De Jarisch-Herxheimerreactie A 73-year-old man presented with fever and hypotension, which had developed a few hours after receiving treatment with benzyl-penicillin for secondary
[ntvg.nl]
Later, there is often vasodilation and decreased peripheral resistance, leading to hypotension.
[cureus.com]
It usually manifests as fever, chills, rigors, nausea and vomiting, headache, tachycardia, hypotension, hyperventilation, flushing, myalgia, and exacerbation of skin lesions
[pubmed.ncbi.nlm.nih.gov]