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301 Possible Causes for Increased Susceptibility to Infections, Recurrent Otitis Media, Sinusitis

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] Scarred tympanic membranes or chronic perforation due to recurrent otitis media is commonly seen in patients with antibody deficiencies.[worldallergy.org] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] As with other antibody deficiencies, the most common types of recurrent infections involve the ears, sinuses, nose, bronchi and lungs.[aaaai.org] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Gastroesophageal Reflux Disease

    Conclusions Severe hypochlorhydria generated by PPI use leads to bacterial colonisation and increased susceptibility to enteric bacterial infection.[dx.doi.org] Symptom assessments, neuropsychiatric evaluations, fiberoptic laryngoscopy, pulmonary function tests, allergic skin prick tests, radiographs of the chest and sinuses, esophageal[ncbi.nlm.nih.gov] Conversely, no conclusive clinical evidence supports a link between gastroesophageal reflux and other supraesophageal problems, including otalgia, recurrent otitis media,[emedicine.medscape.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Infections of the lungs (pneumonia), ear (otitis) and sinuses (sinusitis) are most frequently reported.[symptoma.com] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Granulomatosis with Polyangiitis

    susceptibility to infection cystitis (bladder inflammation) easily broken bones diabetes cognitive changes such as mood swings sterility cancer of the bladder.[betterhealth.vic.gov.au] CT of the sinuses showed severe mucosal thickening.[ncbi.nlm.nih.gov] otitis media otalgia lower respiratory symptoms hemoptysis renal symptoms hematuria skin leukocytoclastic angiitis Imaging Radiography indication should be performed in all[medbullets.com]

  • Congenital Neutropenia

    Congenital neutropenia is characterized by a decrease in the absolute number of circulating neutrophils and an increased susceptibility to infections.[ncbi.nlm.nih.gov] Most of the infections occur in the mouth, throat, sinuses, lungs, and skin. Painful mouth ulcers, gum infections, ear infections, and periodontal disease are common.[seattlecca.org] Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis[ncbi.nlm.nih.gov]

  • Congenital Acquired Immune Deficiency Syndrome

    KEY TERMS Agammaglobulinemia —The lack of gamma globulins in the blood, associated with an increased susceptibility to infection.[healthofchildren.com] […] hepatomegaly, splenomegaly, lymphadenopathy ( 2 sites involved or bilateral involvement of one site), parotitis, recurrent or persistent upper respiratory tract infection, sinusitis[symptoma.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Primary Ciliary Dyskinesia

    Asthma is associated with increased susceptibility to infection. Minerva Med (2015) 106:1–7. PubMed Abstract Google Scholar 44.[journal.frontiersin.org] This supports our hypothesis of a bacterial reservoir in the sinuses.[ncbi.nlm.nih.gov] Seven cases were complicated with recurrent otitis media and 15 cases were complicated with infertility.[ncbi.nlm.nih.gov]

  • Upper Respiratory Infection

    […] to infection.[ncbi.nlm.nih.gov] […] data suggest that previous history of acute sinusitis influences the composition of the NP microbiota, characterized by a depletion in relative abundance of specific taxa[ncbi.nlm.nih.gov] RESULTS: Two hundred and three infants, aged 3 months-3 years with upper respiratory tract infection over 36 h and a history of recurrent acute otitis media were included[ncbi.nlm.nih.gov]

  • Agammaglobulinemia

    Neither increased susceptibility to infections nor agammaglobulinemia have been described as a manifestation of terminal 14q32.33 deletion.[ncbi.nlm.nih.gov] Diagnostic methods A diagnosis of XLA should be considered in patients with recurrent or persistent otitis media, pneumonia, sinusitis, and conjunctivitis starting before[orpha.net] ., in addition to giardiasis) are typical for agammaglobulinemia patients, and recurrent otitis media is described in the vast majority of cases.[symptoma.com]

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