IgA Decreased Causes & Reasons

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IgA Decreased Symptom Checker: Possible causes include Celiac Disease. Check the full list of possible causes and conditions now! Talk to our Chatbot to narrow down your search.

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Possible Causes

Celiac Disease

Serum IgA tTG levels typically decrease as patients maintain a gluten-free diet. [ncbi.nlm.nih.gov]

During follow up with free diet the patient remained asymptomatic and all antibody titers decreased up to normalization. [ncbi.nlm.nih.gov]

[…] in IgA competent coeliac patients usually decreases on a gluten free diet. 36 One prominent regulator of the IgA class switch is transforming growth factor β (TGF-β), and [doi.org]

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IgA Glomerulonephritis

After supplement, urinary protein transiently increased, serum IgA circulating immune complexes decreased, and serum triglyceride and in-vitro platelet aggregation tended [ncbi.nlm.nih.gov]

Decreased OKT11 cells (37.83 /- 13.34, p less than 0.01) without any changes of OKT4 cells, but increased OKT8 cells (25.89 /- 6.70, p less than 0.01) in patients with IgA [ncbi.nlm.nih.gov]

The number of helper T-lymphocytes was found significantly increased particularly in the active phase of IgA glomerulonephritis, while that of suppressor lymphocytes decreased [ncbi.nlm.nih.gov]

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Common Variable Immunodeficiency

[…] lymphocytes or plasma cells that are capable of producing antibodies frequent bacterial infections Serology The following serological abnormalities may be present: serum IgA [radiopaedia.org]

In some patients, there is a decrease in both IgG and IgA in the blood; in other patients, levels of all three major immunoglobulin types, IgG, IgA and IgM, may be decreased [piduk.org]

(ii) decreased IgG, 105/502 cases (21%); (iii) decreased IgA, 131/502 cases (26%). [library.ehaweb.org]

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Selective IgA Immunodeficiency

A 20-year health follow-up study of 159 initially healthy blood donors with a severe deficiency of serum IgA ( 0.05 x 10(-3) g/L) and of 45 donors with decreased serum IgA [ncbi.nlm.nih.gov]

Abstract A 20-year health follow-up study of 159 initially healthy blood donors with a severe deficiency of serum IgA ( 3 g/L) and of 45 donors with decreased serum IgA (0.05 [doi.org]

What is IgA deficiency? Selective IgA Deficiency is decreased or absent IgA immunoglobulins in the blood serum and secretions. [patientslikeme.com]

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Upper Respiratory Infection

Baker’s yeast www glucan supplementation increases salivary IgA and decreases cold/flu symptomatic days after intense exercise. J.Diet.Suppl 10 (3):171-183, 2013. D. C. [fammed.wisc.edu]

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Cold Exposure

Modest whole-body cooling decreased circulating lymphocyte counts (25%; P 0.01), S-IgA concentration (36%; P 0.01) and secretion rate (24%; P 0.05). [ncbi.nlm.nih.gov]

However, modest whole-body cooling (T(re) 35.9 degrees C) decreased circulating lymphocytes, neutrophil degranulation and S-IgA, but responses were not amplified by prior [ncbi.nlm.nih.gov]

CAT duration was not different between trials [mean (SD): 133 (53) min] and T (re) decreased to 35.9 (0.3) degrees C. [ncbi.nlm.nih.gov]

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Tonsillitis

Notably, this response was associated with an important decrease in the incidence of tonsillitis and bacterial colonization of the oropharyngeal mucosa. [ncbi.nlm.nih.gov]

Immunization with heat-inactivated S. aureus elicited a significant antibody response characterized by production of IgG1 and IgG2 antibodies and, to a lesser extent, of IgA [ncbi.nlm.nih.gov]

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Malnutrition

[…] secretory immunoglobulin A (IgA) are some changes that may occur. [emedicine.com]

Loss of delayed hypersensitivity, fewer T lymphocytes, impaired lymphocyte response, impaired phagocytosis secondary to decreased complement and certain cytokines, and decreased [emedicine.com]

These immune changes predispose children to severe and chronic infections, most commonly, infectious diarrhea, which further compromises nutrition causing anorexia, decreased [emedicine.com]

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Hypoglycemia

Evaluation unexpectedly revealed hypogammaglobulinemia [decreased immunoglobulin G (IgG), IgM, and IgA]. [ncbi.nlm.nih.gov]

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Acne Vulgaris

Significant protoporphyrin IX (PpIX) fluorescence decrease was observed only for the group of red light (p 0.05). [aetna.com]

Lower pain intensity numeric rating scale (NRS) values and Investigator's Global Severity Assessment (IGA) grading for erythema of the IPL side were observed (p 0.05). [aetna.com]

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Metabolic Syndrome

May have deposition of IgA and C3 locally. Sometimes responds to local corticosteroids. [ncbi.nlm.nih.gov]

Pressure-induced localized lipodystrophy Trauma and decreased perfusion caused by repeated pressure to the same area over a long period of time. [ncbi.nlm.nih.gov]

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Food Allergy

Antigen-specific secretory IgA antibodies in the gut are decreased in a mouse model of food allergy. J Allergy Clin Immunol 114 : 377–382, 2004. [oadoi.org]

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Atopic Dermatitis

All patients had a decrease in IGA of at least 2 points using biweekly 300 or 150 milligram (mg) doses for an average treatment duration of 8.5 months (range: 6-11). [ncbi.nlm.nih.gov]

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Chronic Alcoholism

[…] naïve B cells, together with an increase in Ig-switched memory B lymphocytes and plasmablasts, particularly of IgA( ) cells. [ncbi.nlm.nih.gov]

CONCLUSIONS: AH and AWLD patients display a significantly reduced PB B-cell count, at the expense of decreased numbers of recently produced immature/regulatory B cells and [ncbi.nlm.nih.gov]

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Benign Prostatic Hyperplasia

Mean IgA was 0.039 g/l (range 0-0.38 g/l) and IgM – 0.189 g/l (range 0.021-3.51 g/l). [termedia.pl]

The total number of B cells was decreased and varied between 0-391 cells/µl, with the mean value of 26 cells/µl and 0.65%. [termedia.pl]

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Moraxella Catarrhalis

In this study, we observed decreased mucosal IgG and IgA responses to all four Mcat proteins in sOP children at healthy visits, which is in concert with our prior observations [frontiersin.org]

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Salpingitis

Negative seroconversion or a significant decrease in IgG antibody titer was demonstrated in four women (12.1%) and in IgA antibody titer in six women (18.1%). [ncbi.nlm.nih.gov]

Positive seroconversion or a significant increase ( or 4-fold) in IgG antibody titer was demonstrated in eight women (24.2%) and in IgA antibody titer in six women (18.1%) [ncbi.nlm.nih.gov]

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Toxoplasmosis

The serologic screening of IgM, IgA, and IgG is important to determine current or past infections of the pregnant women [88, 93]. [intechopen.com]

In these cases, where the detection of IgM, IgA, and parasites was negative at birth, it would have taken several months to observe the absence of a decrease of the IgG titer [doi.org]

Determination of T. gondii infection is crucial during pregnancy to decrease congenital toxoplasmosis [91] and thus companies try to develop new commercial tests. [intechopen.com]

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Complement Factor I Deficiency

[…] in number and function of T cells -B cells are decreased ( IgM, IgE and IgA are decreased with IgG usually normal) -X-linked recessive -Therapy includes platelet transfusions [quizlet.com]

IgA deficiency in saliva Decreased antibody response to immunizations Decreased neutrophil chemotaxis Nutritional Deficiencies Malabsorption can lead to zinc deficiency Anatomic [pedemmorsels.com]

Serum IgG, IgA, and IgM concentrations were elevated. The percentage of T-lymphocytes was decreased, but T-cell response to mitogens was normal. [cdc.gov]

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Renal Function Impairment

Kidney biopsy showed diffuse mesangial proliferation and IgA deposit in mesangial region in 1 patient. [ncbi.nlm.nih.gov]

All of the 25 patients had cornea K-F ring and the level of ceruloplasmin decreased. Six patients had a family history of HLD. [ncbi.nlm.nih.gov]

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Acute Otitis Media

NP mucosal IgG and IgA were quantified by ELISA. [ncbi.nlm.nih.gov]

RESULTS: Higher NP mucosal antibody levels to S. pneumoniae proteins correlated with significantly decreased likelihood of developing AOM caused by S. pneumoniae during 3 [ncbi.nlm.nih.gov]

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Cholestatic Jaundice

Forteen days post-operation, the levels of immunoglobulin G (IgG), immunoglobulin A (IgA) and immunoglobulin M (IgM) in the group undergoing palliative surgery decreased significantly [ncbi.nlm.nih.gov]

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Proteus

As the incidence of pediatric IgA nephropathy patients who show hypertension or decreased renal function at onset is relatively rare in comparison with adults, proteinuria [journals.plos.org]

Risk factors for ESKD in childhood IgA nephropathy have also been reported [ 9 – 11 ]. [journals.plos.org]

[…] with IgA nephropathy in Japan, 11% have been reported to reach ESKD within 15 years [ 8 ], although there have been few reports regarding long-term prognosis of childhood IgA [journals.plos.org]

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Chronic Kidney Insufficiency

IgA Nephropathy Shortens Life Expectancy In a study, IgA nephropathy patients lived a median 6 fewer years than age-matched controls without the disease. [renalandurologynews.com]

Canagliflozin Lowers ESRD Risk in Diabetic Kidney Disease In a study of patients with type 2 diabetes and chronic kidney disease, canagliflozin, an SGLT2 inhibitor, decreased [renalandurologynews.com]

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Acute Renal Failure

[…] is decreased[10]. [ncbi.nlm.nih.gov]

[…] becomes stagnant in the biliary system, the intraductal pressure increases, the tight junction between cholangiocytes widen, Kupffer cells malfunction and the production of IgA [ncbi.nlm.nih.gov]

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Psoriasis

On a scale from 0 none to 5 very severe scalp psoriasis, the clobetasol propionate group achieved a reduction from 3.4 to 1.9 (‐44%) whereas the tar blend group decreased [doi.org]

According to Monk 1995, which included 34 participants, the IGA of participants treated with "ung cocois co" improved by 73% compared with 42% improvement in participants [doi.org]

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Vasovagal Syncope

Nagu iga süstimise järgselt, võib harvadel juhtudel pärast Twinrix Junior i manustamist noorukitele tekkida vasovagaalne sünkoop. [mymemory.translated.net]

English discomfort at injection including decreased blood pressure and heart rate (vasovagal reaction) malaise Last Update: 2017-04-26 Usage Frequency: 1 Quality: Estonian [mymemory.translated.net]

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Keratitis

• Characteristics of an autoimmune process • decrease in number of suppressor T cells relative to no of helper T cells • elevated IgA levels • Higher circulating IgG antibodies [slideshare.net]

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Cholangitis

[…] is decreased[10]. [wjgnet.com]

Finally, increased biliary pressure decreases production of IgA immunoglobulins in the bile.[11] This results in bacteremia (bacteria in the blood stream) and gives rise to [en.wikipedia.org]

Finally, increased biliary pressure decreases production of IgA immunoglobulins in the bile. [11] This results in bacteremia (bacteria in the blood stream) and gives rise [en.wikipedia.org]

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Polyarthritis

With this treatment acute exacerbations of her chronic lung disease decreased in frequency. [ijponline.biomedcentral.com]

Table 1 Immunologic investigations in our patent IgA (g/l) 0.08 0.07 0.11-2.51 IgM 0.04 0.06 0.13-2.51 IgG 0.70 10.8 b 6.54-15.94 IgE (IU/ml) 50 - Absolute lymphocyte count [ijponline.biomedcentral.com]

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