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257 Possible Causes for Increased Susceptibility to Infections, Recurrent Otitis Media, Recurrent Pneumonia

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] Important signs that may indicate a PIDD include: • Recurrent, unusual or difficult to treat infections • Poor growth or loss of weight • Recurrent pneumonia, ear infections[aaaai.org] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] We present an intriguing case of a 69-year-old man presenting with recurrent pneumonia caused by a rare organism Staphylococcus lugdunensis, eventually determined to be caused[ncbi.nlm.nih.gov] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Gastroesophageal Reflux Disease

    Conclusions Severe hypochlorhydria generated by PPI use leads to bacterial colonisation and increased susceptibility to enteric bacterial infection.[dx.doi.org] Some of these atypical symptoms may include: Laryngitis-Chronic Cough-Hoarseness or Voice Disturbances Bronchitis and/or Asthma Recurrent Pneumonia Sleep Apnea Acid erosion[stretta-therapy.com] Conversely, no conclusive clinical evidence supports a link between gastroesophageal reflux and other supraesophageal problems, including otalgia, recurrent otitis media,[emedicine.medscape.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] pneumonia, chronic sinusitis, and intestinal giardiasis were studied.[jci.org] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Congenital Neutropenia

    Congenital neutropenia is characterized by a decrease in the absolute number of circulating neutrophils and an increased susceptibility to infections.[ncbi.nlm.nih.gov] Untreated patients may suffer from chronic gingivitis, oral ulcers, skin abscesses, recurrent pneumonia, or septicemia [1].[file.scirp.org] Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis[ncbi.nlm.nih.gov]

  • Severe Combined Immunodeficiency

    Primary immunodeficiencies (PIDs) represent a large group of disorders with an increased susceptibility to infections.[ncbi.nlm.nih.gov] Without a functional immune system, SCID patients are susceptible to recurrent infections such as pneumonia, meningitis and chicken pox, and can die before the first year[ncbi.nlm.nih.gov] He has also experienced recurrent episodes of otitis media from repeat Streptoccous pneumoniae. He notably has reduced T and B cell counts.[medbullets.com]

  • Granulomatosis with Polyangiitis

    susceptibility to infection cystitis (bladder inflammation) easily broken bones diabetes cognitive changes such as mood swings sterility cancer of the bladder.[betterhealth.vic.gov.au] otitis media otalgia lower respiratory symptoms hemoptysis renal symptoms hematuria skin leukocytoclastic angiitis Imaging Radiography indication should be performed in all[medbullets.com] There were no signs of recurrent otitis media or mastoiditis, and sigmoid sinus thrombosis was ruled out.[thieme-connect.com]

  • Nephrotic Syndrome

    […] plt aggregation), low complement, hyperlipidemia (increased hepatic synthesis of lipoprotein), increased susceptibility to infections (loss of IgG).[errolozdalga.com] The side effects of these drugs include increased susceptibility to infection, hair loss and decreased blood cell production.[kidney.org] susceptibility to new infection or reactivation of latent infections Suppression of the hypothalamic-pituitary-axis (HPA) may occur following prolonged therapy with the potential[actharnephrology.com]

  • Mucopolysaccharidosis 2

    Until two decades ago, HSCT had high mortality rates because of (1) the preconditioning regimen prior to HSCT, which caused severe side effects including increased susceptibility[ncbi.nlm.nih.gov] Clinical manifestations include dyspnea, difficulties with clearing secretions, cough, wheezing, and recurrent bronchitis or pneumonia.[karger.com] otitis media Broad chest Ivory-colored papular skin lesions on the upper back and sides of the upper arms Protuberant abdomen Diarrhea Short stature Skeletal deformities[symptoma.com]

  • Primary Ciliary Dyskinesia

    Asthma is associated with increased susceptibility to infection. Minerva Med (2015) 106:1–7. PubMed Abstract Google Scholar 44.[journal.frontiersin.org] Primary ciliary dyskinesia (PCD) is an inherited disorder manifested in children as chronic otomastoiditis, recurrent pneumonia, and chronic sinusitis.[ncbi.nlm.nih.gov] Seven cases were complicated with recurrent otitis media and 15 cases were complicated with infertility.[ncbi.nlm.nih.gov]

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