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619 Possible Causes for Hypoxia, Tinnitus

  • Myeloproliferative Disease

    Secondary PolycythemiaSecondary PolycythemiaAppropriate EPO (tissue/kidney hypoxia)Appropriate EPO (tissue/kidney hypoxia)pulmonary diseasepulmonary diseasehigh altitudehigh[slideshare.net] […] myeloid metaplasia Easy bruising, bleeding, and/or symptoms of thrombosis Swollen, painful joint(s) secondary to gouty arthritis that is secondary to hyperuricemia Priapism, tinnitus[emedicine.com]

  • Carbon Monoxide Poisoning

    Treatment is directed toward the relief of tissue hypoxia and the removal of CO from the body.[ncbi.nlm.nih.gov] This reduces the usual ready O2 release in the tissue and is a major factor in the production of CNS hypoxia and damage.[archive.rubicon-foundation.org] CO toxicity is the result of a combination of tissue hypoxia-ischemia secondary to carboxyhemoglobin formation and direct CO-mediated damage at a cellular level.[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    While hypoxia has been demonstrated in some patients with polycythemia vera (4-6) it has been attributed in these instances to co-existent cardiorespiratory disease (1, 6)[annals.org] Polycythemia Vera Signs and symptoms Symptoms related to expanded blood volume and increased viscosity Headache, tinnitus, dizziness, blurred vision, TIAs, and fatigue Generalized[slideshare.net] Clinical description Symptoms are often insidious at onset and may include headache, dizziness, vertigo, tinnitus, visual disturbances, and pruritus after bathing, a ruddy[orpha.net]

  • Anemia

    Because red blood cells (as hemoglobin) carry oxygen, a decreased production or number of these cells result in "hypoxia."[chop.edu] Tinnitus This is extremely common in patients with PA and is probably due to slight nerve damage to the brain.[pernicious-anaemia-society.org] In states of hypovolemic hypoxia, the increased venous tone due to sympathetic discharge is thought to dominate the vasodilator effects of hypoxia.[web.archive.org]

  • Von Hippel-Lindau Disease

    […] pVHL, the protein product of the von Hippel-Lindau (VHL) tumor suppressor gene, is a ubiquitin ligase that targets hypoxia-inducible factor α (HIF-α) for proteasomal degradation[ncbi.nlm.nih.gov] In 1960, a 24-year-old woman presented with unilateral hearing loss, pulsatile tinnitus and a mass visible on otoscopy.[ncbi.nlm.nih.gov] VHL acts as a tumor suppressor, mainly through the negative regulation of hypoxia-inducible factors.[ncbi.nlm.nih.gov]

  • Acoustic Trauma

    The rationale of administering oxygen to patients with AAT is based on experimental studies showing that noise exposure results in cochlear hypoxia, which could be compensated[ncbi.nlm.nih.gov] The most effective masking of the tinnitus due to acoustic trauma was by pure tones.[ncbi.nlm.nih.gov] Acute acoustic trauma (AAT) is a sensorineural hearing impairment due to exposure to an intense impulse noise which causes cochlear hypoxia.[ncbi.nlm.nih.gov]

  • Head Injury

    Hypoxia and hypotension accounts for the majority of secondary insults associated with traumatic head injuries.[symptoma.com] Huffing American Tinnitus Assoc: Ringing in the ears - Information, resources and support.[headinjury.com] Possible causes of widespread brain damage include birth hypoxia, prolonged hypoxia (shortage of oxygen), poisoning by teratogens (including alcohol), infection, and neurological[en.wikipedia.org]

  • Presbycusis

    Second, increased blood viscosity could induce tissue hypoxia by decreasing capillary blood flow and oxygen transport.[doi.org] […] with tinnitus become crucial.[ncbi.nlm.nih.gov] In patients with unilateral sensorineural hearing loss and tinnitus, fitting the impaired ear is sufficient.[ncbi.nlm.nih.gov]

  • Hypertension

    Here Dabral et al. describe a RASSF1a-HIF-1α feedforward loop driving the Warburg effect both in a mouse model of hypoxia-induced pulmonary hypertension and a subset of human[nature.com]

  • Secondary Polycythemia

    The expression of hypoxia-inducible factor (HIF)-1α, which is undetectable in normal kidney, was observed in the renal tubule epithelium compressed by lymphoblastic cells.[ncbi.nlm.nih.gov] Confusion and ringing in the ears ( tinnitus ) may also occur.[doctor-clinic.org] Chronic hypoxia has been implicated in the pathogenesis of NBTE in both human and animal studies.[sciedupress.com]

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