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104 Possible Causes for Hyporeflexia in Affected Muscles

  • Limb-Girdle Muscular Dystrophy Type 1G

    LMN signs include weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations. In the early stage of the disease, the clinical aspects of ALS can vary.[aetna.com] UMN signs include hyperreflexia, extensor plantar response, increased muscle tone, and weakness in a topographical representation.[aetna.com] Affected individuals typically present with asymmetric focal weakness of the extremities (stumbling or poor handgrip) or bulbar findings (dysarthria, dysphagia).[aetna.com]

  • Constitutional Anemia due to Iron Metabolism Disorder

    LMN signs include weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations. In the early stage of the disease, the clinical aspects of ALS can vary.[aetna.com] UMN signs include hyperreflexia, extensor plantar response, increased muscle tone, and weakness in a topographical representation.[aetna.com] Affected individuals typically present with asymmetric focal weakness of the extremities (stumbling or poor handgrip) or bulbar findings (dysarthria, dysphagia).[aetna.com]

  • Binswanger Disease

    […] weakness, hyporeflexia, and autonomic changes (e.g., dry mouth); associated with malignancy (particularly small cell lung cancer) in half to ¾ of affected individuals laminar[strokecenter.org] […] antibodies directed against the voltage-gated calcium channels on the presynaptic motor nerve terminal leading to impaired release of acetylcholine and causing proximal muscle[strokecenter.org]

  • Young Adult-Onset Distal Hereditary Motor Neuropathy

    On examination, most patients with CMT exhibit distally dominant weakness, hyporeflexia, and muscle atrophy affecting the legs earlier and more significantly than the arms[emedicine.medscape.com]

  • Myositis

    Disorders associated with generalized muscle weakness can affect bladder function and, in association with decreased urethral sphincter function, may lead to incontinence;[ncbi.nlm.nih.gov] Hyporeflexia is an uncommon finding and may represent a more severe form of myasthenia gravis. The urinary incontinence is also a unique feature.[ncbi.nlm.nih.gov]

  • Motor Neuron Disease

    In the setting of LMN damage, hyporeflexia, atrophy, decreased muscle tone and fasciculations develop, while diseases that affect UMNs cause spasticity, increased muscle tone[symptoma.com]

  • Spinal and Bulbar Muscular Atrophy

    (those of the face and throat).The condition mainly affects males, with onset between the ages of 30 and 60. 0001288 Gynecomastia Enlarged male breast 0000771 Hyporeflexia[rarediseases.info.nih.gov] More Categories: Kennedy disease is a gradually progressive, neuromuscular disorder characterized by wasting of the proximal muscles (those closer to the trunk) and bulbar muscles[rarediseases.info.nih.gov]

  • Autosomal Recessive Lower Motor Neuron Disease with Childhood Onset

    […] atrophy, weakness and hyporeflexia without sensory involvement.[jnnp.bmj.com] They may arise from disease processes affecting the anterior horn cell or the motor axon and/or its surrounding myelin.[jnnp.bmj.com] Neuromuscular junction pathology and muscle disorders may mimic a LMN disorder and form part of the differential diagnosis.[jnnp.bmj.com]

  • Upper Motor Neuron Disease

    […] atrophy, weakness and hyporeflexia without sensory involvement.[jnnp.bmj.com] They may arise from disease processes affecting the anterior horn cell or the motor axon and/or its surrounding myelin.[jnnp.bmj.com] Neuromuscular junction pathology and muscle disorders may mimic a LMN disorder and form part of the differential diagnosis.[jnnp.bmj.com]

  • X-linked Distal Spinal Muscular Atrophy Type 3

    LMN signs include weakness, muscle wasting, hyporeflexia, muscle cramps, and fasciculations. In the early stage of the disease, the clinical aspects of ALS can vary.[aetna.com] UMN signs include hyperreflexia, extensor plantar response, increased muscle tone, and weakness in a topographical representation.[aetna.com] Affected individuals typically present with asymmetric focal weakness of the extremities (stumbling or poor handgrip) or bulbar findings (dysarthria, dysphagia).[aetna.com]

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