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1,255 Possible Causes for Immunoglobulin M Increased, Onset of Symptoms in the Fourth to Sixth Decade of Life, Xerostomia

  • Rheumatoid Arthritis

    The likelihood of persistent arthritis increases with the level of anti-citrullinated peptide antibody and immunoglobulin M rheumatoid factor: a longitudinal study of 376[doi.org] Sjogren’s syndrome is an autoimmune condition that affects exocrine gland function, leading to a reduction in tear production (keratoconjunctivitis sicca), oral dryness (xerostomia[hopkinsarthritis.org] Sjögren’s syndrome used in this and other studies, 36, 37 the frequency of the diagnosis depends heavily on the availability of specific tests for the evaluation of possible xerostomia[doi.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Sjögren Syndrome

    Sjogren's syndrome, involving sicca symptoms with xerostomia, stomatitis, and considerable pain is a difficult-to-treat autoimmune disease where the treatment options are[ncbi.nlm.nih.gov] Eye dryness and xerostomia were assessed by the Schirmer's test, the Fox test and the visual analogue scale (VAS).[ncbi.nlm.nih.gov] Xerostomia Other names Dry mouth,[1] dry mouth syndrome[2] Xerostomia, also known as dry mouth,[1] is dryness in the mouth, which may be associated with a change in the composition[en.wikipedia.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Primary Biliary Cirrhosis

    […] alkaline phosphatase levels results in an improvement of cholestasis as compared to placebo, with a parallel decrease of aminotransferases and immunoglobulin M, as well as[ncbi.nlm.nih.gov] She was 38 years old and was admitted to our hospital for generalized pruritus, xerostomia, xerophthalmia, fatigue, and reticulonodular changes on her chest X-ray.[ncbi.nlm.nih.gov] Pinto A: Management of xerostomia and other complications of Sjögren's syndrome. Oral Maxillofac Surg Clin North Am 2014;26:63-73.[karger.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Diffuse Scleroderma

    Muscle weakness Muscular weakness 0001324 Osteolysis Breakdown of bone 0002797 Pulmonary fibrosis 0002206 Skin ulcer Open skin sore 0200042 Telangiectasia of the skin 0100585 Xerostomia[rarediseases.info.nih.gov]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Cryoimmunoglobulinemic Syndrome

    A 68-year-old woman had been complained of xerostomia since she was 30 years old.[ci.nii.ac.jp] MC and pSS may share various symptoms: xerostomia and/or xerophthalmia, arthralgias, purpura, RF and serum cryoglobulins, and the possible complication with B-cell lymphoma[ojrd.biomedcentral.com] […] arthralgias, while clear clinical signs of arthritis (usually mild, non-erosive oligoarthritis) are relatively rare [ 11, 12, 25, 28 ] Almost half MC patients complain of xerostomia[ojrd.biomedcentral.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Idiopathic Cryoglobulinemia

    […] onoclonal G ammopathy of U nknown S ignificance Long term: Increased risk of myeloma in 10 to 20 years (1% - 2%/ year) Follow-up evaluation: Test quantitative immunoglobulins[neuromuscular.wustl.edu] Affected individuals may also develop an abnormally dry mouth (xerostomia) and abnormally dry eyes (xerophthalmia), a combination which is sometimes referred to as Sicca syndrome[rarediseases.org] MC and pSS may share various symptoms: xerostomia and/or xerophthalmia, arthralgias, purpura, RF and serum cryoglobulins, and the possible complication with B-cell lymphoma[ojrd.biomedcentral.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Multiple Myeloma

    In myeloma, plasma cells transform into cancerous cells and produce increased amounts of antibodies (immunoglobulins) called monoclonal proteins (M-spike), as well as incomplete[urmc.rochester.edu] […] common manifestations include, among others: jaw claudication [ 21 ], gastroparesis and intestinal pseudo-obstruction, polyarthralgia [ 22 ], muscle pseudohypertrophy [ 23 ], xerostomia[karger.com] […] protein 30g/L IgA SMM Immunoparesis with reduction of 2 uninvolved immunoglobulin isotypes Serum involved/uninvolved FLC ratio 8 (but Progressive increase in M protein level[ncbi.nlm.nih.gov]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Cryoglobulinemia

    Renal Glomerulonephritis – hematuria, proteinuria, casts Peripheral nerves Neuropathies Other Musculoskeletal – arthralgias Hepatic – hepatitis Otorhinolaryngological – xerostomia[arupconsult.com] Affected individuals may also develop an abnormally dry mouth (xerostomia) and abnormally dry eyes (xerophthalmia), a combination which is sometimes referred to as Sicca syndrome[rarediseases.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Sarcoidosis

    […] is the most frequent cause of sarcoidosis-related death Bone 5% Osteolytic or cystic lesions Osteopenia Oral 5% Asymptomatic parotid swelling (most common) Parotitis with xerostomia[merckmanuals.com]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life
  • Loeffler Endocarditis

    The patient A 44-year-old man with no past medical history presented with bilateral parotid gland enlargement and xerostomia.[acphospitalist.org]

    Missing: Onset of Symptoms in the Fourth to Sixth Decade of Life