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192 Possible Causes for Increased Susceptibility to Infections, Pulmonary Fibrosis, Recurrent Otitis Media

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Croft PR, Racz MI, Bloch JD, Palmer CH: Autopsy confirmation of severe pulmonary interstitial fibrosis secondary to Munchausen syndrome presenting as cystic fibrosis.[aacijournal.biomedcentral.com] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Granulomatosis with Polyangiitis

    susceptibility to infection cystitis (bladder inflammation) easily broken bones diabetes cognitive changes such as mood swings sterility cancer of the bladder.[betterhealth.vic.gov.au] People with GPA were more likely to have a diagnosis of pulmonary fibrosis (OR 5.7, 95% CI: 1.7, 19.5; P 0.01) and sinus infections (OR 2.7, 95% CI: 1.8, 4.2; P 0.0001) recorded[ncbi.nlm.nih.gov] otitis media otalgia lower respiratory symptoms hemoptysis renal symptoms hematuria skin leukocytoclastic angiitis Imaging Radiography indication should be performed in all[medbullets.com]

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] fibrosis and/or bone marrow failure, telomere-related, Dyskeratosis congenita AD 42 73 TERT Aplastic anemia, Pulmonary fibrosis and/or bone marrow failure, telomere-related[blueprintgenetics.com] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org]

  • Gastroesophageal Reflux Disease

    Conclusions Severe hypochlorhydria generated by PPI use leads to bacterial colonisation and increased susceptibility to enteric bacterial infection.[dx.doi.org] In some patients seepage of acid into the lungs may lead to pneumonia, lung abscess, and interstitial pulmonary fibrosis.[news-medical.net] Conversely, no conclusive clinical evidence supports a link between gastroesophageal reflux and other supraesophageal problems, including otalgia, recurrent otitis media,[emedicine.medscape.com]

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] […] function tests, testicular fibrosis, dental problems, diabetes mellitus and pubertal delays.[dashforacure.org] otitis media, mastoiditis, and two episodes of pneumonia.[journals.plos.org]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] Four patients had a complete resolution of pulmonary infiltration. 18 (50%) patients with sarcoidosis had new signs indicating pulmonary fibrosis progression (p 0.16).[erj.ersjournals.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Otitis Media

    Whilst this is often accompanied by a feeling of relief as the pressure inside the ear is released, this can lead to excessive draining of the ear and increases susceptibility[news-medical.net] RSV was identified early as a pathogen that appeared to create long-term pulmonary complications, primarily asthma, in as many as half of infants with bronchiolitis.[web.archive.org] Recurrent otitis media:Patients with recurrent otitis media may be placed on daily doses of an antibiotic such as sulfisoxazole or amoxicillin prophylaxis for 3 to 6 months[symptoma.com]

  • Acute Otitis Media

    This increased susceptibility is likely due to the younger infant and child’s shorter eustachian tube, its horizontal position, their limited exposure to both bacterial and[coreem.net] RSV was identified early as a pathogen that appeared to create long-term pulmonary complications, primarily asthma, in as many as half of infants with bronchiolitis.[emedicine.medscape.com] This study evaluated the quality of life in children with recurrent acute otitis media aged less than 24 months.[ncbi.nlm.nih.gov]

  • Immunodeficiency due to Ficolin 3 Deficiency

    Some patients may show increased susceptibility to infection in the perinatal or neonatal period, whereas others may show autoimmune features as adults.[diseaseinfosearch.org] A NEJM report describes a man with repeated severe bacterial pulmonary infections, bronchiectasis, pulmonary fibrosis, warts, and a cerebral abscess.[allergynotes.blogspot.com] otitis media Recurrent bronchitis Decreased proportion of CD8-positive T cells Tonsillitis Recurrent viral infections Cyclic neutropenia Abnormality of bone marrow cell morphology[mendelian.co]

  • Congenital Neutropenia

    Congenital neutropenia is characterized by a decrease in the absolute number of circulating neutrophils and an increased susceptibility to infections.[ncbi.nlm.nih.gov] Often confused with cystic fibrosis, these patients do not typically demonstrate abnormal pulmonary findings.[neutropenia.ca] Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis[ncbi.nlm.nih.gov]

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