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288 Possible Causes for Increased Susceptibility to Infections, Meningitis, Recurrent Otitis Media

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[] Signs and symptoms of primary immunodeficiency can include: Frequent and recurrent pneumonia, bronchitis, sinus infections, ear infections, meningitis or skin infections Inflammation[] As a result, patients have increased rates of severe health complications, including infections such as pneumonias, cellulitis, meningitis, deep soft tissue abscesses, and[]

  • Acute Otitis Media

    This increased susceptibility is likely due to the younger infant and child’s shorter eustachian tube, its horizontal position, their limited exposure to both bacterial and[] Meningitis in a patient with a cochlear implant is not necessarily related to the implant.[] This study evaluated the quality of life in children with recurrent acute otitis media aged less than 24 months.[]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[] Common infections include: bronchitis ear infections meningitis pneumonia sinus infections skin infections Some of these infections can be serious.[] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[]

  • Otitis Media

    Whilst this is often accompanied by a feeling of relief as the pressure inside the ear is released, this can lead to excessive draining of the ear and increases susceptibility[] The patient presented petrositis and bilateral laryngeal paralysis with lymphocytic meningitis after six and eight months respectively.[] Recurrent otitis media:Patients with recurrent otitis media may be placed on daily doses of an antibiotic such as sulfisoxazole or amoxicillin prophylaxis for 3 to 6 months[]

  • Bacterial Otitis Media

    . 68 The association of certain genetic polymorphisms in TNFA, IL6, IL10, and TLR4 (toll-like receptor 4) genotypes with increased susceptibility for otitis media 68 - 70[] The possibility of BM should be borne in mind in patients with otitis media presenting with persistent meningeal symptoms.[] Eleven patients (35%) had a recurrent episode of acute bacterial otitis media during the follow-up period.[]

  • Recurrent Neisseria Infections due to Factor D Deficiency

    […] by increased susceptibility to bacterial infections, particularly Neisseria infections, due to a defect in the alternative complement pathway.[] Meningitis The term meningitis refers to inflammation the meninges of the brain or spinaL cord.[] Immunology 36; 863-867 Schejbel et al 2009 Properdin Deficiency in recurrent otitis media and pneumonia.[]

  • Common Variable Immunodeficiency

    susceptibility to infections.[] […] to the meningeal compartment.[] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[]

  • Agammaglobulinemia

    Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion.[] Tabs Content Clinical Overview Diagnosis Indications for Testing Recurrent infections in males during infancy or early childhood Respiratory tract (lungs, ears, sinuses) Meningitis[] ., in addition to giardiasis) are typical for agammaglobulinemia patients, and recurrent otitis media is described in the vast majority of cases.[]

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[] […] confused with CNS injury, may be differentiated by CNS imaging studies, such as computed tomography, magnetic resonance imaging, and ultrasound, to separate densities of the meningeal[] otitis media, mastoiditis, and two episodes of pneumonia.[]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[] A 35-day-old female with severe combined immunodeficiency developed cytomegalovirus (CMV) meningitis before undergoing hematopoietic stem cell transplantation.[] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[]

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