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135 Possible Causes for Hypoxia, Lactate Dehydrogenase Increased, Neutrophil Count Increased

  • Acute Pancreatitis

    dehydrogenase – AST – During initial 48 hrs Hematocrit decrease – BUN increase – Serum calcium – Base deficit – Fluid sequestration – PaO2 – AST aspartate aminotransferase[arupconsult.com] Many people develop hypoxia, which means that cells and tissues are not receiving enough oxygen. Doctors treat hypoxia by giving oxygen through a face mask.[wakegastro.com] Complete blood count: Demonstrates the acuteness of the disease while the neutrophil to lymphocyte ratio is valuable a predictor of pancreatitis prognosis.[symptoma.com]

  • Acute Myocardial Infarction

    The Pathophysiology of Myocardial Infarction Myocardial infarction ("heart attack") is the irreversible damage of myocardial tissue caused by prolonged ischemia and hypoxia[cvpharmacology.com] […] severe anemia Aortic dissection, with retrograde involvement of the coronary arteries Respiratory infections, particularly influenza [23, 24] In addition, MI can result from hypoxia[emedicine.medscape.com] […] severe anemia Aortic dissection , with retrograde involvement of the coronary arteries Respiratory infections, particularly influenza [23, 24] In addition, MI can result from hypoxia[emedicine.medscape.com]

  • Pulmonary Embolism

    Hypoxia is an independent predictor of both right ventricular dysfunction and 30-day mortality in these patients.[ncbi.nlm.nih.gov] CONCLUSIONS Tracheobronchomalacia should be considered in the differential diagnosis of hypoxia when evaluating a patient in the ICU.[ncbi.nlm.nih.gov] PRESENTATION: A nine-year-old female with spinal muscular atrophy type 1, chronic respiratory failure with tracheostomy and ventilator dependence presented with tachypnea and hypoxia[ncbi.nlm.nih.gov]

  • Sickle Cell Disease

    We show that ( i ) hypoxia significantly enhances sickle RBC adherence; ( ii ) HbS polymerization enhances sickle cell adherence in SRs and SMEs, but not in ISCs; ( iii )[ncbi.nlm.nih.gov] During hydroxyurea treatment, the white-cell count, absolute neutrophil count, and absolute reticulocyte count significantly decreased, reflecting the intended mild bone marrow[doi.org] We present the unusual case of complete neurologic survival after prolonged hypoxia, severe acidosis, out of hospital cardiac arrest, and exposure to high levels of carbon[ncbi.nlm.nih.gov]

  • Sickle Cell Crisis

    Endothelin-1 (ET-1) is a potent vasoconstrictor and mitogen secreted in response to hypoxia.[ncbi.nlm.nih.gov] Types of sickle cell disease sickle cell anemia (usually homozygous SS genotype) sickle beta thalassemia sickle HbC disease PRECIPITANTS Commonly: infection dehydration hypoxia[lifeinthefastlane.com] […] reticulocytes, bilirubin, hemolytic screen and cross-match blood film: sickle cells and evidence of hemolysis (e.g. target cells, schistocytes) MANAGEMENT Resuscitation correct hypoxia[lifeinthefastlane.com]

  • Pulmonary Infarction

    Pulmonary embolism and myocardial hypoxia during extracorporeal membrane oxygenation. J Pediatr Surg. 1999 Mar. 34(3):485-7. [Medline]. Kossoff EH, Poirier MP.[emedicine.medscape.com] […] ectopic, occult trauma) Basics: ABCs, IV, O 2 , Cardiac Monitor and 12-lead EKG Airway, Breathing Circulation Intubation may be necessary if the patient has significant hypoxia[coreem.net] […] that does not respond to supplemental O 2 or has respiratory fatigue This is likely to be a physiologically difficult airway Baseline hypoxia makes the risk of critical desaturation[coreem.net]

  • Hepatocellular Carcinoma

    dehydrogenase, inhibited cell migration, and enhanced the apoptosis rate in HepG2 and PLC/PRF/5 cells. 5h2c led to an increase in intracellular reactive oxygen species levels[ncbi.nlm.nih.gov] We observed that hypoxia-induced YAP activation is crucial for accelerating HCC cell glycolysis.[ncbi.nlm.nih.gov] It was proposed that hypoxia leads to an increase in a transcriptional factor called Hypoxia-inducible factor-1 (HIF-1) which plays an important role in the breakthrough of[cureus.com]

  • Disseminated Intravascular Coagulation

    Plasma exchange only improved lactate dehydrogenase levels. We clinically diagnosed this case as atypical HUS and started eculizumab treatment.[ncbi.nlm.nih.gov] […] including transfusion reaction, drug induced hemolysis, and Paroxysmal nocturnal hemoglobinuria Vascular malformation and aneurysms Massive tissue injury (includes trauma) Hypoxia[clevelandclinicmeded.com] RESULTS: Endothelial-derived CD105-MPs, leucocyte-derived CD11a-MPs/leucocyte, and neutrophil-derived CD66b-MPs/neutrophil count ratios significantly increased in DIC compared[ncbi.nlm.nih.gov]

  • Eclampsia

    Her biochemical analysis showed a decrease in total protein and an increase in alanine transaminase (ALT) and lactate dehydrogenase (LDH) and high serum uric acid and hyperlipidemia[ncbi.nlm.nih.gov] Prolonged exposure to hypoxia endangers the health of the fetus and the mother and is the primary reason premature delivery may be necessary in preeclamptic pregnancies.[britannica.com] lactate dehydrogenase (LDH) levels.[glowm.com]

  • Myeloproliferative Disease

    Proposed revised WHO criteria for primary myelofibrosis: Minor criteria:  Leukoerythroblastosis  Increase in serum lactate dehydrogenase level  Anemia  Palpable splenomegaly[slideshare.net] Secondary PolycythemiaSecondary PolycythemiaAppropriate EPO (tissue/kidney hypoxia)Appropriate EPO (tissue/kidney hypoxia)pulmonary diseasepulmonary diseasehigh altitudehigh[slideshare.net] Main feature: gradual increase in leukocyte count See too many neutrophils at various stages of maturation, granulocytosis with all granulocytic precursors, and there is characteristic[quizlet.com]

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