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127 Possible Causes for Immunodeficiency Is Progressive, Severe Hypoxemia

  • Anemia

    […] from HIV infection to autoimmune immunodeficiency syndrome (AIDS), with a correlation between CD4 T-lymphocyte counts and Hb levels. 7,16 The causes of anemia in HIV/AIDS[ajmc.com] […] virus (HIV)–infected patients can have serious implications, which vary from functional and quality-of-life decrements to an association with disease progression and decreased[academic.oup.com] […] antiretroviral therapy (HAART). 7 Anemia still occurs at high rates when HIV therapy regimens include zidovudine (AZT). 7 The incidence of anemia increases with disease progression[ajmc.com]

  • Pneumonia

    She was emergently admitted to our hospital due to the worsening exertional dyspnea and severe hypoxemia.[ncbi.nlm.nih.gov] Common symptoms of PCP include progressive shortness of breath, nonproductive cough, and low‐grade fever.[doi.org] However, three months after treatment he presented with shortness of breath and severe hypoxemia associated with peripheral eosinophilia.[dx.doi.org]

  • Interstitial Lung Disease

    Sleep-disordered Breathing • For patients with sleep-disordered breathing complicated by severe nocturnal hypoxemia who cannot tolerate positive airway pressure therapy or[doi.org] A 61-year-old woman presented with longstanding cough and progressive dyspnoea.[ncbi.nlm.nih.gov] Interstitial Lung Disease • For patients with interstitial lung disease complicated by severe chronic hypoxemia, we recommend that home oxygen therapy be prescribed (strong[doi.org]

  • Hepatopulmonary Syndrome

       50 mm Hg (8/41 with very severe hypoxemia versus 3/49 without severe hypoxemia, P   0.053), and there was a significantly increased risk for patients with anatomic shunting[ncbi.nlm.nih.gov] Clinical progression of hepatitis C virus-related chronic liver disease in human immunodeficiency virus-infected patients undergoing highly active antiretroviral therapy.[siicsalud.com] Liver transplantation is the only known cure for HPS, but patients can develop severe posttransplant hypoxemia, defined as a need for 100% inspired oxygen to maintain a saturation[ncbi.nlm.nih.gov]

  • Acute Bronchitis

    When the FEV1 falls below about 0.8 L, patients are at risk of hypoxemia, hypercapnia, and cor pulmonale.[msdmanuals.com] These patients need careful periodic monitoring to minimize further lung damage and progression to chronic irreversible lung disease.[emedicine.medscape.com] Patients with anemia (for reasons other than COPD) have disproportionately severe dyspnea. The differential WBC count may be helpful.[msdmanuals.com]

  • Thrombocytopenia

    We made this judgment on the basis of normal MPVs and good responses to platelet transfusions. (2) The low platelet counts are associated with intrauterine hypoxemia (elevated[pediatrics.aappublications.org] Patients with Chédiak-Higashi syndrome have severe immunodeficiency due to abnormal lymphocyte lytic granules and progressive neurologic degeneration.[merck.com] […] that creates fetal growth restriction, not the pathology that produces preeclampsia without fetal growth restriction. (3) The thrombocytopenia is typically only moderately severe[pediatrics.aappublications.org]

  • Heart Failure

    It is important to close a patent foramen before LVAD support because significant right-to-left shunting may occur postoperatively, leading to severe hypoxemia under certain[doi.org] […] virus (HIV)–associated cardiomyopathy generally progresses to death within 100 days of diagnosis in patients who are not treated with antiretroviral drugs.[emedicine.com] […] dyspnea may occur as a consequence of the reduced cardiac output, poor perfusion of respiratory muscles, hypoxemia, and metabolic acidosis.[emedicine.medscape.com]

  • Congestive Heart Failure

    It is important to close a patent foramen before LVAD support because significant right-to-left shunting may occur postoperatively, leading to severe hypoxemia under certain[doi.org] […] virus (HIV)–associated cardiomyopathy generally progresses to death within 100 days of diagnosis in patients who are not treated with antiretroviral drugs.[emedicine.com] Oxygen therapy should be administered to relieve symptoms related to hypoxemia. (Level of Evidence: C) New recommendation 6.[doi.org]

  • Liver Cirrhosis

    hypoxemia are excluded.[dx.doi.org] Combined sequential LT and HSCT resolved the cirrhotic evolution and corrected the immunodeficiency so that the infection responsible for the progressive sclerosing cholangitis[ncbi.nlm.nih.gov] In rare cases, rapidly progressive fibrosis may be observed in patients with HCV infection after liver transplantation or in patients with human immunodeficiency virus–HCV[pubs.rsna.org]

  • Pulmonary Alveolar Proteinosis

    It may be difficult to perform WLL in patients with severe hypoxemia wherein patients do not tolerate single lung ventilation.[ncbi.nlm.nih.gov] PAP is characterized morphologically by the inappropriate and progressive 'occupation' of the alveolar spaces by an excessive amount of unprocessed surfactant, limiting gas[ncbi.nlm.nih.gov] Rarely, hyperbaric chamber or extracorporeal membrane oxygenation (ECMO) has been utilized to perform WLL to manage severe hypoxemia, with venovenous ECMO being used more[ncbi.nlm.nih.gov]

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