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15 Possible Causes for Impaired Exercise Tolerance, Peripheral T Cells Decreased, Thrombocytopenia

  • Aplastic Anemia

    After the initial appearance of AMI approximately 2 months earlier, he had received conservative treatment/transfusion alone because of severe thrombocytopenia and anemia[ncbi.nlm.nih.gov] MATERIALS AND METHODS: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3 - CD16[ncbi.nlm.nih.gov] In women, this can lead to menorrhagia secondary to thrombocytopenia which may require treatment depending on its severity.[ncbi.nlm.nih.gov]

  • Chronic Phase of Chronic Myeloid Leukemia

    Transfusion of blood products is indicated to compensate for anemia and thrombocytopenia.[symptoma.com] The proportion of natural killer cells and cytotoxic T cells in peripheral lymphocytes increased after switching to dasatinib.[ncbi.nlm.nih.gov] Thrombocytopenia, hepatotoxicity, hyperbilirubinemia and hyperglycemia were the most common hematologic and non-hematologic adverse events (AEs).[haematologica.org]

  • Follicular Lymphoma

    Rituximab-induced acute thrombocytopenia is a rare side effect that has previously been reported in a small number of patients with malignant lymphoma; its mechanism is still[ncbi.nlm.nih.gov] In this context, it may be a potentially important observation that the fraction of circulating Tregs, the most important cell population to maintain peripheral tolerance,[doi.org] Rituximab-induced acute thrombocytopenia (RIAT), a rare complication of rituximab administration, has not yet been described in follicular lymphoma (FL).[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    Anemia most frequently causes fatigue, headaches and dizziness; thrombocytopenia provokes a tendency to bleed.[symptoma.com] Results showed that the percentage of CD4 effector T cells in peripheral blood and bone marrow lymphocytes was decreased in SAA patients.[ncbi.nlm.nih.gov] She recovered completely, but her thrombocytopenia persisted. Six weeks later she became pancytopenic. A bone marrow aspirate and biopsy showed severe aplastic anemia.[ncbi.nlm.nih.gov]

  • Lupus Erythematosus

    […] autoimmune thrombocytopenia).[merckmanuals.com] exercise tolerance are nonspecific.[journals.lww.com] Apoptosis rate increased in parallel to the drop-down of elevated CD5 CD19 cells. Peripheral T-cell subsets remained stable under low-dose MTX.[ncbi.nlm.nih.gov]

  • Graves Disease

    A 54-year-old woman suffering from pruritus for five years was diagnosed to have Graves' disease and immune thrombocytopenia (ITP) associated with primary biliary cirrhosis[ncbi.nlm.nih.gov] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] Anti-CD20 chimeric monoclonal antibody (rituximab) treatment of immune-mediated thrombocytopenia associated with Crohn's disease.[dx.doi.org]

  • Patent Ductus Arteriosus

    Contraindications: Thrombocytopenia NEC Bleeding diathesis Poor renal function Pulmonary haemorrhage (note: may occur because there is a PDA) Fluid restriction While on indomethacin[adhb.govt.nz] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] On the other hand, there are several contraindications for ibuprofen and indomethacin administration including thrombocytopenia, IVH, renal failure (due to decreased renal[bmrat.org]

  • Systemic Lupus Erythematosus

    Background While thrombopoeitin (TPO) agonists that act to simulate platelet production have been approved for use in steroid-refractory chronic immune thrombocytopenia purpura[ncbi.nlm.nih.gov] exercise tolerance are nonspecific.[journals.lww.com] Decreased T cell precursor frequencies to Epstein–Barr virus glycoprotein Gp110 in peripheral blood correlate with disease activity and severity in patients with rheumatoid[ncbi.nlm.nih.gov]

  • Peripheral Vascular Disease

    A diagnosis of consumptive thrombocytopenia secondary to peripheral vascular disease and platelet hyperaggregability was made.[ncbi.nlm.nih.gov] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] A 46 year old man with intermittent claudication due to severe peripheral vascular disease had a circulating lupus like anticoagulant (LLAC), thrombocytopenia (79 X 109/1)[ncbi.nlm.nih.gov]

  • Pulmonary Tuberculosis

    Most cases of thrombocytopenia in tuberculosis are moderate, and there are few reports about thrombocytopenia with diffuse alveolar hemorrhaging (DAH) in pulmonary tuberculosis[ncbi.nlm.nih.gov] […] expression in peripheral blood Vγ2Vδ2 T cells (p   0.043, 0.026).[ncbi.nlm.nih.gov] Tuberculosis and immune thrombocytopenia, Hematologica 2002; 87:(08) ELT 38. Yeaman MR. The role of platelets in antimicrobial host defense.[siicsalud.com]

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