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290 Possible Causes for Hypsarrhythmia

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  • Early Myoclonic Encephalopathy

    Evolve to hypsarrhythmia and then to diffuse slow spike waves Transformation Persists for long period Evolves to West syndrome and then to Lennox-Gastaut syndrome Epidemiology[] As infants develop, the EEG may evolve to a hypsarrhythmia pattern, which is the term for an EEG with multifocal high amplitude spikes with a very abnormal background.[] At three months of age the baby developed spasms with no hypsarrhythmia. Throughout his infancy, he had small myoclonic jerks and is severely impaired.[]

  • West Syndrome

    West syn·drome ( west ), an encephalopathy in infancy characterized by infantile spasms, arrest of psychomotor development, and hypsarrhythmia.[] Example of hypsarrhythmia CAUTION Hypsarrhythmia may not be present early after the onset of epileptic spasms. The EEG may need to be repeated.[] Similarly, some children with infantile spasms never exhibit hypsarrhythmia.[]

  • Lennox-Gastaut Syndrome

    There is also a tendency for psychosis to develop with time. 20% of all patients with Lennox-Gastaut syndrome have prior infantile spasms with hypsarrhythmia. [ 3 ] Although[] This condition often evolves to West syndrome with infantile spasms and a chaotic EEG pattern (hypsarrhythmia) at 4-8 months of age.[]

  • Myoclonic-Astatic Epilepsy

    Infantile spasms (West syndrome) West syndrome usually occurs in the first year of life and consists of the triad of infantile spasms, developmental deterioration, and a hypsarrhythmia[]

  • Myoclonic Epilepsy of Infancy

    In the vast majority, this pattern is hypsarrhythmia- a very chaotic looking EEG with high amplitude brain waves.[] Other terms currently in usage are "infantile spasms," "hypsarrhythmia" and "massive myoclonic seizures." 2. Myoclonic epilepsy of older children.[] Infants have epileptic (infantile) spasms, developmental regression around 4-6 months of age, and the EEG shows hypsarrhythmia pattern.[]

  • Neurofibromatosis Type 1

    The EEG findings can vary from normal to focal or multifocal spike waves, spike and slow spike wave complexes at 2 Hz consistent with Lennox-Gastaut syndrome , and even a hypsarrhythmia[]

  • D-Glyceric Aciduria

    EEG revealed multifocal generalized epileptic activity in a hypsarrhythmia pattern. Organic acid analysis (GC-MS) in urine revealed increased glyceric acid excretion.[]

  • 6-Pyruvoyl-Tetrahydropterin Synthase Deficiency

    0002015 Excessive salivation Mouth watering Oversalivation Watery mouth [ more ] 0003781 Falls 0002527 Global developmental delay 0001263 Hyperkinesis Muscle spasms 0002487 Hypsarrhythmia[]

  • 10q22.3q23.3 Microdeletion Syndrome

    Prominent nose 10% Abnormality of the dentition 10% Hypospadias 10% Multifocal seizures 10% Hyperventilation 10% Poor eye contact 10% Full cheeks 10% Inability to walk 10% Hypsarrhythmia[]

  • Miller Dieker Syndrome

    Approximately 80 % have infantile spasms; however, the EEG does not show typical hypsarrhythmia in some patients [ 4 ].[] Electroencephalography indicated frequent multifocal independent spikes, sharp waves, and early features of evolving hypsarrhythmia.[] She had an epileptic encephalopathy with infantile spasms (West syndrome) with a typical hypsarrhythmia pattern on her electroencephalogram (EEG).[]

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