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155 Possible Causes for Hypothyroidism, Mutation in the Hereditary Hemochromatosis Gene

  • Hemochromatosis

    Over time, people with hereditary hemochromatosis may develop liver cirrhosis, liver cancer, heart disease, diabetes, arthritis, hypothyroidism, and impotence.[nybloodcenter.org] Hereditary hemochromatosis can be divided into HFE- and non-HFE-related based on genetic mutations in different genes.[ncbi.nlm.nih.gov] […] year-round tan without being in the sun) • osteoarthritis or complaint of pain the first two knuckles of the hands (iron fist)osteoporosis (especially joint replacement) • hypothyroidism[irondisorders.org]

  • Iron Deficiency

    Iron deficiency slows your body's thyroid function and blocks its metabolism-boosting effects, according to the National Academy of Hypothyroidism.[huffpost.com] A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet. 1996;13:399–408. PubMed CrossRef Google Scholar 8.[doi.org] […] have an underactive thyroid url: text: Iron deficiency slows your body's thyroid function and blocks its metabolism-boosting effects, according to the National Academy of Hypothyroidism[abcnews.go.com]

  • Alopecia Areata

    Hypothyroidism can develop in patients with Graves' disease, either spontaneously or as a result of radioactive iodine therapy or surgery.[ncbi.nlm.nih.gov] Hereditary hemochromatosis (HHC) is a common genetic disorder of iron overload, caused by mutations in the HFE gene.[ncbi.nlm.nih.gov] Among the thyroid disorders, hypothyroidism was the most frequent association (14.1%) in our study.[ncbi.nlm.nih.gov]

  • Pseudogout

    Causes of CPPD can be divided into: idiopathic hereditary AD pattern; mutation in the ANKH gene which encodes a transmembrane inorganic pyrophosphate transporter secondary[radiopaedia.org] . - hemochromatosis ; - hyperparathyroidism (most common); - up to 30% of hyperparathyroid pts have chondrocalcinosis; - hypothyroidism ; - gout : - ref: Gout and coexisting[wheelessonline.com] hemochromatosis hyperparathyroidism hypothyroidism hypomagnesemia 2 previous joint injury ochronosis CPPD has many features of osteoarthritis with an unusual distribution[radiopaedia.org]

  • Calcium Pyrophosphate Arthropathy

    . - hemochromatosis ; - hyperparathyroidism (most common); - up to 30% of hyperparathyroid pts have chondrocalcinosis; - hypothyroidism ; - gout : - ref: Gout and coexisting[wheelessonline.com] Causes of CPPD can be divided into: idiopathic hereditary AD pattern; mutation in the ANKH gene which encodes a transmembrane inorganic pyrophosphate transporter secondary[radiopaedia.org] Hypothyroidism, hypomagnesemia , diabetes, and chronic kidney disease did not appear to be associated with the disease.[acrabstracts.org]

  • Hereditary Chondrocalcinosis

    […] approach to hereditary hemochromatosis.[physio-pedia.com] . - hemochromatosis ; - hyperparathyroidism (most common); - up to 30% of hyperparathyroid pts have chondrocalcinosis; - hypothyroidism ; - gout : - ref: Gout and coexisting[wheelessonline.com] […] with acute attacks Pseudo Osteoarthritis without acute attacks Lanthanic (asymptomatic) Hereditary Secondary "WHIP A DOG" Wilson’s Haemochromatosis, Hyperparathyroidism, Hypothyroidism[orthofracs.com]

  • Familial Calcium Pyrophosphate Deposition

    There is good evidence that hereditary hemochromatosis, hyperparathyroidism, and hypomagnesemia predispose to secondary CC.[thehealthscience.com] The patient tested negative for hyperparathyroidism, hemochromatosis, hypophosphatasia, hypomagnesemia, hypothyroidism, familial hypercalciuria, acromegaly, diabetes mellitus[jrheum.org] . - hemochromatosis ; - hyperparathyroidism (most common); - up to 30% of hyperparathyroid pts have chondrocalcinosis; - hypothyroidism ; - gout : - ref: Gout and coexisting[wheelessonline.com]

  • African Iron Overload

    Gene mutations that cause hemochromatosis A gene called HFE is most often the cause of hereditary hemochromatosis. You inherit one HFE gene from each of your parents.[mayoclinic.org] […] iron overload, increases the risk for liver disease (cirrhosis, cancer), heart attack or heart failure, diabetes mellitus, osteoarthritis, osteoporosis, metabolic syndrome, hypothyroidism[blackdoctor.org] Hypothyroidism - as a result of deposition in the thyroid How is iron overload disease diagnosed?[health24.com]

  • Heart Failure

    Cardiovascular signs and symptoms can prevail in both hypothyroidism and hyperthyroidism.[ncbi.nlm.nih.gov] The actuarial survival rates of persons who are homozygous for the mutation of the hemochromatosis gene C282Y have been reported to be 95%, 93%, and 66%, at 5, 10, and 20[doi.org] Chronic diseases — such as diabetes, HIV, hyperthyroidism, hypothyroidism, or a buildup of iron (hemochromatosis) or protein (amyloidosis) — also may contribute to heart failure[mayoclinic.com]

  • Primary Hemochromatosis Type 1

    Two of four siblings with JH also had Hashimoto thyroiditis (hypothyroidism).[irondisorders.org] Have identified at least eight mutations in the HAMP gene that result in juvenile hereditary hemochromatosis or hereditary hemochromatosis type 2.[ivami.com] Irregular heart beat or heart attack Arthritis (osteoarthritis, osteoporosis) Cirrhosis of the liver or liver cancer Gall bladder disease Depression Impotence Infertility Hypothyroidism[hemochromatosis.org]

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