.gov] General Anesthesia We report the successful management of general anesthesia for a patient with Pelizaeus-Merzbacher disease (PMD). PMD is one of a group of progressive, degenerative disorders of the cerebral white matter. The typical clinical manifestations of PMD include psychomotor retardation, nystagmus, abnormal muscle tone,[…] [ncbi.nlm.nih.gov] Brachial Plexus Neuritis There is hyporeflexia, neurogenic atrophy and loss of sensation. [medical-dictionary.thefreedictionary.com] Suspect acute brachial neuritis if patients have severe supraclavicular pain, followed by weakness and hyporeflexia that develop within days and resolve over months. [msdmanuals.com]
