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135 Possible Causes for Increased Susceptibility to Infections, Malabsorption Syndrome, Recurrent Otitis Media

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] We describe a case of flucytosine malabsorption in a pediatric patient with Shwachman syndrome, a rare disease in the pediatric age group characterized by pancreatic insufficiency[ncbi.nlm.nih.gov] otitis media, mastoiditis, and two episodes of pneumonia.[journals.plos.org]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] In 4 patients (7%), the first clinical manifestation of CVID was damage to the gastrointestinal tract (enterocolitis and malabsorption syndrome).[f1000research.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Past medical history may also reveal secondary causes of hypogammaglobulinemia, such as nephrotic syndrome, malabsorption/gastroenteropathy (e.g., intestinal lymphangiectasia[online.epocrates.com] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • HIV Infection

    Fig 3. eSF enhance HIV infection more potently than DCs in a manner involving both trans -infection and increased susceptibility of T cells to HIV infection.[journals.plos.org] They may present with recurrent infections of the respiratory tract, including otitis media, tonsillitis, sinusitis, pharyngitis, and bronchitis.[symptoma.com] HIV infection increases susceptibility to smoking-induced emphysema. Chest. 2000;117(5 suppl 1):285S. 33. Kirk GD, Merlo C, O'Driscoll P, et al.[aafp.org]

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] , and symptoms of irritable bowel syndrome also occur in children who have common variable immunodeficiency. 8 Causative organisms for infection include Clostridium difficile[aafp.org] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org]

  • Cartilage Hair Hypoplasia

    CONCLUSIONS: Humoral immunity is impaired in CHH and contributes to the increased susceptibility to infections.[ncbi.nlm.nih.gov] The main findings are "celiac syndrome" with diarrhea and failure to thrive.[ncbi.nlm.nih.gov] Here, we present a case of CHH with mild skeletal changes and immunological findings associated with recurrent otitis media, neutropenia, and lymphopenia.[ncbi.nlm.nih.gov]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[ncbi.nlm.nih.gov] Table 1 Presenting features of classical and atypical severe combined immunodeficiency and Omenn syndrome Fig. 1 Chest radiograph from a 5-month-old infant with severe combined[doi.org] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[medbullets.com]

  • Kabuki Syndrome

    In particular, most KS patients show increased susceptibility to infections and have reduced serum immunoglobulin levels, while some suffer also from autoimmune manifestations[ncbi.nlm.nih.gov] […] food (malabsorption).[rarediseases.org] otitis media.[ncbi.nlm.nih.gov]

  • Acquired Immunodeficiency Syndrome

    […] microliter or less than 14% of total lymphocytes, and increased susceptibility to opportunistic infections and malignant neoplasms.[hon.ch] Clinical syndromes might vary by infecting species. Enterocytozoon bieneusi is associated with malabsorption, diarrhea, and cholangitis.[cdc.gov] […] respiratory infections (sinusitis, tonsillitis, otitis media, and pharyngitis) Herpes zoster Angular cheilitis Recurrent oral ulceration Papular pruritic eruptions Seborrheic[web.archive.org]

  • Giardiasis

    Although B cell dysfunction has traditionally been thought to increase both susceptibility to infection with Giardia and the rate of treatment failure [ 22 ], more recent[doi.org] Steatorrhea is a common finding in patients who have malabsorption syndrome. 3.2.[intechopen.com] Recurrent bacterial infections, such as otitis media, chronic sinusitis and recurrent pneumonia due to diminished immunoglobulin (Ig) levels and impaired antibody production[ncbi.nlm.nih.gov]

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