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21 Possible Causes for Immunoglobulin G Increased, Increased Bone Marrow Megakaryocytes

  • Immune Thrombocytopenic Purpura

    Thus, the patients were diagnosed as immune thrombocytopenic purpura due to the isolated thrombocytopenia, large platelets on blood and bone marrow smears and increased megakaryocytes[ncbi.nlm.nih.gov] Elevated serum immunoglobulin G (IgG) was detected, and tests for platelet-associated IgG and anti-nuclear antibody were positive.[ncbi.nlm.nih.gov] Thrombocytopenia was refractory to platelet infusions and bone marrow aspiration revealed remission status for ALL along with increased megakaryocytes.[ncbi.nlm.nih.gov]

  • Sjogren's Syndrome

    A bone marrow examination revealed increased megakaryocytes with reticulin fibrosis, and the histopathology of an axillary lymph node was consistent with mixed-type Castleman[ncbi.nlm.nih.gov] There is also evidence for increased intrathecal immunoglobulin G (IgG) synthesis.[epilepsy.com]

  • Myeloproliferative Disease

    ET could be diagnosed by the presence of large platelet in peripheral blood smear, an increase in clustered large megakaryocytes in bone marrow smear and the presence of the[ncbi.nlm.nih.gov] It is characterized by sustained thrombocytosis in the blood and increased numbers of large, mature megakaryocytes in the bone marrow.[quizlet.com] megakaryocyte polyploidization; and increased reticulin fibrosis of the bone marrow and spleen.[ncbi.nlm.nih.gov]

  • Polycythemia Vera

    When done, bone marrow examination typically shows panmyelosis, large and clumped megakaryocytes, and sometimes an increase in reticulin fibers.[merck.com] Cytology The bone marrow is hypercellular with normal morphology. Clusterd mature megakaryocytes may be seen. The iron stores are absent.[atlasgeneticsoncology.org] Bone marrow biopsy showing hypercellularity for age with trilineage growth (panmyelosis) including prominent erythroid, granulocytic and megakaryocytic proliferation with[pathologyoutlines.com]

  • Wilson Disease

    The platelet count was found to be low with lack of increased number of megakaryocytes in the bone marrow aspiration suggesting the thrombocytopenia was not exclusively owing[ncbi.nlm.nih.gov]

  • Thrombocytopenia

    Normal or increased megakaryocytes on bone marrow aspirate/bx.[clinicaltrials.gov] The dose of intravenous methylprednisone was increased to 80 g every 8 hours, and intravenous immunoglobulin (IVIG) treatment was started at 40 g/d for 5 days.[academic.oup.com] Other causes of thrombocytopenia include a congenital lack of megakaryocytes (cells in the bone marrow that give rise to platelets) and increased platelet destruction (e.g[britannica.com]

  • Hereditary Spherocytosis

    Bone marrow examination revealed normal cellularity with increasing of megakaryocytes (305/μl).[jhoonline.biomedcentral.com] The results of anti-HPV immunoglobulin M (IgM) and immunoglobulin G (IgG) measured at admission were both positive, and HPV-B19 deoxyribonucleic acid (DNA) increased to 10[bmcresnotes.biomedcentral.com] Increment of abnormal blasts, hemophagocytes and dysplastic cells were not found on bone marrow film.[jhoonline.biomedcentral.com]

  • Autoimmune Thrombocytopenia

    Normal or increased megakaryocytes on bone marrow aspirate/bx.[clinicaltrials.gov] In most cases, treatment with high-dose (1-2 g/kg body weight) intravenous immunoglobulin has been demonstrated to result in an increase in platelet counts after one day of[ncbi.nlm.nih.gov] In patients with ITP, bone marrow examination reveals normal or possibly increased numbers of megakaryocytes in an otherwise normal bone marrow sample.[merckmanuals.com]

  • Evan's Syndrome

    Platelet count was 2.0 10 4 /μ l , and serum LDH was increased (798U/ l ). Increased megakaryocytes and erythroid hyperplasia were identified in the bone marrow.[jstage.jst.go.jp] Intravenous Immunoglobulin G was given in a dose of 400 mg/kg/d on day 21st for four days. Platelet count increased and after two days.[jpma.org.pk] Bone marrow aspirate examination showed normoblastic erythroid hyperplasia with increased number of megakaryocytes and its many immature forms.[amhsjournal.org]

  • Adult Idiopathic Neutropenia

    bone marrow and absence of splenomegaly.[elsevier.es] ) to temporarily increase neutrophil counts.[en.wikipedia.org] Idiopathic thrombocytopenic purpura is an autoimmune disease characterized by the presence of isolated thrombopenia with a normal or increased number of megakaryocytes in[elsevier.es]

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