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29 Possible Causes for Hypoxia, Peripheral T Cells Decreased, Pertussis

  • Asthma

    Bordetella pertussis positive individuals had lower FEV 1 /FVC (77.1% v 80.7%, p   0.012) and more asthma symptoms than B pertussis negative cases.[dx.doi.org] Vasoconstriction due to alveolar hypoxia also contributes to this mismatch. Vasoconstriction is also considered an adaptive response to ventilation/perfusion mismatch.[emedicine.medscape.com] RT‑qPCR demonstrated that VDR expression in the peripheral blood of asthmatic children was decreased.[ncbi.nlm.nih.gov]

  • Influenza

    OBJECTIVES: Influenza and pertussis vaccination programmes have been in place for pregnant women in the UK since 2009 and 2012, respectively.[ncbi.nlm.nih.gov] […] some or all of the following findings: Fever of 100-104 F; fever is generally lower in elderly patients than in young adults Tachycardia, which most likely results from hypoxia[emedicine.medscape.com] In contrast, IL-1R1 / mice showed a dramatic decrease in CD4 T-cell proliferation, suggesting that efficient T-helper cell priming in peripheral organs is dependent on a functional[dx.doi.org]

  • Graves Disease

    Berbers and Anne-Marie Buisman , Whole-cell or acellular pertussis vaccination in infancy determines IgG subclass profiles to DTaP booster vaccination , Vaccine , 36 , 2 ,[doi.org] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] We aim to study the expression of PDGF-BB, hypoxia inducible factor (HIF)-1α and C-C motif chemokine receptor (CCR)-2 in peripheral blood of patients with GD and explore its[ncbi.nlm.nih.gov]

  • Guillain-Barré Syndrome

    Yih WK, Nordin JD, Kulldorff M, Lewis E, Lieu TA, Shi P, Weintraub ES: An assessment of the safety of adolescent and adult tetanus-diphtheria-acellular pertussis (Tdap) vaccine[oadoi.org] Atelectasis leads to hypoxia. ii. Hypercarbia later finding; arterial blood gases may be misleading. iii.[physio-pedia.com] The percentages of Th1 and Th17 cells in the CD4 T lymphocyte subsets were significantly decreased, whereas the Th2 and Treg cells were increased in patients after treatment[ncbi.nlm.nih.gov]

  • Adenovirus Infection

    "Guard Against Pertussis." Contemporary Pediatrics (February 2003): 87. Kolavic-Gray, Shellie A., et al.[medical-dictionary.thefreedictionary.com] Appearance of virus-specific CD4 T cells in peripheral blood and a rise of neutralizing antibody titres specific for the HAdV serotype infecting the patient could be demonstrated[nature.com] However, there was no hypoxia and there were no new radiologic changes in the lungs, and hence this was qualified as upper respiratory illness only.[bloodjournal.org]

  • Haddad Syndrome

    […] beclomethasone, fluticasone) Hyperimmune globulins (eg, varicella-zoster immune globulin) Immunizations (eg, vaccines, including diphtheria and tetanus toxoids [DT or Td], acellular pertussis[emedicine.medscape.com] Children with Haddad syndrome begin with hypoxia that develops in the first few hours of birth and intestinal transit problems in the subsequent days.[actapediatrica.org.mx] In contrast, immune cells in patients with TINU syndrome have a paradoxical suppression of cytokine production and a decrease in peripheral immune response, as demonstrated[uptodate.com]

  • Essential Hypertension

    This splice variant may be responsible for the enhanced signal transduction via pertussis toxin–sensitive G proteins previously observed in lymphoblasts and fibroblasts from[doi.org] […] leptin levels Elevated von Willebrand factor Physiologic responses Increased chemoreceptor sensitivity as seen by exaggerated pressor response and ventilation response to hypoxia[aafp.org] RESULTS: Compared with non-H-type hypertensive patients, CD4 T-cell percentage in peripheral blood was significantly decreased in H-type hypertensive patients.[ncbi.nlm.nih.gov]

  • Preterm Labor

    […] chloroquine, ChQ) reverses the rise in intracellular Ca 2 concentration ([Ca 2 ] i ) and cell shortening induced by uterotonics, and this reversal effect is inhibited by pertussis[ncbi.nlm.nih.gov] But nifedipine is associated with an increased risk of angina, heart attack, congestive heart failure, irregular heart rhythm, oxygen deficiency in the tissues (hypoxia),[consumerreports.org] cells in peripheral blood was significantly decreased.[ncbi.nlm.nih.gov]

  • Alcoholic Liver Disease

    Immune AIDS and HIV Viral Hepatitis Infectious Disease Influenza Measles, Mumps, and Rubella Pneumonia Sexually Transmitted Diseases (STD) Chronic Sinusitis Whooping Cough or Pertussis[cdc.gov] More pronounced fatty liver Less induction of fatty acid binding protein (higher FFA) Increased plasma endotoxin levels Increased CD 13 More severe pericentral hypoxia More[slideshare.net] Peripheral Blood CD4 /CD25 Regulatory T Cells in Patients with Alcoholic Hepatitis, Alcoholism: Clinical and Experimental Research, 37, 8, (1361-1369), (2013).[doi.org]

  • Lymphocytopenia

    Witvliet MH, Vogel ML, Wiertz EJ, Poolman JT: Interaction of pertussis toxin with human T lymphocytes. Infect Immun 60:5085, 1992. 58.[medtextfree.wordpress.com] Acute hypoxia and hypoxic exercise induce DNA strand breaks and oxidative DNA damage in humans. FASEB J. 2001;15:1181-6. 22.[ms-se.com] Flow cytometry immunophenotyping of peripheral blood lymphocytes was investigated in order to analyze monoclonality of B or T cells and showed a decreased ratio of the CD4[pubs.sciepub.com]

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