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175 Possible Causes for Increased Bone Marrow Megakaryocytes

  • Thrombocythemia 2

    Bone marrow biopsy with atypical megakaryocytes Bone marrow aspirate with atypical megakaryocytes Peripheral smear description Normal / mild increase in the white blood cell[pathologyoutlines.com] It is characterized by sustained thrombocytosis in the peripheral blood and increased numbers of large, mature megakaryocyte s in the bone marrow and clinically by the occurrence[seer.cancer.gov] It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage[icd10data.com]

  • Essential Thrombocythemia

    ET is usually characterized by a hypercellular bone marrow, including increased numbers of megakaryocytes.[labce.com] The bone marrow examination revealed increased numbers of dysmorphic megakaryocytes with focal clustering.[ncbi.nlm.nih.gov] It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage[icd9data.com]

  • Thrombocytosis

    It is characterized by sustained thrombocytosis in the blood, increased numbers of large, mature megakaryocytes in the bone marrow, and episodes of thrombosis and/or hemorrhage[icd9data.com] In primary thrombocytosis, megakaryocytes are produced in the bone marrow at an increased rate, no longer being controlled by the normal regulatory mechanisms.[labce.com] Diagnosis of essential thrombocytosis was considered in view of persistent thrombocytosis, antiphospholipid antibodies, bone marrow showing increased number, clusters and[ncbi.nlm.nih.gov]

  • Myelodysplastic Syndrome due to 5q Deletion

    marrow blasts, based on 500 nucleated cell differential If marrow blasts 5-19%, or Auer rods present, designate as RAEB Poor prognosis Bone marrow megakaryocytic hyperplasia[surgpathcriteria.stanford.edu] Normocellular bone marrow with increased numbers of small, hypolobated megakaryocytes.[emedicine.medscape.com] Bone marrow aspirate smears showed an increase in megakaryocytes, pseudo-Pelger–Huet cells, erythroid hypoplasia, erythrodysplasia in the form of mitosis and irregular nuclear[ijpmonline.org]

  • Acute Panmyelosis with Myelofibrosis

    Abstract Acute Panmyelosis with myelofibrosis is an exceedingly rare disorder characterized by a fibrotic bone marrow with an increased number of immature trilineage hematopoietic[scopemed.org] On admission, immature cells in the peripheral blood were increased and a bone marrow biopsy revealed myelofibrosis and a cluster of hypolobulated and/or nonlobulated megakaryocytes[annlabmed.org] […] with a poorly lobulated nucleus and dispersed chromatin, occasional neutrophils and late stage erythroblasts Bone marrow biopsy: Partial replacement of marrow by blasts and[pathologyoutlines.com]

  • Amegakaryocytic Thrombocytopenia

    […] of Bone Marrow Reactive Hematopoietic Changes Erythroid hyperplasia Myeloid Hyperplasia Eosinophilia Increased Number of Megakaryocytes Bone Marrow Hypoplasia and Aplasia[atlases.muni.cz] Repeated biopsies disclosed gradually decreasing numbers of megakaryocytes and increasing marrow hypoplasia.[ncbi.nlm.nih.gov] It is generally regarded as a manifestation of increased platelet destruction. 1-8 This conclusion is based upon the observation of normal to increased numbers of megakaryocytes[jamanetwork.com]

  • Myeloid Metaplasia

    increase in bone marrow megakaryocytes was only slight might explain the absence of bone marrow fibrosis in this case.[ncbi.nlm.nih.gov] All patients had clusters of abnormal megakaryocytes in bone marrow.[ncbi.nlm.nih.gov] Platelet are increased in size. The bone marrow is usually hypercellular at presentation with remarkably increased megakaryocytes and, to a lesser degree, granulocytes.[atlasgeneticsoncology.org]

  • Alpha-Thalassemia-Myelodysplastic Syndrome

    A previously healthy 66-year-old man presented with hemoglobin of 9.3 g/dL, mean corpuscular volume 59 fL, and a bone marrow aspirate with increased erythroid precursors and[ncbi.nlm.nih.gov] A previously healthy 66-year-old man presented with hemoglobin of 9.3 g/dL, mean corpuscular volume 59 fL, and a bone marrow aspirate with increased erythroid precursors and[ingentaconnect.com] […] hypolobulated megakaryocytes.[ncbi.nlm.nih.gov]

  • Immune Thrombocytopenic Purpura

    Thus, the patients were diagnosed as immune thrombocytopenic purpura due to the isolated thrombocytopenia, large platelets on blood and bone marrow smears and increased megakaryocytes[ncbi.nlm.nih.gov] Thrombocytopenia was refractory to platelet infusions and bone marrow aspiration revealed remission status for ALL along with increased megakaryocytes.[ncbi.nlm.nih.gov] In 1946, Dameshek and Miller studied bone marrow from patients with ITP and found an increase in the total number of megakaryocytes in the bone specimens, but the majority[doi.org]

  • Familial X-Linked Thrombocytosis

    Megakaryocytes were increased in number and size.[ncbi.nlm.nih.gov] In clonal thrombocythemia, bone marrow findings include increased numbers of megakaryocytes and other myeloid cells, abnormality in cell morphology, presence of megakaryocyte[ascopost.com] *Normal PTT/PT*; *increased bleeding time*. megakaryocytes in bone marrow.[quizlet.com]

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