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31 Possible Causes for Hypothyroidism, Wide Space Between the First and Second Toe

  • Down Syndrome

    Clinicians should be aware of the increased risk of gallstones in hypothyroid children with DS, even in neonatal age.[ncbi.nlm.nih.gov] A wide space, often with a deep fissure between the first and second toes, is also common.[dx.doi.org] spacing, often with a deep plantar groove between the first and second toes.[doi.org]

  • Dubowitz Syndrome

    There can be many associated heath problems including hypothyroidism (an underactive thyroid), heart defects, hypotonia and eye problems.[bertsbigadventure.org] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] In older patients, endocrine problems were common: hypogonadism, hypothyroidism, amenorrhea, and diabetes ( Table S5 ).[journals.plos.org]

  • Atelosteogenesis Type 2

    XY complete gonadal dysgenesis 46,XY partial gonadal dysgenesis Athyreosis Familial gestational hyperthyroidism Familial hyperthyroidism due to mutations in TSH receptor Hypothyroidism[csbg.cnb.csic.es] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Deficiency Hunter Syndrome (MPS II) Hypochondrogenesis Hurler-Scheie Syndrome (MPS I) Hypochondroplasia Hypophosphatemia Hypophosphatasia Hypopituitary Jarcho-Levin Syndrome Hypothyroidism[epainassist.com]

  • Ring Chromosome 10

    […] hypospadia, bifid scrotum, bilateral cryptorchidism, bilateral inguinal hernia, vesico-uretheral reflux (grade III), recurrent pulmonary and urinary infections, subclinical hypothyroidism[biomedsearch.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

  • Kleiner Holmes Syndrome

    Maternal antenatal history was uneventful except for subclinical hypothyroidism detected during gestation.[docksci.com] […] gap between first and second toes Wide space between 1st, 2nd toes Wide space between first and second toes Widely spaced 1st-2nd toes Widely spaced first and second toes[rarediseases.info.nih.gov] […] muscular of Guam alopecia pseudohy per trophy and Amyotrophic lateral sclerosis- Metaphyseal chondrodysplasia with Blepharophimosis syndrome type 2 Eosinophilic esophagitis hypothyroidism[yumpu.com]

  • Growth Delay due to Insulin-Like Growth Factor I Resistance

    […] insulin-like growth factor type 1 deficiency Growth hormone insensitivity syndrome Laron syndrome Laron syndrome with immunodeficiency MULIBREY nanism Parastremmatic dwarfism Rare hypothyroidism[se-atlas.de] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] This insensitivity may be primary (genetic) or secondary to conditions such as malnutrition, hypothyroidism, sex hormone deficiency, and chronic diseases.[labtestsonline.org]

  • Familial Congenital Nasolacrimal Duct Obstruction

    Thyroid Problems What is hypothyroidism? What causes hypothyroidism? Who gets hypothyroidism? How does hypothyroidism cause disease? What are the common findings?[calvarypediatrics.com] space between first and second toes (sandal toes) clinodactyly of the fifth finger All of these are found in individuals without DS.[medicalhomeportal.org] […] on Familial Exudative Vitreoretinopathy, Autosomal Dominant Cell surface receptor deficiencies G protein-coupled receptor (including hormone ) Class A TSHR ( Congenital hypothyroidism[ipfs.io]

  • Cutis Laxa

    We report a newborn with autosomal recessive form of congenital cutis laxa, who had congenital hypothyroidism owing to isolated thyrotropin deficiency.[ncbi.nlm.nih.gov] Other reported osteoarticular features are: a wide space between the first and second toes; talipes equinovarus; metatarsus adductus; genu recurvatum or genu valgum; flat[scielo.br] In hypothyroid subjects, the skin is dry, cold, and rough. The epidermis is hyperkeratotic, alopecia may develop, and there is diffuse myxedema [ 7 ].[karger.com]

  • Kenny-Caffey Syndrome Type 1

    The following complications may develop in individuals affected by Kenny-Caffey Syndrome: Dwarfism Secondary hypothyroidism, which can lead to nervousness, muscle cramps,[dovemed.com] space between the first and second toes.[medcraveonline.com] The following complications may develop in individuals affected by Kenny-Caffey Syndrome Type 1: Dwarfism Secondary hypothyroidism, which can lead to nervousness, muscle cramps[dovemed.com]

  • Craniofrontonasal Dysplasia

    […] syndrome 1B Endothelin EDN3 Waardenburg syndrome IVb Hirschsprung's disease 4 Other DHH ( DHH XY gonadal dysgenesis ) BMP15 ( Premature ovarian failure 4 ) TSHB ( Congenital hypothyroidism[maria-online.com] 1st and 2nd toes Gap between first and second toe Increased space between first and second toes Sandal gap between first and second toes Wide space between 1st, 2nd toes[rarediseases.info.nih.gov] Wide space between first and second toes Wide-spaced big toe Widely spaced 1st-2nd toes Widely spaced first and second toes Widened gap 1st-2nd toes Widened gap first and[rarediseases.info.nih.gov]

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