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76 Possible Causes for Incidence of Hepatocellular Carcinoma Increased, Pruritus

  • Cholelithiasis

    The incidence of ICC is relatively low but increasing worldwide [ 4, 5 ]. The risk factors for ICC are complex.[bmccancer.biomedcentral.com] Steatorrhea, dark amber urine, constipation, jaundice, clay colored stools, pruritus (itchy) Lab values WBC count elevated (leukocytosis) normal is 5-10K, liver function studies[quizlet.com] .• If obstruction is present, the patient may complain of fever, clay-colored stool, tea-colored urine, jaundice, nausea and vomiting, pruritus, and symptoms specific to pancreatitis[scribd.com]

  • Hepatocellular Carcinoma

    The incidence of hepatocellular carcinoma increased with serum HBV DNA level at study entry in a dose-response relationship ranging from 108 per 100,000 person-years for an[ncbi.nlm.nih.gov] […] reported adverse events included aspartate aminotransferase increase (19%); rash (17%); elevation of alanine aminotransferase (15%), lipase (17%) and amylase (15%); and pruritus[healio.com] There was no history of altered bowel habits, clay coloured stools, hematemesis, malena, pruritus or alcohol consumption.[cancerjournal.net]

  • Liver Cirrhosis

    El-Serag HB, Davila JA, Petersen NJ, McGlynn KA (2003) The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update.[doi.org] Severe pruritus may require treatment with ultraviolet light or plasmapheresis.[patient.info] El-Serag HB (2012) Epidemiology of viral hepatitis and hepatocellular carcinoma. Gastroenterology 142 : 1264–1273. [ PMC free article ] [ PubMed ] [ Google Scholar ] 2.[ncbi.nlm.nih.gov]

  • Cholestasis

    Hepatocellular carcinoma, once a relatively uncommon tumor, has been increasing in incidence since the 1990s because of its association with hepatitis C–induced cirrhosis.[clevelandclinicmeded.com] Intractable pruritus of cholestasis leads to significant morbidity.[ncbi.nlm.nih.gov] Abstract Accumulation of bile acids can lead to invalidating pruritus in cholestatic patients.[ncbi.nlm.nih.gov]

  • Primary Sclerosing Cholangitis

    Hepatocellular carcinoma, once a relatively uncommon tumor, has been increasing in incidence since the 1990s because of its association with hepatitis C–induced cirrhosis.[clevelandclinicmeded.com] Jaundice and pruritus. Right upper quadrant abdominal pain. Fatigue, weight loss, fevers and sweats.[patient.info] Primary sclerosing cholangitis (PSC) is a chronic inflammatory disease of bile ducts..Patients with PSC usually presents with fatigue, jaundice and pruritus.[ncbi.nlm.nih.gov]

  • Hepatitis

    El-Serag HB, Davila JA, Petersen NJ, McGlynn KA: The continuing increase in the incidence of hepatocellular carcinoma in the United States: an update.[doi.org] When they persist, they cause prolonged jaundice, elevated alkaline phosphatase, and pruritus, despite general regression of inflammation.[merckmanuals.com] Pruritus and localised hepatic discomfort or pain may follow. 7 The duration of illness varies.[immunisationhandbook.health.gov.au]

  • Alcoholic Liver Disease

    However, the incidence of hepatocellular carcinoma (HCC) in alcoholic cirrhosis (AL-LC) clearly increased during this period.[ci.nii.ac.jp] […] hepatic mass jaundice palmar erythema cutaneous telangiectasia asterixis Other Factors ascites weight loss weight gain malnutrition and wasting anorexia fatigue confusion pruritus[online.epocrates.com] Symptoms include: jaundice portal hypertension , which increases blood pressure in the vein that travels through the liver skin itching (pruritus) Damage from repeated and[healthline.com]

  • Primary Biliary Cirrhosis

    There is no increased incidence of hepatocellular carcinoma. 5 Due to the destruction and disintegration of bile ducts, the disease can microscopically appear like vanishing[consultant360.com] Intense pruritus can be itself an indication to liver transplantation, in extreme cases leading to suicide.[ncbi.nlm.nih.gov] Hepatocellular carcinoma, once a relatively uncommon tumor, has been increasing in incidence since the 1990s because of its association with hepatitis C–induced cirrhosis.[clevelandclinicmeded.com]

  • Intrahepatic Cholangiocarcinoma

    The incidence of ICC is increasing globally [ 3 ].[karger.com] […] cholangiocarcinoma is a rare condition which typically occurs in males between 50 and 70 years of age, and presents with symptoms related to biliary obstruction including jaundice, pruritus[ncbi.nlm.nih.gov] Palliative therapy Relief of biliary obstruction is warranted when symptoms such as pruritus and hepatic dysfunction outweigh other symptoms of the cancer.[northshore.org]

  • Toxic Liver Disease

    […] of hepatocellular carcinoma, and death.[aafp.org] Cholestyramine may be used for alleviation of pruritus. Ursodeoxycholic acid may be used. Lastly, consulting a hepatologist is also helpful.[emedicine.medscape.com] Fatigue Weight loss Inability to concentrate Decreased libido Pruritus (in cholestatic liver diseases) Physical examination Perform a thorough physical examination with special[hiv.va.gov]

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