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10 Possible Causes for Impaired Exercise Tolerance, Monocytes Decreased, Peripheral T Cells Decreased

  • Aplastic Anemia

    MATERIALS AND METHODS: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3 - CD16[] CD56 NK cells, CD3 CD57 T-LGL cells and CD19 B lymphocytes were detected by flow cytometry.[] KEY FINDINGS: The CD4 /CD8 ratio decreased in the AA and hypo-MDS groups, and the difference was statistically significant when compared with that in the control group (P[]

  • Chronic Phase of Chronic Myeloid Leukemia

    The proportion of natural killer cells and cytotoxic T cells in peripheral lymphocytes increased after switching to dasatinib.[] In contrast, the proportion of regulatory T cells decreased during treatment. The safety profile of dasatinib was consistent with previous studies.[]

  • Severe Aplastic Anemia

    Results showed that the percentage of CD4 effector T cells in peripheral blood and bone marrow lymphocytes was decreased in SAA patients.[] The percentage of CD8 effector T cells in peripheral blood and CD8 central memory T cells in the bone marrow lymphocytes was significantly higher in newly diagnosed patients[] The ratio of CD4 memory T lymphocytes to CD8 memory T subsets (CD4 /CD8 TM) in SAA patients was also lower.[]

  • Asthma

    […] mediator release from mast cells, monocytes, and T lymphocytes.[] RT‑qPCR demonstrated that VDR expression in the peripheral blood of asthmatic children was decreased.[] […] plasma exudation 141 as well as inhibition of mediator release from smooth muscle cells, 93, 94 mast cells, 142 eosinophils, 143 monocytes, 144 and lymphocytes. 145 A number[]

  • Chronic Fatigue Syndrome

    […] of human monocytes to dexamethasone: potential regulation of the glucocorticoid receptor.[] […] ratio, indicating a T H 2 shift. 50 When peripheral blood mononuclear cells from CFS patients are stimulated in culture, increased IL-4 levels accompany a high T H 2/T H 1[] Subjective reports of PEM and prolonged recovery are supported by objective evidence, including failure to normally reproduce exercise test results (2-day CPET) and impaired[]

  • Viral Myocarditis

    Inhibition of microRNA-155 by a systemically delivered LNA-anti-miR attenuated cardiac infiltration by monocyte-macrophages, decreased T lymphocyte activation, and reduced[] Helper-inducer T cells (Lyt 1 cells) decreased significantly on day 7, but there was no change in cytotoxic-suppressor T cells in the peripheral blood.[] The lymphocyte subset in the peripheral blood was measured by flow cytometry and, T cell subset in the myocardium was stained by labeled avidin-biotin technique.[]

  • Follicular Lymphoma

    Given the negative differential outcomes in patients with decreased tumor-infiltrating lymphocytes and increased monocyte/macrophage activation, immunologic approaches in[] In this context, it may be a potentially important observation that the fraction of circulating Tregs, the most important cell population to maintain peripheral tolerance,[] 46 decreased in all analyzed patients.[]

  • Systemic Lupus Erythematosus

    […] macrophages as a serum-dependent defect that is associated with decreased levels of C1q, C4, and C3 [ 22 ].[] Decreased T cell precursor frequencies to Epstein–Barr virus glycoprotein Gp110 in peripheral blood correlate with disease activity and severity in patients with rheumatoid[] exercise tolerance are nonspecific.[]

  • Multiple Sclerosis

    Glatiramer acetate increases IL-1 receptor antagonist but decreases T cell-induced IL-1β in human monocytes and multiple sclerosis.[] Immunologic changes included a marked decrease in proliferation of interferon γ–producing myelin-reactive CD4 T cells in peripheral blood and decreased titers of myelin-specific[] This article reviews the literature related to MS and physical exercise. Physical exercise depends on patients' physiological tolerance and response to exercise.[]

  • Septic Shock

    These beneficial effects may be attributable to the direct adsorption of endotoxin, monocytes, activated neutrophils, and anandamide, as well as indirect decrease in inflammatory[] Brain injury can lead to stroke and thought impairment. Heart and lung damage can lead to significant disabilities that may include reduced exercise tolerance.[] The patient presented a remarkable cell activation profile and diminished percentage of peripheral blood T regulatory cells.[]

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