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19 Possible Causes for Impaired Exercise Tolerance, Peripheral T Cells Decreased, Weakness

  • Graves Disease

    A 41-year-old female with history of Graves' disease, bilateral cataract, paroxysmal atrial fibrillation was admitted because of muscle weakness, daytime sleepiness, fatigability[ncbi.nlm.nih.gov] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] Although neuromuscular weakness is common in Graves' disease, coexisting myasthenia gravis (MG) is rare and can cause profound morbidity.[ncbi.nlm.nih.gov]

  • Aplastic Anemia

    Herein we report a patient with celiac disease who was not strictly following a gluten-free diet and presented with progressive pallor, fever, and weakness of 1 month's duration[ncbi.nlm.nih.gov] MATERIALS AND METHODS: A total of 41 patients with AA and 46 patients with hypo-MDS were collected, and the proportions of peripheral blood T lymphocyte subsets, CD3 - CD16[ncbi.nlm.nih.gov] A 66-year-old male visited our hospital with anemia and general weakness.[ncbi.nlm.nih.gov]

  • Severe Aplastic Anemia

    You end up feeling weak, tired, and short of breath. Anemia comes in many forms. Iron-deficiency anemia is most common.[webmd.com] Results showed that the percentage of CD4 effector T cells in peripheral blood and bone marrow lymphocytes was decreased in SAA patients.[ncbi.nlm.nih.gov] When you are anemic, your body does not transport oxygen efficiently and this can make you tired and weak. RBCs carry oxygen using a protein called hemoglobin.[healthline.com]

  • Peripheral Vascular Disease

    In addition to pain, affected individuals would also experience cramps, weakness and numbness in the area of reduced blood flow.Other symptoms of PVD include the following[symptoma.com] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] Symptoms Blockages can restrict blood flow to the muscles, causing muscle cramps, tightness or weakness, especially during activity.[cardiovascularcoalition.com]

  • Chronic Fatigue Syndrome

    […] six months or longer and (2) the coexistence of any four of a number of characteristic symptoms, defined as mild fever, sore throat, tender lymph nodes, muscle pain and weakness[britannica.com] Subjective reports of PEM and prolonged recovery are supported by objective evidence, including failure to normally reproduce exercise test results (2-day CPET) and impaired[nap.edu] […] ratio, indicating a T H 2 shift. 50 When peripheral blood mononuclear cells from CFS patients are stimulated in culture, increased IL-4 levels accompany a high T H 2/T H 1[ncbi.nlm.nih.gov]

  • Asthma

    At the same time, sodium cromoglycate was introduced, to be administered via the first dry-powder inhaler--the Spinhaler--but owing to its relatively weak anti-inflammatory[ncbi.nlm.nih.gov] RT‑qPCR demonstrated that VDR expression in the peripheral blood of asthmatic children was decreased.[ncbi.nlm.nih.gov] The anatomic weakness associated with the tracheal diverticulum could have been the breaking point of sustained increased pressure in the airways, due to a possible asthma[ncbi.nlm.nih.gov]

  • Pulmonary Tuberculosis

    A 26-year-old man, who had started treatment for pulmonary tuberculosis, developed polyarthralgia, generalised myalgia, weakness, and elevated uric acid and creatine kinase[ncbi.nlm.nih.gov] […] expression in peripheral blood Vγ2Vδ2 T cells (p   0.043, 0.026).[ncbi.nlm.nih.gov] Patient 1, a 20-year-old woman who had a past history of PTB, presented with weakness, numbness, and pain in the limbs.[ncbi.nlm.nih.gov]

  • Patent Ductus Arteriosus

    However, when the PDA is larger, it can result in more significant symptoms, including: Lethargy and weakness Fast or labored breathing Bounding (very strong) pulse Tachycardia[preemies.about.com] Pathogenesis • Escape from regulatory control of Helper T cells directed against these antigens • Defective intraocular T cell regulation of B cellsDecreased helper to[slideshare.net] Review question: How effective and safe are paracetamol, which has weak anti-inflammatory properties, compared with placebo (a substance with no active therapeutic effect)[cochrane.org]

  • Chronic Phase of Chronic Myeloid Leukemia

    If patients experience symptoms related to CP-CML, they may claim fatigue, malaise and weakness, early satiety and a feeling of fullness, possibly abdominal pain and weight[symptoma.com] The proportion of natural killer cells and cytotoxic T cells in peripheral lymphocytes increased after switching to dasatinib.[ncbi.nlm.nih.gov] Bruising Excessive sweating (night sweats) Fatigue Fever Pressure under the lower left ribs from a swollen spleen Rash -- small pinpoint red marks on the skin ( petechiae ) Weakness[medlineplus.gov]

  • Peripartum Cardiomyopathy

    If your heart muscle is weak, it can be hard for the heart to deliver blood to the body.[intermountainhealthcare.org] […] cytokine profile, decreased levels regulatory T cells and a significant reduction in the plasma levels of progesterone, estradiol and relaxin when compared with other normal[joacc.com] If you have peripartum cardiomyopathy, your heart becomes weak and larger than normal.[my.clevelandclinic.org]

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