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26 Possible Causes for Hypothyroidism, Myopia, Wide Space Between the First and Second Toe

  • Down Syndrome

    Among the subclinical hypothyroidism group, 25 (73.5%) had transient hypothyroidism and 9 (26.5%) persistent hypothyroidism.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] Nystagmus was related to myopia and esotropia, and to heart disease and heart operations.[oadoi.org]

  • Dubowitz Syndrome

    There can be many associated heath problems including hypothyroidism (an underactive thyroid), heart defects, hypotonia and eye problems.[bertsbigadventure.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] […] eruption of teeth Dry skin High palate Hydrocephalus Hydronephrosis Hypoparathyroidism Hypoplastic toenails Joint hyperflexibility Lymphoma Malabsorption Metatarsus adductus Myopia[dovemed.com]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Thyroid Problems What is hypothyroidism? What causes hypothyroidism? Who gets hypothyroidism? How does hypothyroidism cause disease? What are the common findings?[calvarypediatrics.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] Corneal enlargement Axial myopia Hereditary megalocornea Keratoglobus 3.[entokey.com]

  • Kenny-Caffey Syndrome Type 1

    The following complications may develop in individuals affected by Kenny-Caffey Syndrome Type 1: Dwarfism Secondary hypothyroidism, which can lead to nervousness, muscle cramps[dovemed.com] space between the first and second toes.[medcraveonline.com] Symptoms - Kenny-Caffey syndrome- Type 1 * Tetanic convulsions * Delayed physical development * Myopia * Small eyes * Farsightedness * Swelling of optic disk * Vascular tortuosity[checkorphan.org]

  • Cutis Laxa

    We report a newborn with autosomal recessive form of congenital cutis laxa, who had congenital hypothyroidism owing to isolated thyrotropin deficiency.[ncbi.nlm.nih.gov] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] Features include inelastic skin which sags and may be wrinkly, high myopia, arterial tortuosity, aneurysms, stenosis, joint laxity and arachnodactyly among other clinical[unmc.edu]

  • Atelosteogenesis Type 2

    XY complete gonadal dysgenesis 46,XY partial gonadal dysgenesis Athyreosis Familial gestational hyperthyroidism Familial hyperthyroidism due to mutations in TSH receptor Hypothyroidism[csbg.cnb.csic.es] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] A consanguineous Saudi family with severe and recurrent large joint dislocation and severe myopia, was identified with a homozygous truncating variant in GZF1.[rarediseases.org]

  • Ring Chromosome 10

    […] hypospadia, bifid scrotum, bilateral cryptorchidism, bilateral inguinal hernia, vesico-uretheral reflux (grade III), recurrent pulmonary and urinary infections, subclinical hypothyroidism[biomedsearch.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Patient III . 14 year-old boy, short stature, dolico-trigonocephaly, bilateral epicanthic folds, upslanting palpebral fissures, ocular hypertelorism, left palpebral ptosis, myopia[biomedsearch.com]

  • Kleiner Holmes Syndrome

    Maternal antenatal history was uneventful except for subclinical hypothyroidism detected during gestation.[docksci.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] […] and Distinctive Facial Features cleft palate-lateral synechia syndrome cleft soft palate Cleidorhizomelic Syndrome CLOVES syndrome COACH Syndrome Cochlear Deafness with Myopia[rgd.mcw.edu]

  • Short Stature due to Endocrine Disorder

    […] insulin-like growth factor type 1 deficiency Growth hormone insensitivity syndrome Laron syndrome Laron syndrome with immunodeficiency MULIBREY nanism Parastremmatic dwarfism Rare hypothyroidism[se-atlas.de] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] 0001943 Low anterior hairline Low frontal hairline Low-set frontal hairline [ more ] 0000294 Low posterior hairline Low hairline at back of neck 0002162 Motor delay 0001270 Myopia[rarediseases.info.nih.gov]

  • Seckel Syndrome

    Synonym: pituitary dwarf. (05 Mar 2000) hypothyroid dwarf Dwarfism associated with lack of thyroid function. (05 Mar 2000) oil of dwarf pine needles Volatile oil from the[kmle.co.kr] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] RESULTS: Severe bilateral pigmentary retinopathy with severe myopia and astigmatism was found in all three patients.[ncbi.nlm.nih.gov]

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