Possible Causes for idiopathic hypercalciuria Idiopathic Hypercalcuria Who gets Idiopathic Hypercalciuria? [dovemed.com] What is idiopathic hypercalciuria? Idiopathic hypercalciuria is the excessive excretion of calcium in the urine without obvious cause. [patientslikeme.com] Abstract: Idiopathic Hypercalciuria (IH), a heterogenous disorder, is the most common cause of urolithiasis in children. [eurekaselect.com] Nephrolithiasis hypercalciuria, renal hypophosphatemia, renal tubular acidosis, idiopathic infantile hypercalcemia, Dent disease, familial hypomagnesemia with hypercalciuria and nephrocalcinosis [ncbi.nlm.nih.gov] HHRH may be an underdiagnosed condition that can masquerade as idiopathic hypercalciuria or osteopenia. [ncbi.nlm.nih.gov] Bone disease in idiopathic hypercalciuria. Curr Opin Nephrol Hypertens 2006;15:394-402. [Pubmed] [revistanefrologia.com] Nephrocalcinosis hypercalciuria, renal hypophosphatemia, renal tubular acidosis, idiopathic infantile hypercalcemia, Dent disease, familial hypomagnesemia with hypercalciuria and nephrocalcinosis [ncbi.nlm.nih.gov] Similar, albeit less severe, biochemical changes are observed in heterozygous (het) carriers and indistinguishable from those changes encountered in idiopathic hypercalciuria [ncbi.nlm.nih.gov] Idiopathic hypercalciuria 2. MSK 3. dRTA 4. Hypercalcemic conditions 5. Papillary Necrosis 6. Dent’s Disease 7. [slideshare.net] Urolithiasis Hypercalciuria in a patient with normal serum calcium may be considered idiopathic. [ncbi.nlm.nih.gov] Autosomal dominant: idiopathic hypercalciuria Autosomal recessive Cystinuria, Lesch-Nyhan syndrome, hyperoxaluria types I and II Ehlers-Danlos syndrome, Marfan syndrome, Wilson [unboundmedicine.com] Effects of lowcalcium diet on urine calcium excretion, parathyroid function and serum 1,25(OH)2D3 levels in patients with idiopathic hypercalciuria and in normal subjects.Am [ajkd.org] Hereditary Hypophosphatemic Rickets with Hypercalciuria Similar albeit less severe biochemical changes are also observed in heterozygous carriers, which are furthermore indistinguishable from those encountered in idiopathic hypercalciuria [ncbi.nlm.nih.gov] Stappleton FB: Idiopathic hypercalciuria: Association with isolated hematuria and risk for urolithiasis in children. Kidney Int 1990;37:807–811. [karger.com] As recently shown, heterozygous SLC34A3/NPT2c mutations are frequently associated with idiopathic hypercalciuria (IH), which may cause nephrocalcinosis and kidney stones. [asbmr.org] Hyperuricosuria Abstract Two hundred two recurrent calcium oxalate stone-forming patients with idiopathic hypercalciuria or hyperuricosuria, or both, were treated for an average of 2.91 years [annals.org] Abstract Objective To estimate dietary protein intake in children with idiopathic hypercalciuria (HC) and/or hyperuricosuria (HU). [jpurol.com] Chronic reversal of idiopathic hypercalciuria and hyperuricosuria with thiazide and allopurinol is an effective way to prevent recurrent calcium oxalate stones. [annals.org] Hypercalcemic Nephropathy Idiopathic hypercalciuria 2. MSK 3. dRTA 4. Hypercalcemic conditions 5. Papillary Necrosis 6. Dent’s Disease 7. [slideshare.net] Hypercalciuria: Altered renal tubular handling - eg, idiopathic hypercalciuria, distal renal tubular acidosis (is associated with low urinary excretion of citrate), hypothyroidism [patient.info] Oetliker Idiopathic hypercalciuria with bilateral macular colobomata: A new variant of oculo-renal syndrome Helv Pediat Acta, 34 (1979), pp. 257-269 [15.] R.A. [analesdepediatria.org] Autosomal Dominant Primary Hypomagnesemia with Hypocalciuria Noronha Bone involvement in idiopathic hypercalciuria Clin Nephrol, 57 (2002), pp. 183-191 [19.] E.N. Liatsikos, G.A. [apcontinuada.com] hypercalciuria Immobility Leukemia Lowe's syndrome Lymphoma McCune-Albright syndrome Medullary cystic kidney disease Medullary sponge kidney Metaphyseal chondrodysplasia [wikidoc.org] Hereditary Hypophosphatemic Rickets, X-Linked Recessive Hypouricemia, Hypercalcinuria, And Decreased Bone Density Idiopathic Hypercalciuria Intrauterine Growth Retardation [familydiagnosis.com] Vitamin D Deficiency Idiopathic hypercalciuria and nephrolithiasis. In: Vitamin D. Feldman D, Pike JW, Glorieux FH, ed. New York, Elsevier Press Inc. 2005:1339-1354. 33. Fleet JC. [dr-gahlen.de] Renal Colic New insights into the pathogenesis of idiopathic hypercalciuria. Semin Nephrol 2008;28:120–32. Correspondence afp@racgp.org.au [racgp.org.au] New insights into the pathogenesis of idiopathic hypercalciuria. Semin Nephrol 2008;28:120–32. [racgp.org.au] Idiopathic hypercalciuria is treated with bendroflumethiazide. Frequent urination: This keeps the level of toxins down and prevents the formation of kidney stones. [symptoma.com] High Calcium Diet Pyridoxal phosphate has all the features of suppressing such risk factors for stone formation in patients with idiopathic hypercalciuria. [ncbi.nlm.nih.gov] Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. [ods.od.nih.gov] hypercalciuria. [ncbi.nlm.nih.gov] Renal Tubular Acidosis In other cases familial idiopathic hypercalciuria causes nephrocalcinosis and nephrolithiasis resulting in distal tubular damage and type I renal tubular acidosis. [ncbi.nlm.nih.gov] Intrinsic renal causes: Nephrocalcinosis: Hyperparathyroidism, hypervitaminosis D, milk-alkali syndrome, hyperoxaluria, idiopathic hypercalciuria, etc. [lecturio.com] Hypercalciuria appears to have 2 causes. It may be due to metabolic acidosis, usually in children with a hereditary defect in urine acidification. [ncbi.nlm.nih.gov] Renal Pelvic Calculus Peripheral blood monocyte vitamin D receptor levels are elevated in patients with idiopathic hypercalciuria. J Clin Endocrinol Metab 2004;89:4937–43. 29. [jsms.sch.ac.kr] In most instances, no specific cause can be identified, although most patients have idiopathic hypercalciuria without hypercalcemia. [radiopaedia.org] myelomatosis, renal tubular acidosis, prolonged immobilization, idiopathic hypercalciuria – a) excessive absorption of calcium from gut. b) reduced renal tubular absorption [homeobook.com] Idiopathic Hypercalcemia In conclusion, we suggest that molecular testing for CYP24A1 and SLC34A1 mutations should be performed in each case of idiopathic hypercalcemia/hypercalciuria, both in children [ncbi.nlm.nih.gov] Despite the above prophylaxis, the 25-OHD concentration maintained within high/normal limits, and laboratory data showed a tendency to hypercalcemia, hypercalciuria, and relatively [link.springer.com] […] hypercalcemia, hypercalciuria and suppressed parathormon (PTH). [doi.org] Urate Kidney Stone The remaining 95% of calcium stones are idiopathic. Idiopathic hypercalciuria (IH) is identified in up to 50% of calcium stone formers. [consultant360.com] In most instances, no specific cause can be identified, although most patients have idiopathic hypercalciuria without hypercalcemia. [radiopaedia.org] Idiopathic hypercalciuria, with a prevalence rate ranging from 2.9–6.5%, is defined as increased urinary calcium excretion in patients with an unrestricted calcium diet and [aacc.org] Osteoporosis hypercalciuria Rheumatologic diseases - Rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus Hematologic disease - Multiple myeloma, thalassemia, leukemia [web.archive.org] Urine calcium excretion predicts bone loss in idiopathic hypercalciuria. Kidney Int 2006;70:1463–1467. Girón-Prieto MS, Cano-García M, Poyatos-Andújar A, et al. [betterbones.com] Am J Clin Nutr 2000 ; 72 : 168 – 73. 41 Acute effects of moderate dietary protein restriction in patients with idiopathic hypercalciuria and calcium nephrolithiasis. [doi.org] Familial Renal Glucosuria It is likely that a similar mechanism accounts for the idiopathic hypercalciuria in children with diabetes mellitus. [ncbi.nlm.nih.gov] Hypoparathyroidism and Pseudohypoparathyroidism By B CouR 899 d Differential Diagnosis of Hypercalciuria 929 References 946 Tissue Hormones By A LABHART With Contributions [books.google.de] During the past 5 years, we have identified idiopathic hypercalciuria in five of seven patients referred for evaluation of renal glycosuria between 1985 and 1991. [ncbi.nlm.nih.gov] Disorder of Sulfur-Bearing Amino Acid Metabolism Idiopathic hypercalciuria E83.8 Other disorders of mineral metabolism E83.9 Disorder of mineral metabolism, unspecified E84 Cystic fibrosis. [emprocell.com] hypercalciuria ( E 84 ) Cystic fibrosis ( E 85 ) Amyloidosis ( E 850 ) Non- neuropathic heredofamilial amyloidosis Familial Mediterranean fever ( E 86 ) Volume depletion [psychology.wikia.com] hypercalciuria ( E84 ) Cystic fibrosis ( E85 ) Amyloidosis ( E85.0 ) Non- neuropathic heredofamilial amyloidosis Familial Mediterranean fever ( E86 ) Volume depletion Dehydration [wikidoc.org] Ureterolithiasis The stone fragments were sent to analysis and the patient is currently attending a nephrologist for clinical control of idiopathic hypercalciuria. [casesjournal.biomedcentral.com] Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med. 2002 Jan 10. 346(2):77-84. [Medline]. [emedicine.medscape.com] hypercalciuria and calcium-containing kidney stones, genetic screens of nephrolithiasis determinants have identified candidates involved in renal calcium handling, such as [emedicine.medscape.com] Growth Failure […] low-molecular-weight (LMW) proteinuria with hypercalciuria and nephrocalcinosis [1 - 4]. [asclepiusopen.com] INTRODUCTION Dent's disease refers to a group of X-linked renal tubular disorders including X-linked recessive nephrolithiasis, X-linked recessive hypophosphatemic rickets, and idiopathic [asclepiusopen.com] Staghorn Calculus Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med. 2002;346:77–84. 14. [aafp.org] (idiopathic, 50%), hypercalcemia (infants may have high Vitamin D levels, Iran J Kidney Dis 2012;6:186 ), hyperoxaluria (in vegetarians with oxalate rich diet), hyperuricosuria [pathologyoutlines.com] Idiopathic hypercalciuria Inherited trait Thiazide diuretic*, potassium citrate† Primary hyperparathyroidism Increased bone demineralization or increased intestinal calcium [aafp.org] Fibromyalgia However, the diagnosis is obvious before Chvostek's sign and/or tetanic EMG tracings without hypocalcaemia and/or hypercalciuria or a pattern of idiopathic PVM. [mgwater.com] However, diagnosis is obvious before Chvostek's sign and/or tetanic EMG tracings without hypocalcaemia and/or hypercalciuria or a pattern of idiopathic PVM. [mgwater.com] Pseudohypoaldosteronism of Infancy Calcium-handling disorders Relatively common disorders causing hypercalciuria and, less commonly, hypocalciuria: Idiopathic hypercalciuria [ 14 ] : High risk of calcium stone [patient.info] hypercalciuria Idiopathic membranous glomerulonephritis Idiopathic nephrotic syndrome Idiopathic steroid-sensitive nephrotic syndrome Idiopathic steroid-sensitive nephrotic [se-atlas.de] […] nephropathy type 1 Familial primary hypomagnesemia Familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis Familial primary hypomagnesemia with hypercalciuria [se-atlas.de] Chronic Fatigue Syndrome However, the diagnosis is obvious before Chvostek's sign and/or tetanic EMG tracings without hypocalcaemia and/or hypercalciuria or a pattern of idiopathic PVM. [mgwater.com] However, diagnosis is obvious before Chvostek's sign and/or tetanic EMG tracings without hypocalcaemia and/or hypercalciuria or a pattern of idiopathic PVM. [mgwater.com] Streptococcus Pneumoniae Ali and Rifat (8) studied 204 children with urinary lithiasis in Iraq, and identified the etiology in 189 (92.6%), and the others were considered idiopathic. [scielo.br] […] related to congenial malformations of the urinary tract associated with infection and also metabolic diseases such as cystinuria, renal tubular acidosis and alterations like hypercalciuria [scielo.br] Diuretic Toxicity Use: HTN, CHF, nephrogenicDI, idiopathic hypercalciuria. [quizlet.com] Hypercalciuria Thiazides inhibit calcium excretion, so they can be particularly effective in cases of idiopathic hypercalciuria. [lecturio.com] Low Chloride Risk factors for nephrolithiasis in patients with familial idiopathic hypercalciuria. Am J Med. 2002;113(2):99-103. (PubMed) 90. [lpi.oregonstate.edu] Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med. 2002;346(2):77-84. (PubMed) 25. [lpi.oregonstate.edu] Comparison of two diets for the prevention of recurrent stones in idiopathic hypercalciuria. N Engl J Med. 2002;346(2):77-84. (PubMed) 93. [lpi.oregonstate.edu] Enterolith Peripheral blood monocyte vitamin D receptor levels are elevated in patients with idiopathic hypercalciuria. J Clin Endocrinol Metab 2004;89: 4937-43. 29. [jsms.sch.ac.kr] Effects of low-calcium diet on urine calcium excretion, parathyroid function and serum 1,25(OH)2D3 levels in patients with idiopathic hypercalciuria and in normal subjects [jsms.sch.ac.kr] Drug-induced Hypokalemia hypercalciuria with nephrocalcinosis) Dysproteinemic syndromes (hypergammaglobulinemia, amyloidosis, cryoglobulinemia) Renal diseases (eg, renal transplant rejection, medullary [mja.com.au] […] and toxins (amphotericin B, lithium, toluene, amiloride, trimethoprim, pentamidine, vanadium) Calcium disorders (eg, primary hyperparathyroidism, vitamin D intoxication, idiopathic [mja.com.au] Laxative Abuse hypercalciuria. [ncbi.nlm.nih.gov] However, patients with underlying idiopathic hypercalciuria who develop eating disorders may be at increased risk of stone formation in the setting of low urine volume and [ncbi.nlm.nih.gov] We present an additional case of nephrolithiasis associated with laxative abuse, including detailed results of the patient's urine metabolic profiles, in a patient with idiopathic [ncbi.nlm.nih.gov]
