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29 Possible Causes for Immunoglobulin M Decreased, Increased Susceptibility to Infections, Recurrent Otitis Media

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] […] serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic of the disorder, about 50% of CVID patients also have decreased immunoglobulin M (IgM[medigoo.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Serum immunoglobulin determination at Walter Reed General Hospital revealed an immunoglobulin G level of 150 mg per 100 ml and absence of immunoglobulins A and M.[pubs.rsna.org] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[ncbi.nlm.nih.gov] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[medbullets.com] This disorder affects children and results in increased susceptibility to infections. One possible treatment is a bone marrow transplant.[study.com]

  • Nephrotic Syndrome

    […] plt aggregation), low complement, hyperlipidemia (increased hepatic synthesis of lipoprotein), increased susceptibility to infections (loss of IgG).[errolozdalga.com] The side effects of these drugs include increased susceptibility to infection, hair loss and decreased blood cell production.[kidney.org] susceptibility to new infection or reactivation of latent infections Suppression of the hypothalamic-pituitary-axis (HPA) may occur following prolonged therapy with the potential[actharnephrology.com]

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] Although decreased serum levels of immunoglobulin G (IgG) and immunoglobulin A (IgA) are characteristic, approximately 50% of patients with the deficiency also have diminished[emedicine.medscape.com] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by thrombocytopenia, small platelets, eczema, increased susceptibility to infection, and immunodeficiency[ncbi.nlm.nih.gov] otitis media infections.[emedicine.medscape.com] However, with respect to the major symptoms of WAS, none of these three patients showed either thrombocytopenia or increased susceptibility to infection, but one patient showed[ncbi.nlm.nih.gov]

  • Congenital Agammaglobulinemia

    susceptibility to infection beyond that seen in nonlymphopenic agammaglobu-linemia.[pediatrics.aappublications.org] media Otitis media Otitis media Otitis media Sinusitis - - Pneumonia Bronchiectasis - - Arthritis - - Skin infection - - Septicemia Meningitis/encephalitis - - Recurrent[bmcpediatr.biomedcentral.com] susceptibility to infection of skin and respiratory tract Mild bleeding diathesis Partial oculocutaneous albinism Progressive peripheral neuropathy Lymphoma-like syndrome[quizlet.com]

  • Ataxia Telangiectasia

    […] to infections.[ncbi.nlm.nih.gov] Ataxia-telangiectasia is a hereditary disorder characterized by incoordination, dilated capillaries, and an immunodeficiency that causes increased susceptibility to infections[merckmanuals.com] […] to infection.[immunedisease.com]

  • Adenosine Deaminase Deficiency

    This, in turn, causes a decreased number of lymphocytes and a drastically increased susceptibility to infection (severe combined immunodeficiency, SCID).[britannica.com] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[medbullets.com] The classic symptoms of SCID include an increased susceptibility to a variety of infections, including ear infections (acute otitis media), pneumonia or bronchitis, oral thrush[genome.gov]

  • Agammaglobulinemia

    Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion.[ncbi.nlm.nih.gov] Norlin AC, Sairafi D, Mattsson J, Ljungman P, Ringden O, Remberger M. Allogeneic stem cell transplantation: low immunoglobulin levels associated with decreased survival.[doi.org] ., in addition to giardiasis) are typical for agammaglobulinemia patients, and recurrent otitis media is described in the vast majority of cases.[symptoma.com]

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