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15 Possible Causes for Impaired Exercise Tolerance, Macrocytic Anemia, Night Sweats

  • Myelodysplasia

    Medical Importance The myelodysplastic syndromes are clonal hematopoietic disorders that commonly cause macrocytic anemia in older patients.[hematology.org] Signs of transformation to a more aggressive lymphoma include worsening constitutional symptoms (weakness, fatigue, fever, weight loss, night sweats); rapidly enlarging lymph[iwmf.com] Initial stages of MDS may be characterized by macrocytic anemia with mild thrombocytopenia or neutropenia.[symptoma.com]

  • Inflammatory Bowel Disease Type 1

    Subjects were excluded if there was a known history of iron deficiency anemia (IDA), 14 UC, or macrocytic anemia.[doi.org] Crohn's Disease Symptom Tips Fever and night sweats can be Crohn's symptoms. Talk with your doctor to be sure.[web.archive.org] Vitamin B12 and folate deficient anemia is characteristically macrocytic.[doi.org]

  • Primary Myelofibrosis

    Constitutional symptoms, such as night sweats, pruritus, weight loss and fever may be treated with Jakafi.[mpnresearchfoundation.org] No new therapeutic intervention was initially required; however, 2 years later, the patient reported symptomatic splenomegaly and drenching night sweats, so ruxolitinib therapy[ncbi.nlm.nih.gov] Night sweats. Weight loss. Certain factors affect prognosis (chance of recovery) and treatment options for primary myelofibrosis.[navigatingcare.com]

  • Anemia

    Macrocytic anemia Possible causes of macrocytic anemia include vitamin B-12 deficiency, folate deficiency, liver disease, and hypothyroidism.[emedicine.com] Consider constitutional symptoms of chronic illnesses (eg, weight loss, night sweats, rashes, bowel changes).[emedicine.com] […] include fatigue, pallor, tachycardia, poor exercise tolerance, and suboptimal work performance. 14 Depleted blood reserves during delivery may increase the need for blood[bloodjournal.org]

  • Acute Myelocytic Leukemia

    Macrocytic anemia will be present unless there is an associated iron deficiency. Peripheral blood smear shows megaloblastic changes. Serum vitamin B12 levels are low.[online.epocrates.com] sweats easy bruising or petechiae (tiny red spots on the skin caused by easy bleeding) bone and joint pain belly pain (caused by the build-up of cells in organs like the[kidshealth.org] anemia, normal to increased platelet count, and increased numbers of megakaryocytes, many of which have hypolobated nuclei.[dx.doi.org]

  • Myeloproliferative Disease

    , such as macrocytic red blood cells.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] sweats Potential abdominal discomfort due to splenomegaly What does the peripheral blood look like in someone with CML?[quizlet.com]

  • Chronic Myeloid Leukemia

    anemia, normal to increased platelet count, and increased numbers of megakaryocytes, many of which have hypolobated nuclei.[doi.org] Patients usually present with fatigue, weight loss, anemia, night sweats, and splenomegaly.[icd9data.com] On initial presentation she reported fatigue, night sweats, and early satiety, and was found to have a white blood cell (WBC) count of 69.3 109 /L and platelet count of 366[ncbi.nlm.nih.gov]

  • Philadelphia Chromosome Positive Chronic Myeloid Leukemia

    Case report A 71-year-old female was referred the Clinic of Hematology, in November 2007 for evaluation of the macrocytic anemia of one year duration that failed to respond[omicsonline.org] Weight loss, fever, night sweats, and reduced exercise tolerance are common complaints.[symptoma.com] sweats or splenomegaly.[orpha.net]

  • Chronic Myelomonocytic Leukemia

    At the age of 83 (t   0), he started complaining of general weakness and a blood test showed profound macrocytic anemia, with no other cytopenia (Hb   7.2 g/dL; MCV   104[ojrd.biomedcentral.com] He had no symptoms of night sweats, fever, or weight loss. Review of his medical records showed a progressively increasing leukocytosis with a peak of 58 109/L.[ncbi.nlm.nih.gov] anemia, normal to increased platelet count, and increased numbers of megakaryocytes, many of which have hypolobated nuclei.[doi.org]

  • Myasthenia Gravis

    Side effects include dose dependent myelosuppression with macrocytic anemia, leukopenia, and thrombocytopenia, toxic hepatitis, and alopecia.[ncbi.nlm.nih.gov] sweats, stuttering speech, and blurred vision.[sciencerepository.org] […] bilateral lower extremity weakness which progressed to his upper extremities with muscle aches and a cold, burning sensation in his legs, followed by chronic cough and dyspnea, night[sciencerepository.org]

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