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29 Possible Causes for Immunoglobulin M Decreased, Increased Susceptibility to Infections, Recurrent Otitis Media

  • Common Variable Immunodeficiency

    susceptibility to infections.[] […] serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic of the disorder, about 50% of CVID patients also have decreased immunoglobulin M (IgM[] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[] Serum immunoglobulin determination at Walter Reed General Hospital revealed an immunoglobulin G level of 150 mg per 100 ml and absence of immunoglobulins A and M.[] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[] This disorder affects children and results in increased susceptibility to infections. One possible treatment is a bone marrow transplant.[]

  • Nephrotic Syndrome

    […] plt aggregation), low complement, hyperlipidemia (increased hepatic synthesis of lipoprotein), increased susceptibility to infections (loss of IgG).[] The side effects of these drugs include increased susceptibility to infection, hair loss and decreased blood cell production.[] susceptibility to new infection or reactivation of latent infections Suppression of the hypothalamic-pituitary-axis (HPA) may occur following prolonged therapy with the potential[]

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[] Although decreased serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic, approximately 50% of patients with the deficiency also have diminished[] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by thrombocytopenia, small platelets, eczema, increased susceptibility to infection, and immunodeficiency[] otitis media infections.[] However, with respect to the major symptoms of WAS, none of these three patients showed either thrombocytopenia or increased susceptibility to infection, but one patient showed[]

  • Congenital Agammaglobulinemia

    susceptibility to infection beyond that seen in nonlymphopenic agammaglobu-linemia.[] media Otitis media Otitis media Otitis media Sinusitis - - Pneumonia Bronchiectasis - - Arthritis - - Skin infection - - Septicemia Meningitis/encephalitis - - Recurrent[] susceptibility to infection of skin and respiratory tract Mild bleeding diathesis Partial oculocutaneous albinism Progressive peripheral neuropathy Lymphoma-like syndrome[]

  • Ataxia Telangiectasia

    […] to infections.[] Ataxia-telangiectasia is a hereditary disorder characterized by incoordination, dilated capillaries, and an immunodeficiency that causes increased susceptibility to infections[] […] to infection.[]

  • Adenosine Deaminase Deficiency

    This, in turn, causes a decreased number of lymphocytes and a drastically increased susceptibility to infection (severe combined immunodeficiency, SCID).[] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[] The classic symptoms of SCID include an increased susceptibility to a variety of infections, including ear infections (acute otitis media), pneumonia or bronchitis, oral thrush[]

  • Agammaglobulinemia

    Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion.[] Norlin AC, Sairafi D, Mattsson J, Ljungman P, Ringden O, Remberger M. Allogeneic stem cell transplantation: low immunoglobulin levels associated with decreased survival.[] ., in addition to giardiasis) are typical for agammaglobulinemia patients, and recurrent otitis media is described in the vast majority of cases.[]

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