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18 Possible Causes for Immunoglobulin M Increased, Tryptophan Increased

  • Acute Glomerulonephritis

    Ximena Berríos Edda Lagomarsino Eric Solar Gloria Sandoval Beatriz Guzmán Ingrid Riedel Original Article First Online: 20 December 2003 302 Downloads 40 Citations Abstract In order to characterize the epidemiological and clinical picture of post-streptococcal acute glomerulonephritis (PSAGN), a prospective study was[…][doi.org]

  • Post-Streptococcal Glomerulonephritis

    A 7 years old male with severe bilateral vesicoureteral reflux developed acute renal failure without evidence of either infection or obstruction. The diagnosis of acute post-streptococcal glomerulonephritis was confirmed by clinical, serological and histological evaluation. The patient's creatinine clearance decreased[…][ncbi.nlm.nih.gov]

  • Toxoplasmosis

    At least some of these effects, possibly mediated by increased dopamine and decreased tryptophan, are products of manipulation activity by Toxoplasma aiming to increase the[ncbi.nlm.nih.gov] tryptophan levels in all brain regions ( Dunn, 2006 ) or alternatively there are only proximate effects on serotonin in the specific area surrounding the cysts.[doi.org] Irritability rather than depression during interferon treatment is linked to increased tryptophan catabolism.[ncbi.nlm.nih.gov]

  • Visceral Leishmaniasis

    Increased frequency of malaria attacks in subjects co-infected by intestinal worms and Plasmodium falciparum malaria. Trans. R. Soc. Trop. Med.[doi.org] Immunity and tolerance to Aspergillus involve functionally distinct regulatory T cells and tryptophan catabolism. J. Immunol. 176, 1712–1723 (2006). 72.[doi.org]

  • Hookworm Infection

    Increasing concentrations of hematin were added and incubated for 3 min prior to measurement. Animal vaccine trials.[iai.asm.org] Changes in fluorescence were recorded with a Shimadzu spectrofluorometer (RF-5301 PC) with excitation and emission wavelengths for intrinsic protein fluorescence (tryptophan[iai.asm.org]

  • African Trypanosomiasis

    Results: Kynurenine concentration in CSF was increased in both the early and late stages of disease, with a progressive increase in tryptophan oxidation associated with stage[ncbi.nlm.nih.gov] Methods: We measured cerebrospinal fluid (CSF) tryptophan and kynurenine metabolite concentrations in patients infected with Trypanosoma brucei rhodesiense, using liquid chromatography-mass[ncbi.nlm.nih.gov] Kynurenine pathway activation was associated with increases in neuroinflammatory markers, but there was no clear relationship to neurological symptoms.[ncbi.nlm.nih.gov]

  • Dysthymic Disorder

    Likewise, researchers found that huge increases in brain serotonin, arrived at by administering high-dose L-tryptophan, were ineffective at relieving depression [ 10 ].[ncbi.nlm.nih.gov] […] plasma concentrations of complement proteins, C3 and C4, and immunoglobulin (Ig) M, as well as positive acute phase proteins, haptoglobin, α1-antitrypsin, α1 and α2 macroglobulin[doi.org] Also, depression was accompanied by an increased number of activated T cells (CD25 and HLA-DR ), secretion of neopterin, prostaglandin E2 and thromboxane.[doi.org]

  • IgE Myeloma

    The intrinsic tryptophan spectra showed an increase in the maximum fluorescence value over time ( Figure 5C ), indicating that, as a consequence of structural rearrangements[journals.plos.org] It is associated with an increased frequency of undetectable or small monoclonal (M)-protein levels on electrophoresis; osteolytic lesions; extramedullary involvement; amyloidosis[cancernetwork.com] The aggregation is accompanied by structural rearrangements which decrease the solvent exposure of tryptophan residues ( Figure 5C ) and increase the protein β-sheet content[journals.plos.org]

  • Schizophrenia

    Females with IBS have abnormal increased tryptophan degradation along the kynurenine pathway due to upregulation by proinflammatory cytokines.[doi.org] Preliminary analysis indicates an increased rate of immunoglobulin (Ig) M (but not IgG) class antibodies to Toxoplasma gondii in mothers with infants in whom schizophrenia[wwwnc.cdc.gov] ., l -tryptophan and l -5-hydroxytryptophan) and drugs that increase 5-HT release (e.g., fenfluramine and p -chloroamphetamine), and therefore the behavior is not specific[ncbi.nlm.nih.gov]

  • Biliary Tract Infection

    Several variants of this gene have been implicated in the increased risk of bile duct cancer, including a substitution of arginine for tryptophan at position 194 (R194W),[cco.amegroups.com] Hypergammaglobulinaemia occurs in a third of patients and immunoglobulin M (IgM) levels are increased in 50% of patients with advanced disease.[ncbi.nlm.nih.gov] […] which was associated with an increased risk of bile duct cancer (OR: 1.9; 95% CI: 1.1–3.5, P 0.03), and a substitution of arginine for histidine (R280H) variant, which was[cco.amegroups.com]

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