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282 Possible Causes for Increased Susceptibility to Infections, Pediatric Disorder, Recurrent Otitis Media

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] Loading metrics Figures Citation: Church JA (2006) A Pediatric Genetic Disorder Diagnosed in Adulthood. PLoS Med 3(1): e15.[journals.plos.org] […] infections (otitis media), and skin infections.[ghr.nlm.nih.gov]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] Common variable immunodeficiency disorders in children: delayed diagnosis despite typical clinical presentation. J Pediatr. 2009; 154(6): 888-94. PubMed Wilmott RW.[arupconsult.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Sensorineural hearing loss in primary antibody deficiency disorders. J Pediatr. 2008 Aug. 153(2):293-6. [Medline].[emedicine.com] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Congenital Neutropenia

    Congenital neutropenia is characterized by a decrease in the absolute number of circulating neutrophils and an increased susceptibility to infections.[ncbi.nlm.nih.gov] Falk PM, Rich K, Feig S, Stiehm ER, Golde DW, Cline MJ (1977) Evaluation of congenital neutropenic disorders by in vitro bone marrow culture.[link.springer.com] Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis[ncbi.nlm.nih.gov]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[ncbi.nlm.nih.gov] Severe combined immunodeficiency disorders represent pediatric emergencies due to absence of adaptive immune responses to infections.[ncbi.nlm.nih.gov] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[medbullets.com]

  • Mucopolysaccharidosis 2

    Until two decades ago, HSCT had high mortality rates because of (1) the preconditioning regimen prior to HSCT, which caused severe side effects including increased susceptibility[ncbi.nlm.nih.gov] Abstract Mucopolysaccharidosis type II (MPSII) is an inherited disorder due to a deficiency of the lysosomal enzyme iduronate-2-sulfatase (IDS).[ncbi.nlm.nih.gov] otitis media Broad chest Ivory-colored papular skin lesions on the upper back and sides of the upper arms Protuberant abdomen Diarrhea Short stature Skeletal deformities[symptoma.com]

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] "Immunodeficiency Disorders". 1993, Pediatrics in Review, 14: 226-236. Meischl , C., Roos, D.[wellpath.uniovi.es] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org]

  • Mucopolysaccharidosis 1

    Increased susceptibility to respiratory tract infections.[patient.info] ., The mucopolysaccharidoses: a heterogeneous group of disorders with variable pediatric presentations. J Pediatr, 2004. 144(5 Suppl): p. S27-34. 2). Beesley, C.E., D.[egl-eurofins.com] Typical clinical findings at various ages include: 0 - 6 months Chronic rhinitis Recurrent otitis media or "glue ear" with thick cerumen Umbilical or inguinal hernia Above[medicalhomeportal.org]

  • Down Syndrome

    Leukemia, thyroid diseases, autoimmune disorders, epilepsy, intestinal obstruction, and increased susceptibility to infections (including recurrent respiratory infections)[emedicine.com] Author information 1 Specialized Medical Center, Department of Pediatric Respiratory Medicine, Sleep Disorders Center, Box 84350, Riyadh 11671, Saudi Arabia.[ncbi.nlm.nih.gov] Christensen, An Instructive Case of Transient Myeloproliferative Disorder, Clinical Pediatrics, 10.1177/0009922816662460, 56, 3, (288-289), (2016).[doi.org]

  • Alpha-Mannosidosis

    Dental anomalies (diastema), large ears, macroglossia, joint stiffness,, hepatosplenomegaly, enlarged head circumference, hearing loss (sensorineural), increased susceptibility[disorders.eyes.arizona.edu] Disorders E-2903 168 Measurement of Health Outcomes in Pediatric Neurologic Disorders E-2910 169 The Influence of Computer Resources on Child Neurology E-2918 170 Education[books.google.es] […] infections, especially upper airway infections, pulmonary infections and acute/serous otitis media infections.[en.wikipedia.org]

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