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1,682 Possible Causes for Immunoglobulin A Decreased, Myoclonic Jerking, Onset of Disease between 25 and 40 Years of Age

  • Wilson Disease

    jerking similar to that seen in progressive myoclonic syndrome.[web.archive.org] Onset is slow and begins between 11 and 25 years of age. Signs and Symptoms In about 40 to 50% of patients, the disease first affects the central nervous system (CNS).[diagnose-me.com] Autonomic disturbances including postural hypotension, abnormal sweating, and sphincter and sexual dysfunction are frequently present. 33 Very rarely, teenage patients exhibit myoclonic[web.archive.org]

  • Hypoglycemia

    Evaluation unexpectedly revealed hypogammaglobulinemia [decreased immunoglobulin G (IgG), IgM, and IgA].[ncbi.nlm.nih.gov] In newborns, hypoglycemia can produce irritability, jitters, myoclonic jerks, cyanosis, respiratory distress, apneic episodes, sweating, hypothermia, somnolence, hypotonia[en.wikipedia.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Alzheimer Disease

    The R47H substitution encoded by rs75932628-T is located within the extracellular immunoglobulin-like domain of TREM2.[doi.org] After 36 hours of donepezil remission, the frequency of the myoclonic jerks was sharply reduced. The patient remains asymptomatic after 6 months of follow-up.[ncbi.nlm.nih.gov] The amino acid substitution may result in decreased affinity of TREM2 for its natural ligands and affect its signaling.[doi.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Opsoclonus-Myoclonus Syndrome

    Later symptoms included body jerks, drooling, refusal to walk or sit, speech problems, decreased muscle tone, opsoclonus, and inability to sleep.[ncbi.nlm.nih.gov] Clinical features of OMS include opsoclonus with myoclonic jerks and cerebellar ataxia.[ncbi.nlm.nih.gov] jerks.[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Benign Adult Familial Myoclonic Epilepsy

    By the jerk-locked averaging method, a positive spike time-locked to the myoclonic jerk was demonstrated in four patients before 15-20 msec of myoclonic jerk.[ci.nii.ac.jp] Celiac disease (or gluten sensitive enteropathy): The age of onset may vary between 40 - 80 years and the mean duration of ataxia between 3 to 25 years.[neuroweb.us] ., adj myoclon ic. A single myoclonic arm or leg jerk is normal when the person is falling asleep. Myoclonic jerks are severe with grand mal seizures.[medical-dictionary.thefreedictionary.com]

    Missing: Immunoglobulin A Decreased
  • Amyotrophic Lateral Sclerosis

    The titer of anti-LRP4 antibody subsequently decreased. However, the therapeutic effect was transient, and ALS symptoms progressed.[ncbi.nlm.nih.gov] Ultimately, the AZPs cluster and decrease in number.[web.archive.org] A series of immunotherapies, including steroid pulse therapy, intravenous immunoglobulin, and plasmapheresis, was performed, and the myasthenic symptoms partially improved[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Mucolipidosis

    Low serum levels of immunoglobulin A, G2, and G4 were also observed before HSCT; however, these values normalized after transplantation.[ncbi.nlm.nih.gov] Random multifocal myoclonic jerks had diffuse EEG correlates [Figure 1]. Attenuation of visual evoked potentials was noted.[neurologyindia.com] Although comparing before and after cord blood transplantation results, we observed that lysosomal enzyme activities in the plasma decreased by approximately 20-40%.[ncbi.nlm.nih.gov]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Lennox-Gastaut Syndrome

    Of these patients 6 improved following such treatment with a decrease in fits and an improvement in the EEG.[doi.org] In such cases, massive myoclonic jerks, myoclonic-atonic attacks, as well as atonic seizures may occur, though much less frequent and severe than the other manifestations.[epilepsyontario.org] Lennox and Davis first correlated the slow spike-and-wave EEG pattern with a distinctive group of clinical manifestations including specific seizure types (myoclonic jerks[medlink.com]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Aicardi's Syndrome

    Hepatology (1996) [ Pubmed ] Amb a 1-immunostimulatory oligodeoxynucleotide conjugate immunotherapy decreases the nasal inflammatory response.[wikigenes.org] Asymmetric myoclonic jerks developed at one month of age.[ncbi.nlm.nih.gov] Med. (1977) [ Pubmed ] Incidence of rejection and infection after liver transplantation as a function of the primary disease: possible influence of alcohol and polyclonal immunoglobulins[wikigenes.org]

    Missing: Onset of Disease between 25 and 40 Years of Age
  • Herpes Simplex Encephalitis

    Treatment consists of steroids, intravenous immunoglobulin, and plasma exchange.[neuropathology-web.org] This leads to decrease of the NMDAR in GABAergic and glutamatergic synapses and increase of extracellular glutamate which causes the symptoms.[neuropathology-web.org]

    Missing: Onset of Disease between 25 and 40 Years of Age

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