Increased Susceptibility to Infections: Causes & Reasons

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Possible Causes for Increased Susceptibility to Infections

Lethal Ataxia with Deafness and Optic Atrophy

susceptibility to infections / recurrent infections - Intellectual deficit / mental / psychomotor retardation / learning disability - Nerve conduction abnormality - Optic [csbg.cnb.csic.es]

Levels of uric acid in blood were normal in all these four affected males, and none of them presented with increased susceptibility to infections. [doi.org]

Frequent infections Frequent, severe infections Increased frequency of infection infections, recurrent Predisposition to infections Susceptibility to infection [ more ] 0002719 [rarediseases.info.nih.gov]

Adrenal Cushing Syndrome

An increased susceptibility to infection may also lead to sepsis. Hyperglycemia and hypertension are a common association as it was there in this case. [ijem.in]

Increased susceptibility to infections. Affected children tend to be obese but grow slowly so are short for their age. How does Cushing's syndrome progress? [patient.info]

susceptibility to some infections including pneumonia and TB. [nadf.us]

Shwachman Syndrome

Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections. [rarediseases.org]

These may include increased tooth decay (dental caries), mouth ulcers, and/or disease of the tissues that surround and support the teeth (periodontal disease). [rarediseases.org]

Primary Immune Deficiency Disorder

The most common symptom of PIDD is an increased susceptibility to infection. [symptoma.com]

Abstract: Patients with primary immunodeficiency diseases most often are recognized because of their increased susceptibility to infection (chronic or recurrent infections [asmscience.org]

susceptibility to infection. [lls.org]

Complement Factor D Deficiency

[…] by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway. [malacards.org]

Properdin deficiency is also associated with increased susceptibility to infection with Neisseria organisms. [clinicaladvisor.com]

Disorders of the complement cascade may or may not result in increased susceptibility to infections. [antimicrobe.org]

Complement Deficiency Syndrome

C3 27 Bacterial infections, SLE-like syndrome C4 26 SLE-like syndrome, encapsulated bacterial infections C1-INH 2-10:100,000 Angioedema MBL 2-7% UK population Increased susceptibility [sinobiological.com]

There are more than 150 PID diseases, and PID leads to increased susceptibility to infection. Most of the PIDs present with only B-cell defects (Fig 1). [pedsinreview.aappublications.org]

Complement deficiency or dysfunction may increase susceptibility to infection and seems to be related to certain autoimmune disorders. [doctor-clinic.org]

Properdin Deficiency

Deficiency of properdin is a rare X-linked condition characterized by increased susceptibility to infection with Neisseria meningitidis associated with a high mortality rate [ncbi.nlm.nih.gov]

Most individuals have had either an increased susceptibility to infection, rheumatic disorders, or angioedema. [ommbid.mhmedical.com]

[…] in complement leads to increased susceptibility to infection? [quizlet.com]

Immunodeficiency due to Ficolin 3 Deficiency

Some patients may show increased susceptibility to infection in the perinatal or neonatal period, whereas others may show autoimmune features as adults. [diseaseinfosearch.org]

Decreased MBL levels may be associated with increased susceptibility to infections when the adaptive immune system is immature (in early childhood) 12 or has been suppressed [labcorp.com]

[…] the overall susceptibility of an individual to infectious disease and predisposes to greater severity when infections occur. [labcorp.com]

Papillon Lefevre Disease

Other symptoms of PLS may include pyogenic skin infections, nail dystrophy, hyperhidrosis, increased susceptibility to infection, and ectopic cranial calcifications (Laass [genedx.com]

The disease is characterized by palmoplantar hyperkeratosis, loss of deciduous and permanent teeth and increased susceptibility to infections. [ncbi.nlm.nih.gov]

The exact mechanism of the increased susceptibility to infections is also unknown, but some investigators have demonstrated a dysfunction in neutrophil motility and bactericidal [jiaomr.in]

Complement 3 Deficiency

susceptibility to infections. [quizlet.com]

Among the possible complications are the following: Deficiencies of the terminal complement components increases susceptibility to infections by Neisseria. [en.wikipedia.org]

This may lead to an increased susceptibility to infection and a balance must often be struck between controlling immune complex disease and increasing propensity to infection [patient.info]

Agammaglobulinemia

Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion. [ncbi.nlm.nih.gov]

An increased susceptibility to infection is the clinical hallmark of the disorder. [clinicaladvisor.com]

The clinical picture was dominated by severe episodes of recurrent upper respiratory tract infections. [ncbi.nlm.nih.gov]

Female with more than three X Chromosomes

Immunoglobulin anomalies and an increased susceptibility to infection have also been reported. Cardiovascular malformations may also be present. [orpha.net]

Autosomal Agammaglobulinemia

An increased susceptibility to infection is the clinical hallmark of the disorder. [dermatologyadvisor.com]

Primary immunodeficiency diseases are inherited disorders of the immune system that result in an increased susceptibility to infection and an increased morbidity and mortality [mhmedical.com]

susceptibility to infection. [hamad.qa]

Combined Immunodeficiency due to CD3-Gamma Deficiency

Combined Immunodeficiency Diseases Genetic defects in T-cell function lead to an increased susceptibility to infections or to other clinical problems that are more serious [musculoskeletalkey.com]

Recently a new syndrome has been described, designated "Mendelian Susceptibility to Mycobacterial Infection"(MIM 209950) in which patients present increased susceptibility [jped.com.br]

Disorders of complement system Complement abnormalities also lead to increased susceptibility to infections. [microbiologybook.org]

Chédiak-Higashi Syndrome

The Chediak-Higashi syndrome (CHS) is a rare form of partial albinism which includes increased susceptibility to infections, a hemorrhagic tendency and peripheral polyneuropathies [deepblue.lib.umich.edu]

susceptibility to infection [ 2, 3 ]. [link.springer.com]

Patients exhibit partial oculocutaneous albinism, increased susceptibility to infections and the presence of giant granules in leukocytes. [scielo.br]

Familial Nasal Polyposis

susceptibility to infections. [en.wikipedia.org]

[…] in the nose or throat), slow wound healing, eye problems such as glaucoma or cataracts, weakened immune system (immunodeficiency) which causes an increased susceptibility [en.wikipedia.org]

[…] to infections and adrenal insufficiency. [en.wikipedia.org]

Radiation Sickness Syndrome

Radioactive elements such as uranium and barium, release excess energy in the form of particles or waves. Alpha particles, beta particles, and gamma rays are types of radioactive emissions that can cause damage by interacting with the atoms that make up living cells. All types of radiation can cause damage to the[…] [msdmanuals.com]

Hyper-IgM Syndrome Type 3

As a consequence, people with HIGM have an increased susceptibility to infections. [owlapps.net]

As a consequence, people with HIGM have an increased susceptibility to infections.[9][7][10] Signs and symptoms[edit] Hyper IgM syndrome can have the following syndromes:[ [en.wikipedia.org]

X-Linked Properdin Deficiency

The deficiency of this protein leads to an increased susceptibility to bacterial infections caused by Neisseria, among other genera. [oa.upm.es]

Hyper-IgM Syndrome Type 5

As a consequence, people with HIGM have an increased susceptibility to infections.[9][7][10] Signs and symptoms[edit] Hyper IgM syndrome can have the following syndromes:[ [en.wikipedia.org]

Hyper-IgM Syndrome Type 4

As a consequence, people with HIGM have an increased susceptibility to infections.[9][7][10] Signs and symptoms[edit] Hyper IgM syndrome can have the following syndromes:[ [en.wikipedia.org]

Mannose-Binding Lectin Deficiency

On the whole, our findings indicate an association between MBL deficiency and increased susceptibility to infections. [ncbi.nlm.nih.gov]

susceptibility to infections. [ncbi.nlm.nih.gov]

Abstract Mannose-binding lectin (MBL) deficiency due to variations in the MBL gene is associated with increased susceptibility to infections. [ncbi.nlm.nih.gov]

C1q Deficiency

Abstract: Patients with primary immunodeficiency diseases most often are recognized because of their increased susceptibility to infection (chronic or recurrent infections [asmscience.org]

These patients have increased susceptibility to infections with encapsulated microorganisms. [mayomedicallaboratories.com]

This may lead to an increased susceptibility to infection and a balance must often be struck between controlling immune complex disease and increasing propensity to infection [patient.info]

Rhinovirus Infection

These results may also help explain the increased susceptibility of children to rhinovirus infections. [atsjournals.org]

His research focuses upon factors that increase susceptibility to virus infection in asthma, COPD, Cystic Fibrosis and bronchiectasis. [elsevier.com]

It is equally as important for researchers to investigate whether SARS-CoV-2 potentially increases a person’s susceptibility to other infections. [degruyter.com]

Tetrasomy X

An increased susceptibility to infections during childhood has also been reported. [orpha.net]

Fetal Nicotine Spectrum Disorder

Respiratory infections also increase demands for medical interventions in terms of outpatient services and hospital administrations. [ehp.niehs.nih.gov]

The results of this study are of relevance to public health policy, as children with higher risk of respiratory infections may be more susceptible to environmental hazards [ehp.niehs.nih.gov]

Respiratory Infection

Contrary to what people may think, other factors, such as becoming chilled, wet, or tired, do not cause colds or increase a child's susceptibility to infection. [msdmanuals.com]

Immunodeficiency due to a C5 to C9 Complement Component Deficiency

These patients have increased susceptibility to infections with encapsulated microorganisms. [pediatric.testcatalog.org]

This may lead to an increased susceptibility to infection and a balance must often be struck between controlling immune complex disease and increasing propensity to infection [patient.info]

Primary complement deficiencies are closely associated with increased susceptibility to infection, rheumatic/autoimmune diseases, or angioedema. [adc.bmj.com]

Lymphopenic Agammaglobulinemia - Short-Limbed Dwarfism Syndrome

Primary immunodeficiency diseases are inherited disorders of the immune system that result in an increased susceptibility to infection and an increased morbidity and mortality [mhmedical.com]

SELECTIVE IMMUNOGLOBULIN DEFICIENCIES  Reported in 1% of all patients with recurrent infection  Isolated Ig A deficiency reported in 0.2% of normal population  Increased [slideshare.net]

Symptoms include oculocutaneous (eye-related) albinism, and increased susceptibility to pyogenic infections (Fundenberg, 1980). [web2.uwindsor.ca]

Iatrogenic Cushing Syndrome

Increased susceptibility to infections. Liver swelling with increased liver enzymes ALP, ALKP. Calcinosis Cutis a condition of calcium deposits in the skin. [secondchanceaihadogs.com]

An increased susceptibility to infection may also lead to sepsis. Hyperglycemia and hypertension are a common association as it was there in this case. [ijem.in]

[…] urination Visual problems caused by glaucoma or cataracts Increased susceptibility to infections Thin, fragile skin that bruises easily and heals slowly Pinkish streaks that [labtestsonline.org]