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475 Possible Causes for Hypothalamic Obesity

  • Craniopharyngioma

    Hypothalamic obesity after treatment for craniopharyngioma is a well-recognized, severe problem.[ncbi.nlm.nih.gov] Hypothalamic obesity, a treatment-resistant condition common to survivors of craniopharyngioma (CP), is strongly associated with a poor quality of life in this population.[ncbi.nlm.nih.gov] However, its efficacy and safety in patients with craniopharyngioma-related hypothalamic obesity remain largely unknown.[ncbi.nlm.nih.gov]

  • ROHHAD Syndrome

    […] with Hypothalamic Dysfunction Hypoventilation and Autonomic Dysregulation (ROHHAD). ( 29543408 ) Graziani A...Giuseppe Stefanini F 2016 13 Rapid-onset obesity with hypothalamic[malacards.org] A Rare Cause of Hypothalamic Obesity, Rohhad Syndrome: 2 Cases.[ncbi.nlm.nih.gov] Twenty-three children with what we are now naming rapid-onset obesity with hypothalamic dysfunction, hypoventilation, and autonomic dysregulation were identified.[doi.org]

  • Obesity

    Thus, DJBS proved to be a promising procedure in the treatment of hypothalamic obesity.[ncbi.nlm.nih.gov] Hypothalamic obesity, a treatment-resistant condition common to survivors of craniopharyngioma (CP), is strongly associated with a poor quality of life in this population.[ncbi.nlm.nih.gov] OBJECTIVE: Craniopharyngiomas (CPs) and their treatment are associated with hypothalamic damage that causes hypothalamic obesity (HO) in 30%-70% of cases.[ncbi.nlm.nih.gov]

  • Adenovirus Infection

    Canine distemper virus may promote obesity in mice by inducing hypothalamic damage ( 1 ).[doi.org] Similarly, Ad-36–induced hypothalamic damage is another possible mechanism that should be investigated.[doi.org] Future experiments should investigate the Ad-36–induced up-regulation of fat cell differentiation as a possible mechanism of Ad-36–induced obesity in monkeys.[doi.org]

  • Lymphoblastic Lymphoma

    Hypothalamic obesity syndrome can affect brain tumor patients following surgical intervention and irradiation.[ncbi.nlm.nih.gov] We describe a novel presentation of hypothalamic obesity syndrome in CNS B-cell lymphoblastic lymphoma, responsive to chemotherapy.[ncbi.nlm.nih.gov] Here we present a case of hypothalamic obesity syndrome as the primary presentation of a toddler found to have CNS B-cell lymphoblastic lymphoma.[ncbi.nlm.nih.gov]

  • Essential Hypertension

    Also, obesity is associated with preserved ability of leptin to activate hypothalamic SOCS-3. 7 In addition, SOCS-3 haploinsufficiency or brain SOCS-3 deficiency increases[doi.org] […] ghrelin on appetite appears mediated by vagal afferents originating in the gastrointestinal tract, this hormone may also directly modulate the neuroendocrine network in the hypothalamic[doi.org] […] leptin sensitivity and protects mice against development of obesity induced by high-fat diet. 8,9 Thus, SOCS-3 appears an important mechanism of leptin resistance, suggesting[doi.org]

  • Metabolic Syndrome

    One study 11 demonstrated that persons with elevated levels of serum cortisol (caused by chronic stress) developed abdominal obesity, insulin resistance, and lipid abnormalities[aafp.org] The investigators concluded that this inappropriate activation of the hypothalamic-pituitary-adrenal axis by stress is responsible for the link between psychosocial and economic[aafp.org]

  • Insulin Resistance

    Hypothalamic obesity: the sixth cranial endocrinopathy. The Endocrinologist. 2002 ; 12 : 210–217.[doi.org] Hypothalamic obesity: the myth of the ventromedial nucleus. Science 182, 488–490 (1973). 82 Leibowitz, S. F.[doi.org] Treatment of obesity by moderate and severe caloric restriction. Results of clinical research trials. Ann. Intern. Med. 119, 688–693 (1993). 6 Kennedy, G. C.[doi.org]

  • Hypogonadism

    Context: Middle-aged and older men ( 50 years), especially those who are obese and suffer from comorbidities, not uncommonly present with clinical features consistent with[ncbi.nlm.nih.gov] […] development) infections, including HIV pituitary disorders inflammatory diseases, including sarcoidosis, tuberculosis, and histiocytosis obesity rapid weight loss nutritional[healthline.com] […] development) infections, including HIV pituitary disorders inflammatory diseases, including sarcoidosis , tuberculosis , and histiocytosis obesity rapid weight loss nutritional[healthline.com]

  • Froehlich's Syndrome

    Hypothalamic obesity refers to obesity that is caused by physical or inborn damage to the hypothalamus.[rarediseases.info.nih.gov] […] of the hypothalamic gland resulting in delayed puberty, small testes, and obesity Froelich's syndrome Adiposogenital dystrophy (disorder) Babinski-Froelich Syndrome Froehlich's[wikidata.org] The symptoms of hypothalamic obesity vary by the cause and include uncontrollable hunger, rapid, excessive weight gain, and a low metabolic rate.[rarediseases.info.nih.gov]

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