Inappropriate Laughter: Causes & Reasons

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Possible Causes for Inappropriate Laughter

Angelman Syndrome

Angelman syndrome is characterized by mental retardation, seizures, ataxia, inappropriate laughter, lack of speech, a particular facial appearance, and generally a chromosome [ncbi.nlm.nih.gov]

laughter and happy disposition. [ncbi.nlm.nih.gov]

Given the patient's relatively mild developmental impairment, without clinical evidence of seizures, gait disturbance or inappropriate laughter, the diagnosis of AS was not [ncbi.nlm.nih.gov]

Pick Disease of The Brain

laughter 0000748 Irritability Irritable 0000737 Language impairment 0002463 Neuronal loss in central nervous system Loss of brain cells 0002529 Perseveration 0030223 Personality [rarediseases.info.nih.gov]

0000006 Disinhibition 0000734 Echolalia Echoing another person's speech 0010529 Emotional blunting 0030213 Frontotemporal dementia 0002145 Gliosis 0002171 Hyperorality 0000710 Inappropriate [rarediseases.info.nih.gov]

Schizophrenia

laughter or crying Oversleeping or insomnia; forgetful, unable to concentrate Odd or irrational statements; strange use of words or way of speaking While these warning signs [helpguide.org]

[…] social withdrawal Hostility or suspiciousness, extreme reaction to criticism Deterioration of personal hygiene Flat, expressionless gaze Inability to cry or express joy or inappropriate [helpguide.org]

Temporal Lobe Epilepsy

The distribution of granule cells in the dentate gyrus of the hippocampal formation was studied in control autopsy and temporal lobe epilepsy (TLE) specimens. In control tissue, the granule cell somata were closely approximated and formed a narrow lamina with a distinct, regular border with the molecular layer. In 11[…] [ncbi.nlm.nih.gov]

Hallucinogen

This is often referred to as “skittling,” “robotripping,” or “dexing,” the DEA Inappropriate laughter, feelings of floating, altered sense of touch and hearing, hallucinations [solutions-recovery.com]

Disorganized Schizophrenia

Inappropriate facial responses may be common, and behavior is sometimes described as "silly", such as inappropriate laughter. [en.wikipedia.org]

Symptoms of / Reasons for Hebephrenic Schizophrenia Inappropriate laughter Delusions Lack of motivation Bizarre emotional responses [gomentor.com]

[…] or inappropriate laughter, and incoherent thought and speech. [britannica.com]

Frontotemporal Dementia

Frontotemporal dementia (FTD) is a heterogeneous disorder with distinct clinical phenotypes associated with multiple neuropathologic entities. Presently, the term FTD encompasses clinical disorders that include changes in behavior, language, executive control, and often motor symptoms. The core FTD spectrum disorders[…] [ncbi.nlm.nih.gov]

Lysergic Acid Diethylamide Poisoning

ICD-10-CM Codes › S00-T88 Injury, poisoning and certain other consequences of external causes › T36-T50 Poisoning by, adverse effect of and underdosing of drugs, medicaments and biological substances › T40- Poisoning by, adverse effect of and underdosing of narcotics and psychodysleptics [hallucinogens] ›[…] [icd10data.com]

Temporal Lobe Disorder

John Libbey Eurotext, 2005 - 289 من الصفحات Much has been written about the cognitive function of children with epilepsy but despite there being extensive study of the neuropsychological status of adults with intractable temporal lobe epilepsy, it has been more limited in children. Although cognitive development in[…] [books.google.com]

Primary Amebic Meningoencephalitis

« Previous Article Table of Contents Next Article » Abstract Fulltext Figs (1) References (6) Cited By (8) Supplementary Material (0) Metrics Related Content Preview this: Primary amoebic meningoencephalitis: amoebicidal effects of clinically approved drugs against Naegleria fowleri, Page 1 of 1 < Previous page |[…] [jmm.microbiologyresearch.org]

Psilocybine

[…] human TDLo intramuscular 75ug/kg (0.075mg/kg) BEHAVIORAL: EUPHORIA BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" Psychopharmacologia Vol. 3, Pg. 219, 1962. human TDLo intramuscular 130ug/kg (0.13mg/kg) BEHAVIORAL: "HALLUCINATIONS, DISTORTED PERCEPTIONS" BEHAVIORAL: TOXIC PSYCHOSIS Proceedings of the European[…] [chem.nlm.nih.gov]

Anaesthetic Induction Agent

Abstract Etomidate is a new non-barbiturate intravenous (i.v.) anaesthetic induction agent. This paper attempts to evaluate its overall safety based on studies on its effects on the cardiovascular and respiratory systems, intraocular pressure changes, apgar scores of newborns, plasma potassium changes and times[…] [ncbi.nlm.nih.gov]

Uniparental Disomy

They may have seizures and often have inappropriate outbursts of laughter. [healthlibrary.uchospitals.edu]

Christianson Syndrome

laughter 0000748 Microcephaly Abnormally small skull Decreased circumference of cranium Decreased size of skull Reduced head circumference Small head circumference [ more [rarediseases.info.nih.gov]

[…] in infancy 0008872 Gait ataxia Inability to coordinate movements when walking 0002066 Gastroesophageal reflux Acid reflux Acid reflux disease Heartburn [ more ] 0002020 Inappropriate [rarediseases.info.nih.gov]

Adenylosuccinate Lyase Deficiency

Always she used to remain happy and cheerful with frequent excessive, inappropriate laughter. [pediatricneurosciences.com]

laughter), aggressive behavior, temper tantrums, impulsivity, hyperactivity, short attention span, and hypersensitivity to noise and lights. [rarediseases.info.nih.gov]

Behavioral abnormalities, including hyperactivity, self and hetero-aggressiveness, inappropriate laughter were frequently reported, particularly in type I. [ojrd.biomedcentral.com]

Classic Progressive Supranuclear Palsy Syndrome

Ups and downs, “roller coaster” emotions In PSP emotional lability, or pseudobulbar affect, may occur and is characterized by sudden or inappropriate laughter or inconsolable [movementdisorders.ufhealth.org]

Macrocephaly - Intellectual Disability - Autism

laughter Aggressive behavior Impulsivity Hyperactivity Short attention span Poor eye contact Brain tumor (astrocytoma) Benign adrenal gland tumor (adrenal adenoma) Abnormality [undiagnosed.hms.harvard.edu]

MR, absent speech, microcephaly, seizures, puppetlike ataxic movements, inappropriate laughter, and facial dysmorphisms characterize AS. [misc.medscape.com]

Developmental regression Intellectual disability Autism spectrum disorder Absent speech Overeating (polyphagia) Sleep disturbance Self-mutilation and injurious behavior Pica Inappropriate [undiagnosed.hms.harvard.edu]

Disproportionate Short Stature - Ptosis - Valvular Heart Lesions

laughter) Hyperexcitability, short attention span Fascination with water Treatment Prognosis : Life expectancy is typically normal. [amboss.com]

[…] movements of the limbs Truncal hypotonia, limb hypertonia, hyperreflexia Difficulty sleeping Intellectual disability Characteristic happy demeanor with frequent laughing (inappropriate [amboss.com]

Colobomatous Microphthalmia - Rhizomelic Dysplasia Syndrome

laughter - MR, speech delay - AD inheritance - bilateral coronal craniosynostosis (tall shortened head) - developmental delay and MR - syndactyly - brachycephaly - maxillary [quizlet.com]

[…] prominent forehead, midfacial hypoplasia - maternal 15q11-13 microdeletion - "happy puppet", jerky and ataxic - hypotonia - midface hypopasia - prognathism - seizures - inappropriate [quizlet.com]

Acute Rheumatic Endocarditis

laughter If your child has a fever, they might require immediate care. [healthline.com]

[…] fever sweating vomiting a flat, slightly raised, ragged rash jerky, uncontrollable movements of the hands, feet, and face a decrease in attention span outbursts of crying or inappropriate [healthline.com]

Acanthopanacis

This herb is increasingly being used for symptoms of Deficiency such as; general weakness, malaise, anorexia, headache, insomnia, inappropriate laughter, frustration, fearfulness [americandragon.com]

Severe Neonatal-Onset Encephalopathy with Microcephaly

laughter mapped to chromosome 15q11 and ascribed to deletion, uniparental disomy, and mutations of either the imprinting centre or the UBE3A gene. 8 Considering that RTT [jmg.bmj.com]

[…] pattern in circulating white blood cells of healthy female carriers. 6 7 Angelman syndrome (AS) is an epileptic encephalopathy with microcephaly, absent speech, ataxia, and inappropriate [jmg.bmj.com]

Hypotonia-Failure to Thrive-Microcephaly Syndrome

Additional Information Angelman syndrome (AS) is characterized by severe developmental delay/mental retardation, absence of speech, ataxic gait, inappropriate laughter, hand-flapping [integratedgenetics.com]

Inappropriate laughter. Cri du Chat Syndrome Chromosomal 5p-, deletion of the long arm of chromosome 5. "Cry of the cat." [kumc.edu]

Paranoid Schizophrenia

Disorganized Schizophrenia – child-like and repetitive behaviors, inappropriate laughter, and incoherent speech. [disability-benefits-help.org]

laughter or crying Oversleeping or insomnia; forgetful, unable to concentrate Odd or irrational statements; strange use of words or way of speaking While these warning signs [helpguide.org]

Marfanoid Habitus with Situs Inversus

Deletion of Maternal allele 15q12: mental retardation, seizures, ataxia, inappropriate laughter "happy puppet". [quizlet.com]

laughter (Angel!) [brainscape.com]

Inappropriate laughter, seizures, ataxia and severe intellectual disability X linked dominant- examples Hypophosphatemic rickets, fragile x, alport sx. [studystack.com]

Prader-Willi Syndrome

laughter, and seizures. [jfmpc.com]

They may have seizures and often have inappropriate outbursts of laughter. [urmc.rochester.edu]

15q11-13, paternal uniparental disomy or epigenetic silencing of the maternal E3A gene. [9] These children have more pronounced neurobehavioral abnormalities - seizures, inappropriate [jfmpc.com]

Short Stature and Facio-Auriculo-Thoracic Malformations

laughter Adducted thumb Neuronal loss in central nervous system Urinary incontinence X-linked dominant inheritance Epileptic encephalopathy Intellectual disability, profound [mendelian.co]

[…] lentis Anteverted nares Muscular hypotonia Abnormality of lower limb joint Broad femoral metaphyses Osteochondroma Camptodactyly of toe Increased serum lactate Tetraparesis Inappropriate [mendelian.co]

Absent Thumb - Short Stature - Immunodeficiency Syndrome

Inappropriate laughter. Cri du Chat Syndrome Chromosomal 5p-, deletion of the long arm of chromosome 5. "Cry of the cat." [kumc.edu]

Say Barber Miller Syndrome

laughter, short stature and seizures. [pubcasefinder.dbcls.jp]

The newly described 2q23.1 microdeletion syndrome includes severe intellectual deficit with pronounced speech delay, behavioral abnormalities including hyperactivity and inappropriate [pubcasefinder.dbcls.jp]

Congenital Malformation Syndromes Involving Early Overgrowth

Sleep-wake cycle disturbance Split hand Triphalangeal thumb Overfolded helix Broad hallux Rocker bottom foot Aniridia Ectrodactyly Split foot Amniotic constriction ring Inappropriate [mendelian.co]

laughter Hand oligodactyly Red hair Foot oligodactyly Absent hand Attached earlobe Morphological abnormality of the middle ear Bilateral triphalangeal thumbs Tongue thrusting [mendelian.co]

[…] zygomatic bone Abnormality of the skull Limb tremor Umbilical hernia Low-set, posteriorly rotated ears Oligodactyly Abnormality of the pinna Cleft lip Paroxysmal bursts of laughter [mendelian.co]