Possible Causes for increased susceptibility to infections Primary Immune Deficiency Disorder Abstract: Patients with primary immunodeficiency diseases most often are recognized because of their increased susceptibility to infection (chronic or recurrent infections [asmscience.org] susceptibility to infection. [lls.org] One of the most common signs of primary immunodeficiency is an increased susceptibility to infections. [fortishealthcare.com] Adrenal Cushing Syndrome An increased susceptibility to infection may also lead to sepsis. Hyperglycemia and hypertension are a common association as it was there in this case. [ijem.in] Increased susceptibility to infections. Affected children tend to be obese but grow slowly so are short for their age. How does Cushing's syndrome progress? [patient.info] susceptibility to some infections including pneumonia and TB. [nadf.us] Shwachman Syndrome Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections. [rarediseases.org] These may include increased tooth decay (dental caries), mouth ulcers, and/or disease of the tissues that surround and support the teeth (periodontal disease). [rarediseases.org] […] repeated bacterial infections, such susceptibility may vary from case to case, depending upon the degree of neutropenia and other immune factors that help the body to fight off infections [rarediseases.org] Lethal Ataxia with Deafness and Optic Atrophy susceptibility to infections / recurrent infections - Intellectual deficit / mental / psychomotor retardation / learning disability - Nerve conduction abnormality - Optic [csbg.cnb.csic.es] Levels of uric acid in blood were normal in all these four affected males, and none of them presented with increased susceptibility to infections. [doi.org] […] hyporeflexia - Ataxia / incoordination / trouble of the equilibrium - Death in infancy - Hemiplegia / diplegia / hemiparesia / limb palsy - Hypotonia - Immunodeficiency / increased [csbg.cnb.csic.es] Common Cold susceptibility to infections. [ingentaconnect.com] Some rhinovirus serotypes also upregulate ICAM-1 expression on human epithelial cells to increase susceptibility to infection. [emedicine.medscape.com] The general public and public health authorities should therefore keep this in mind and take appropriate measures to prevent increases in morbidity and mortality during winter [ingentaconnect.com] Vulvitis Women with diabetes may develop vulvitis because the sugar content of their cells is higher, increasing susceptibility to infection. [ourbodiesourselves.org] Women who have diabetes also have an increased risk of developing vulvitis because a high blood sugar content increases susceptibility to infections. [womenshealth.about.com] Vulvitis often accompanies vaginal infections. Stress, inadequate diet, and poor hygiene can increase the likelihood of vaginal infections. [ourbodiesourselves.org] Upper Respiratory Infection […] to infection. [ncbi.nlm.nih.gov] Publisher Full Text Can exercise affect immune function to increase susceptibility to infection? [unboundmedicine.com] The presence of upper respiratory infection is an additional factor increasing the susceptibility of small children to hypoxemia. [ncbi.nlm.nih.gov] Complement Factor D Deficiency […] by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway. [malacards.org] Properdin deficiency is also associated with increased susceptibility to infection with Neisseria organisms. [clinicaladvisor.com] Disorders of the complement cascade may or may not result in increased susceptibility to infections. [antimicrobe.org] Complement Deficiency Syndrome C3 27 Bacterial infections, SLE-like syndrome C4 26 SLE-like syndrome, encapsulated bacterial infections C1-INH 2-10:100,000 Angioedema MBL 2-7% UK population Increased susceptibility [sinobiological.com] susceptibility to infections, problems encountered depend on which pathway is affected. [icd10data.com] There are more than 150 PID diseases, and PID leads to increased susceptibility to infection. Most of the PIDs present with only B-cell defects (Fig 1). [pedsinreview.aappublications.org] Papillon Lefevre Disease Other symptoms of PLS may include pyogenic skin infections, nail dystrophy, hyperhidrosis, increased susceptibility to infection, and ectopic cranial calcifications (Laass [genedx.com] The disease is characterized by palmoplantar hyperkeratosis, loss of deciduous and permanent teeth and increased susceptibility to infections. [ncbi.nlm.nih.gov] susceptibility to infections in PLS patients is not clear, but it is attributed to the dysfunction in neutrophil motility to bacterial infection. [idoj.in] Immunodeficiency due to Ficolin 3 Deficiency Some patients may show increased susceptibility to infection in the perinatal or neonatal period, whereas others may show autoimmune features as adults. [diseaseinfosearch.org] Decreased MBL levels may be associated with increased susceptibility to infections when the adaptive immune system is immature (in early childhood) 12 or has been suppressed [labcorp.com] […] the overall susceptibility of an individual to infectious disease and predisposes to greater severity when infections occur. [labcorp.com] Viral Lower Respiratory Infection Contrary to what people may think, other factors, such as becoming chilled, wet, or tired, do not cause colds or increase a child's susceptibility to infection. [msdmanuals.com] Vaginal Candidiasis Use of spermicidal jellies and creams increases susceptibility to infection by altering the vaginal flora and increasing the adhesion of Candida organisms. [aafp.org] Causes Several factors increase susceptibility to yeast infections, particularly pregnancy, prolonged antibiotic use and perhaps birth control pills (still being debated). [healthcentral.com] Some of the risk factors that increase the susceptibility for a woman to develop vaginal Candida infection include: Antibiotic therapy Pregnancy Uncontrolled Diabetes Mellitus [myhealth.gov.my] Viral Upper Respiratory Tract Infection Consequently, external agents such as allergens and pollutants that damage airway epithelium could increase susceptibility to infection and/or lead to more-severe infections [intechopen.com] Contrary to what people may think, other factors, such as becoming chilled, wet, or tired, do not cause colds or increase a child's susceptibility to infection. [merckmanuals.com] susceptibility of the injured epithelial cells to viral infection ( Frampton et al., 2002 ). [intechopen.com] Bronchitis Try to avoid being around smokers because even secondhand smoke can make you more susceptible to viral infections and increase congestion in your airway. [brennerchildrens.org] Symptoms include labored breathing, the inability to forcefully blow air out of the lungs, and an increased susceptibility to respiratory tract infections. [medical-dictionary.thefreedictionary.com] Iron Deficiency Additionally, iron deficiency anemia is associated with an increased susceptibility to infections. [mayoclinic.org] susceptibility to infection Glossitis (an inflamed tongue) How is iron deficiency detected? [web.archive.org] The importance of nutritional immunity as it pertains to iron is exemplified by the increased susceptibility to infection of individuals with iron overload due to thalassemia [ncbi.nlm.nih.gov] Vitamin D Deficiency susceptibility to infections and respiratory symptoms. [gov.uk] Vitamin D deficiency may lead to a whole host of clinical conditions which impair health and increase mortality rates: increase susceptibility to bacterial and viral infections [ncbi.nlm.nih.gov] The effect of infections on susceptibility to autoimmune and allergic diseases. [doi.org] Vaginitis […] painful sexual intercourse bleeding after intercourse[7] painful urination[3] blood in the urine increased urinary frequency[3][6] incontinence increased susceptibility to [en.wikipedia.org] However, these factors may increase your susceptibility to infection. [health.gatech.edu] susceptibility to HIV infection.[11] To reduce the risk of reinfection, sexual partners of anyone with infectious cervicits should be referred for evaluation[12] or treated [en.wikipedia.org] Urinary Tract Infection A complicated UTI occurs in a person with an abnormal urinary tract or an increased susceptibility to infection. [doi.org] When women reach menopause, the decrease in estrogen thins the lining of the urinary tract, which increases susceptibility to bacterial infections. [sutterhealth.org] Susceptibility increases with longer duration and greater severity of diabetes. [emedicine.medscape.com] Anemia Symptoms you may experience: Fatigue, weakness, irritability, pale skin, headaches, brittle nails, decreased appetite, increased susceptibility to infections, and a decreased [gluten.org] It also increases susceptibility to infection, and the likelihood of experiencing weakness or fatigue symptoms. [povertyactionlab.org] Additionally, iron deficiency anemia is associated with an increased susceptibility to infections. [mayoclinic.org] Vitamin B12 Deficiency susceptibility to infections. [symptoma.com] susceptibility to infections Poor wound healing Malnutrition Enlarged spleen (splenomegaly) Enlarged liver (hepatomegaly) Skin hyper pigmentation or hypo pigmentation Poor [b12deficiency.info] susceptibility to infections Development of yellowish coloration of skin In more advanced stages, when the deficiency continues for a prolonged duration, then the nervous [symptoma.com] Acute Cystitis A complicated UTI occurs in a person with an abnormal urinary tract or an increased susceptibility to infection. [doi.org] (Predisposing Factors) The following are the risk factors associated with Acute Infective Cystitis: The risk increases as one ages; older individuals are generally more susceptible [dovemed.com] Alterations in Host Defense Mechanisms Obstruction – Key factor in increasing susceptibility to UTI but does not necessarily predispose to infection. [auanet.org] Agammaglobulinemia Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion. [ncbi.nlm.nih.gov] An increased susceptibility to infection is the clinical hallmark of the disorder. [clinicaladvisor.com] The clinical picture was dominated by severe episodes of recurrent upper respiratory tract infections. [ncbi.nlm.nih.gov] Bacterial Vaginosis BV has been associated with a wide array of health issues, including preterm births, pelvic inflammatory disease, increased susceptibility to HIV infection, and other chronic [ncbi.nlm.nih.gov] BACKGROUND: Bacterial vaginosis (BV) is the most common cause of vaginitis among women worldwide and is associated with increased susceptibility to sexually transmitted infections [ncbi.nlm.nih.gov] Although BV can go away on its own, treatment is important because having BV can increase your susceptibility to: HIV infection Herpes Simplex Virus (HSV) Chlamydia Gonorrhea [plannedparenthood.org] Cystitis Use of Diaphragm for Contraception: Use of any contraceptive implants are considered foreign bodies, and it makes the body of an individual more susceptible to infections. [medlife.com] It becomes less resilient and may struggle more to keep infection at bay. Diabetes Certain medical conditions can increase susceptibility to developing cystitis. [avogel.co.uk] Post-radiation or Chemotherapy Radiation and chemotherapy weaken the immune system of the body and increase the risk of infections. [medlife.com] Malnutrition Increased susceptibility to infections. Delayed and prolonged healing of even small wounds and cuts. Irritability and dizziness Skin and hair becomes dry. [news-medical.net] […] of adverse nutritional status and increased susceptibility to infection. [doi.org] Malnutrition and Infection Malnutrition increases risk of infection PEM is a common cause of secondary immune deficiency and susceptibility to infection in humans ( Table [doi.org] Cold Exposure This results in tissue damage, reduced function and increased susceptibility to infections. [healthand.com] RCE increased survival of infection by entomopathogenic fungi in both the chill-susceptible D. melanogaster ( Le Bourg et al., 2009 ) and freeze-tolerant P. isabella ( Marshall [jeb.biologists.org] Atrophic Vaginitis […] painful sexual intercourse bleeding after intercourse[7] painful urination[3] blood in the urine increased urinary frequency[3][6] incontinence increased susceptibility to [en.wikipedia.org] In case of urinary system atrophy, there will be incontinence, increased susceptibility to urinary infections, and burning micturition. [gleneaglesglobalhospitals.com] A lack of estrogen increases the pH value, rendering the body susceptible to vaginal/urinary infections. It also thins the vaginal walls, making it inelastic and dry. [dovemed.com] Adenovirus Infection Increasingly potent immunosuppressive agents have reduced the incidence of rejection of transplanted organs while increasing patient susceptibility to opportunistic infections [ncbi.nlm.nih.gov] Both TSA and MG-132 pretreatments could increase the CAR expression in the two cell lines, but the drug pretreatments could only make A549 cells more susceptible to adenovirus [ncbi.nlm.nih.gov] infectivity. [ncbi.nlm.nih.gov] Skin Infection We hypothesized that the absence or reduction of the filaggrin protein could compromise skin barrier and increase patients' susceptibility to recurrent skin infection. [ncbi.nlm.nih.gov] OBJECTIVE: To identify baseline patient characteristics associated with increased susceptibility to surgical site infection (SSI) after elective surgery. [ncbi.nlm.nih.gov] CONCLUSION: This study highlights a novel association between FLG-null mutations and an increased susceptibility to recurrent bacterial skin infection among patients with [ncbi.nlm.nih.gov]
