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92 Possible Causes for Increased Risk of Myelodysplastic Syndrome or Leukemia

  • Basal Cell Carcinoma

    In addition, individuals with this disorder are at markedly increased risk of myelodysplastic syndrome, acute leukemia, and bone marrow failure.[cancer.gov]

  • Epithelial Ovarian Cancer

    Zejula is associated with serious risks, such as hypertension, severe increase in blood pressure (hypertensive crisis), bone marrow problems (myelodysplastic syndrome), a[fda.gov] […] type of cancer of the blood called acute myeloid leukemia and low levels of blood cells in the bone marrow (bone marrow suppression).Women who are pregnant or breastfeeding[fda.gov]

  • Leukemia

    […] or acute myeloid leukemia increases after chemotherapy.[cancertherapyadvisor.com] Certain genetic disorders can increase the risk; Down syndrome, Li-Fraumeni syndrome, and other medical conditions can increase the risk of developing leukemia.[medicinenet.com] Here are some common risk factors but the risk factors are different for specific types of leukemia: Radiation exposure Smokers have an increased risk of acute myeloid leukemia[consumerhealthdigest.com]

  • Pediatric Crohn's Disease

    Increased risk under anti-metabolites Increased risk under anti-TNF α Increased risk under anti-metabolite with anti-TNF α Non-Hodgkin lymphoma[ 33 - 35 ] Melanoma[ 42 ] Hepatosplenic[doi.org] Specific cancers thought secondary to long-standing immunosuppression in the setting of IBD include lymphomas, acute myeloid leukemia, myelodysplastic syndromes, skin cancers[doi.org] T-cell lymphoma[ 38 ] Acute myeloid leukemia and Myelodysplastic syndromes[ 61 ] Non-melanoma skin cancers (basal and squamous cell carcinomas)[ 39 - 41 ] Urinary tract cancers[doi.org]

  • Kostmann Syndrome

    With increasing age, you are at increased risk for myelodysplastic syndrome (MDS) and leukemia (mostly acute myeloid leukemia) compared to the general population.[verywell.com]

  • Refractory Anemia with Excess Blasts in Transformation

    Myelodysplastic syndromes (MDS) are a group of bone marrow diseases that have an increased risk of developing into acute myelogenous leukemia (AML).[verywell.com]

  • Familial Neutropenia

    There is increased risk for myelodysplastic syndrome and, rarely, acute myelogenous leukemia.[ncbi.nlm.nih.gov] Patients with severe congenital neutropenia exhibit an increased risk of developing a myelodysplastic syndrome or acute myelogenous leukemia – a consequence that has become[news-medical.net]

  • Crohn's Disease

    Increased risk under anti-metabolites Increased risk under anti-TNF α Increased risk under anti-metabolite with anti-TNF α Non-Hodgkin lymphoma[ 33 - 35 ] Melanoma[ 42 ] Hepatosplenic[doi.org] Specific cancers thought secondary to long-standing immunosuppression in the setting of IBD include lymphomas, acute myeloid leukemia, myelodysplastic syndromes, skin cancers[doi.org] T-cell lymphoma[ 38 ] Acute myeloid leukemia and Myelodysplastic syndromes[ 61 ] Non-melanoma skin cancers (basal and squamous cell carcinomas)[ 39 - 41 ] Urinary tract cancers[doi.org]

  • Lymphoma

    Some medical conditions (such as myelodysplastic syndromes) as well as previous chemotherapy increase risk.[lymphoma.about.com] Infection with the human T-cell leukemia virus (HTLV-1) is also a significant risk factor for leukemia, but is uncommon in the United States.[lymphoma.about.com]

  • Diamond-Blackfan Anemia

    risk of myelodysplastic syndrome (MDS), leukemia and solid tumors[seattlechildrens.org] People with this disorder are at increased risk for developing myelodysplastic syndrome, another bone marrow disorder, acute myeloid leukemia (AML), and a type of bone cancer[medicinenet.com] […] problems may include: A gap in the roof of their mouth ( cleft palate ) Differences in their bones Problems with their kidneys, heart, hormones or ability to fight infection Increased[seattlechildrens.org]

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