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347 Possible Causes for Hypothalamic Insufficiency

  • Hypersensitivity

    Standard clinical methods assessed the patient's hypothalamic-pituitary-adrenal axis.[] […] presented for evaluation of adrenal insufficiency prompted by low plasma cortisol levels and multiple unexplained symptoms but without clinical evidence of glucocorticoid insufficiency[]

  • Hypogonadism

    Hypogonadism may be primary due to testicular failure, or secondary due to hypothalamic-pituitary axis dysfunction, resulting in the production or release of insufficient[] Hypogonadism can also result from a combination of testicular failure and hypothalamic-pituitary axis dysfunction.[] Carson III, MD Hypogonadism is defined as deficient or absent male gonadal function that results in insufficient testosterone secretion.[]

  • Adrenal Insufficiency

    To our knowledge, there are no previous case reports discussing the remission of hypothalamic adrenal insufficiency.[] insufficiency; HPA hypothalamic-pituitary-adrenal; OR odds ratio.[] Abstract Background Individuals with Prader-Willi syndrome (PWS) have hypothalamic dysfunction and may have central adrenal insufficiency (CAI).[]

  • Polycystic Ovary Syndrome

    In contrast, women with hypoestrogenic oligo/amenorrhea (due to either ovarian insufficiency [WHO group 3] or hypothalamic-pituitary dysfunction [WHO group 1]) present with[] PCOS is characterized by hypothalamic–pituitary–ovary axis dysfunction and anovulation but, unlike other causes of ovulatory failure that feature insufficient ovarian follicle[]

  • Hyponatremia

    Adrenal insufficiency The hypothalamic–pituitary–adrenal axis (HPAA) can be activated by severe illness and trauma, since HPAA controls the maintenance of homeostasis and[]

  • Pneumonia

    The major theoretical purpose of corticosteroids in sepsis is to restore balance to the altered hypothalamic‐pituitary‐adrenal axis ( Annane 2004 ; Mandell 2015 ).[] In septic shock, a condition of extreme physiological stress, suboptimal cortisol production has been termed critical illness‐related corticosteroid insufficiency (CIRCI)[]

  • Endocrine Dysfunction

    The function of hypothalamic-pituitary-gonad, thyroid, somatotrophic, and adrenal axes was assessed.[] […] due to pituitary or hypothalamic disorder -withdrawal of steroid rx -destroying adrenal cortex Manifestations of Addisons disease -hypoglycemia -hypotension -dehydration[] RESULTS: The most common endocrine dysfunction was ovarian insufficiency (95% of women), followed by an increase in follicle-stimulating hormone in 47% of men, indicating[]

  • Hypothyroidism

    insufficiency.[] This pattern may result from hypothalamic immaturity (particularly in preterm infants, 12% of all newborn infants).[] […] or pituitary dysfunction, and are characterized by inappropriately normal or low levels of TSH relative to insufficient thyroid hormone.[]

  • Sepsis

    The task force coined the term critical illness–related corticosteroid insufficiency to describe the dysfunction of the hypothalamic-pituitary-adrenal axis that occurs during[] Critical illness–related corticosteroid insufficiency is caused by adrenal insufficiency together with tissue corticosteroid resistance and is characterized by an exaggerated[]

  • Liver Cirrhosis

    One was diagnosed with hypocortisolism accompanied by liver cirrhosis while the other had secondary adrenal insufficiency caused by a hypothalamic disorder.[]

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