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1,765 Possible Causes for Immunoglobulin G Increased, Intrahepatic Cholestasis, Virus Associated Hemophagocytic Syndrome

  • Sickle Cell Disease

    cholestasis, and a non-SCD cause of hepatopathy in a patient with viral hepatitis.[ncbi.nlm.nih.gov] Sickle RBCs have increased immunoglobulin G (IgG) on the cell surface.[emedicine.com] Few data have been provided on chronic sickle cell intrahepatic cholestasis (SCIC) clinical course, although cirrhosis has been reported in sickle cell disease.[ncbi.nlm.nih.gov]

  • Chronic Active Hepatitis B

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Compression of bile canaliculi may result in intrahepatic cholestasis.[hepatitisbannual.org] Laboratory testing should show evidence of abnormal liver chemistry tests, increased total immunoglobulin G (IgG) or gamma-globulin levels and autoantibodies.[clinicaladvisor.com]

  • Chronic Active Hepatitis

    Bone marrow biopsy showed hypocellularity, histiocytic hyperplasia, and hemophagocytosis consistent with a virus-associated hemophagocytic syndrome (VAHS).[ncbi.nlm.nih.gov] Laboratory testing should show evidence of abnormal liver chemistry tests, increased total immunoglobulin G (IgG) or gamma-globulin levels and autoantibodies.[clinicaladvisor.com] Frequently, immune serum markers are present; they include autoantibodies against liver-specific and non–liver-specific antigens and increased immunoglobulin G (IgG) levels[emedicine.medscape.com]

  • Hodgkin Lymphoma

    Hodgkin lymphoma-associated hemophagocytic syndrome: a disorder strongly correlated with Epstein-Barr virus. Clin Infect Dis. 2008 Aug 15. 47(4):531-4. [Medline].[emedicine.medscape.com]

  • Non-Hodgkin Lymphoma

    There are many different types of non-Hodgkin lymphoma (NHL). Doctors also give NHL a grade, depending on how quickly it is likely to grow. Low grade NHL Find out about low grade non-Hodgkin lymphoma (NHL), what low grade means, and different types. High grade NHL Find out about high grade lymphomas, what high[…][cancerresearchuk.org]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Primary Biliary Cirrhosis

    Abstract Primary biliary cirrhosis (PBC) is characterized by progressive nonsuppurative destruction of small bile ducts, resulting in intrahepatic cholestasis, fibrosis and[ncbi.nlm.nih.gov] Further lab tests ( Table I ) showed increased levels and titers of antinuclear antibodies (ANA) speckled pattern and anti-smooth muscle antibodies (immunoglobulin G [IgG][consultant360.com] In June 2008, she was admitted with intrahepatic cholestasis, steatorrhea, and spontaneous fractures of various ribs.[ncbi.nlm.nih.gov]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Viral Hepatitis

    Oral S-adenosylmethionine in the symptomatic treatment of intrahepatic cholestasis. A double-blind, placebo-controlled study. Gastroenterology 1990;99:211 - 215.[cancercarewny.com]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Sarcoidosis

    Hepatosplenomegaly, intrahepatic cholestasis, and portal hypertension are rare. w7 Renal (5%) —Extrarenal production of calcitriol by macrophages can result in renal calculi[doi.org] Chronic intrahepatic cholestasis, hepatic dysfunction, cirrhosis and portal hypertension are all severe but rare complications of sarcoidosis.[dx.doi.org] Liver involvement while granulomas are found in up to 60–80% of liver biopsy specimens, abnormalities of biological tests, primarily cholestasis, are evidenced in only about[dx.doi.org]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Systemic Amyloidosis

    It is most commonly due to intrahepatic cholestasis 26 although obstruction of the bile ducts by amyloid deposits has also been reported. 27 Only four of our patients with[gut.bmj.com] In Figure 2 A, generally stable, low ( 1.5 g/dL) monoclonal immunoglobulin (M-Ig) levels are present for years before diagnosis, with a gradual increase resulting in a subsequent[doi.org] Liver function tests typically suggest intrahepatic cholestasis with elevation of alkaline phosphatase and later bilirubin, although jaundice is rare.[merckmanuals.com]

    Missing: Virus Associated Hemophagocytic Syndrome
  • Amyloidosis

    We report here a case of portal hypertension, ascites, and severe intrahepatic cholestasis as the initial presentation of hepatic amyloidosis and multiple myeloma, which followed[ncbi.nlm.nih.gov] Liver function tests typically suggest intrahepatic cholestasis with elevation of alkaline phosphatase and later bilirubin, although jaundice is rare.[msdmanuals.com]

    Missing: Virus Associated Hemophagocytic Syndrome

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