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17 Possible Causes for Impaired Exercise Tolerance, Peripheral T Cells Decreased

  • Asthma

    RT‑qPCR demonstrated that VDR expression in the peripheral blood of asthmatic children was decreased.[] […] and Tcell epitopes and the RasMol and 3DLigandSite were used to analyze the tertiary structure of VDR.[] […] software immune epitope database and analysis resource, SYFPEITHI and linear epitope prediction based on propensity scale and support vector machines were used to predict the B‑cell[]

  • Chronic Fatigue Syndrome

    Subjective reports of PEM and prolonged recovery are supported by objective evidence, including failure to normally reproduce exercise test results (2-day CPET) and impaired[] […] ratio, indicating a T H 2 shift. 50 When peripheral blood mononuclear cells from CFS patients are stimulated in culture, increased IL-4 levels accompany a high T H 2/T H 1[] Summary PEM is a worsening of a patient’s symptoms and function after exposure to physical or cognitive stressors that were normally tolerated before disease onset.[]

  • Graves Disease

    Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[] Central and peripheral tolerance and Th1 cells appeared to be associated with the pathogenesis of GD in 22qDS.[]

  • Aplastic Anemia

    MATERIALS AND METHODS: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3 - CD16[] CD56 NK cells, CD3 CD57 T-LGL cells and CD19 B lymphocytes were detected by flow cytometry.[] KEY FINDINGS: The CD4 /CD8 ratio decreased in the AA and hypo-MDS groups, and the difference was statistically significant when compared with that in the control group (P[]

  • Pulmonary Tuberculosis

    […] expression in peripheral blood Vγ2Vδ2 T cells (p   0.043, 0.026).[] A high lesion severity score was correlated with a decreased Vδ2 T cell number and increased Vγ2Vδ2 T cells Fas/FasL expression leve in the peripheral blood (p   0.00, P CONCLUSION[] : Compared with IGRA-positive TB patients, the IGRA-negative TB patients had more lesion severity scores, the number of Vγ2Vδ2 T cells decreased and the function of secreting[]

  • Follicular Lymphoma

    In this context, it may be a potentially important observation that the fraction of circulating Tregs, the most important cell population to maintain peripheral tolerance,[] 46 decreased in all analyzed patients.[] In contrast, a vaccination-induced increase of Tregs was strongly associated with failure of idiotype vaccination to induce an effector T-cell response in myeloma patients[]

  • Chronic Phase of Chronic Myeloid Leukemia

    The proportion of natural killer cells and cytotoxic T cells in peripheral lymphocytes increased after switching to dasatinib.[] In contrast, the proportion of regulatory T cells decreased during treatment. The safety profile of dasatinib was consistent with previous studies.[]

  • Viral Myocarditis

    Helper-inducer T cells (Lyt 1 cells) decreased significantly on day 7, but there was no change in cytotoxic-suppressor T cells in the peripheral blood.[] The lymphocyte subset in the peripheral blood was measured by flow cytometry and, T cell subset in the myocardium was stained by labeled avidin-biotin technique.[]

  • Severe Aplastic Anemia

    Results showed that the percentage of CD4 effector T cells in peripheral blood and bone marrow lymphocytes was decreased in SAA patients.[] The percentage of CD8 effector T cells in peripheral blood and CD8 central memory T cells in the bone marrow lymphocytes was significantly higher in newly diagnosed patients[] The ratio of CD4 memory T lymphocytes to CD8 memory T subsets (CD4 /CD8 TM) in SAA patients was also lower.[]

  • Peripartum Cardiomyopathy

    […] cytokine profile, decreased levels regulatory T cells and a significant reduction in the plasma levels of progesterone, estradiol and relaxin when compared with other normal[] These autoantibodies may cross-react with maternal myocardial proteins and lead to PPCM. [15] In addition, the peripheral blood from PPCM patients demonstrate an abnormal[]

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