Create issue ticket

69 Possible Causes for Inappropriate Insulin Secretion

  • Hypoglycemia

    Abstract Congenital hyperinsulinemic hypoglycemia (CHH) is characterized by the inappropriate secretion of insulin from pancreatic beta cells in the presence of hypoglycemia[ncbi.nlm.nih.gov] Causes/Pathophysiology : Unknown beta-cell abnormality leads to inappropriate insulin secretion. Treatment : Glucose in mild cases.[pedclerk.bsd.uchicago.edu]

  • Insulin Resistance

    In addition, this index does not take into account the inappropriately low insulin secretion in the face of hyperglycemia seen in diabetic subjects or glucose-intolerant subjects[doi.org] These data illustrate that the HOMA model of β-cell function reflects insulin secretion rather than β-cell “health.”[doi.org] Thus, linear correlations between 1/(fasting insulin) and estimates of insulin sensitivity from the glucose clamp are not that strong.[doi.org]

  • Polycystic Ovary Syndrome

    Characterization of the inappropriate gonadotropin secretion in polycystic ovary syndrome. J Clin Invest 1976 ;57: 1320 - 1329 12.[doi.org] […] gonadotropin secretion (elevated levels of circulating luteinizing hormone), 11 and insulin resistance with accompanying compensatory hyperinsulinemia. 12 Targeting these[doi.org] Profound peripheral insulin resistance, independent of obesity, in polycystic ovary syndrome. Diabetes 1989 ;38: 1165 - 1174 13.[doi.org]

  • Hyperinsulinism due to Glucokinase Deficiency

    insulin secretion in pancreatic β-cells, even when blood glucose is low.[biochemsoctrans.org] Leads to inappropriate insulin secretion even in the face of low plasma glucose concentrations In the absence of functional K ATP channels, plasma membrane is depolarized[unboundmedicine.com] […] release, characterized by an excessive/ uncontrolled insulin secretion (inappropriate for the ... 1 ...[familydiagnosis.com]

  • Diabetes Mellitus

    […] action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion.[emedicine.medscape.com] Chlorpropamide also causes the syndrome of inappropriate ADH secretion.[msdmanuals.com] […] inadequate insulin secretion, and excessive or inappropriate glucagon secretion.[emedicine.medscape.com]

  • Diabetes Mellitus Type 2

    […] action, inadequate insulin secretion, and excessive or inappropriate glucagon secretion.[emedicine.medscape.com] However, not all people with insulin resistance develop diabetes, since an impairment of insulin secretion by pancreatic beta cells is also required.[en.wikipedia.org] […] inadequate insulin secretion, and excessive or inappropriate glucagon secretion.[emedicine.medscape.com]

  • Drug-induced Hypoglycemia

    The mechanisms behind these side-effects are not known, but in hypoglycemia we describe signs of inappropriate insulin secretion.[ncbi.nlm.nih.gov]

  • Pancreatic Neoplasm

    About 5% to 8% are associated with MEN-1 syndrome.[ 4 ] The clinical manifestations are those of hypoglycemia, which results from inappropriate secretion of insulin by the[web.archive.org]

  • Insulin Increased

    […] and excess insulin secretion from the beta cells of the pancreas.[chop.edu] Inappropriate secretion, associated with hypoglycemia [ edit ] Hyperinsulinism may also refer to forms of hypoglycemia caused by excessive insulin secretion.[en.wikipedia.org] Diffuse KATP HI Focal KATP HI GDH-HI Glucokinase HI HNF1a and 4a Defects MCT-1 HI SCHAD-HI UCP-2 HI Congenital hyperinsulinism is caused by genetic mutations that result in inappropriate[chop.edu]

  • Glucagonoma

    In 1971, he developed peptic ulcer disease and symptoms of fasting hypoglycemia; inappropriate secretion of insulin was shown.[annals.org]

Further symptoms