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277 Possible Causes for Increased Susceptibility to Infections, Recurrent Otitis Media, Thrombocytopenia

  • Primary Immune Deficiency Disorder

    The most common symptom of PIDD is an increased susceptibility to infection.[symptoma.com] In other patients – adults as well as children and infants – weight loss, chronic gastrointestinal infections, and autoimmune disease such as immune thrombocytopenia, hemolytic[mountsinai.org] […] association with CVID. [30] Autoimmune phenomena As many as 20% of patients with CVID develop autoimmune complications. [1] Rheumatoid arthritis , vitiligo , hemolytic anemia , thrombocytopenia[emedicine.medscape.com]

  • Shwachman Syndrome

    Affected individuals with neutropenia may also have additional abnormalities believed to result from an increased susceptibility to infections.[rarediseases.org] Neutropenia was the most common hematologic abnormality (88%), but leukopenia, thrombocytopenia, and anemia were also frequently encountered.[ncbi.nlm.nih.gov] otitis media, mastoiditis, and two episodes of pneumonia.[journals.plos.org]

  • Common Variable Immunodeficiency

    susceptibility to infections.[ncbi.nlm.nih.gov] Thrombocytopenia was only found in this cluster (36% of cases, manifested as Immune Thrombocytopenia (ITP) or Evans syndrome).[ncbi.nlm.nih.gov] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • HIV Infection

    Fig 3. eSF enhance HIV infection more potently than DCs in a manner involving both trans -infection and increased susceptibility of T cells to HIV infection.[journals.plos.org] As part of the work up for thrombocytopenia, a rapid HIV antibody based assay was done and was negative.[ncbi.nlm.nih.gov] They may present with recurrent infections of the respiratory tract, including otitis media, tonsillitis, sinusitis, pharyngitis, and bronchitis.[symptoma.com]

  • Congenital Acquired Immune Deficiency Syndrome

    KEY TERMS Agammaglobulinemia —The lack of gamma globulins in the blood, associated with an increased susceptibility to infection.[healthofchildren.com] Hepatitis Nephropathy Persistent fever lasting more than one month Neutropenia ( 1,000/µL), thrombocytopenia ( 100,000/µL) or anemia ( 8 g/dL).[symptoma.com] Antibody immunodeficiencies are marked by hypo- or dysgammaglobulinemia, recurrent bacterial otitis media, and sinopulmonary infections.[medical-dictionary.thefreedictionary.com]

  • Congenital Neutropenia

    Congenital neutropenia is characterized by a decrease in the absolute number of circulating neutrophils and an increased susceptibility to infections.[ncbi.nlm.nih.gov] […] the Congenital Neutropenia Panel ICD-10 Disease D82.0 Wiskott-Aldrich syndrome D70.9 Congenital neutropenia D70.9 Cyclic neutropenia D70.9 Kostmann syndrome D69.4 X-linked thrombocytopenia[blueprintgenetics.com] Herein, we describe two siblings with SCN born from consanguineous parents who were referred for complaints of recurrent cutaneous infections, gingivitis, purulent otitis[ncbi.nlm.nih.gov]

  • Wiskott Aldrich Syndrome

    Wiskott-Aldrich syndrome (WAS) is an X-linked recessive disorder characterized by thrombocytopenia, small platelets, eczema, increased susceptibility to infection, and immunodeficiency[ncbi.nlm.nih.gov] […] other symptomatic thrombocytopenia, infectious complications, and autoimmunity.[ncbi.nlm.nih.gov] otitis media infections.[emedicine.medscape.com]

  • Gastroesophageal Reflux Disease

    Conclusions Severe hypochlorhydria generated by PPI use leads to bacterial colonisation and increased susceptibility to enteric bacterial infection.[dx.doi.org] Enzyme replacement therapy and chemical chaperone therapy were successful for the skin disorders, joint contractures, hepatosplenomegaly and thrombocytopenia, but he also[ncbi.nlm.nih.gov] Conversely, no conclusive clinical evidence supports a link between gastroesophageal reflux and other supraesophageal problems, including otalgia, recurrent otitis media,[emedicine.medscape.com]

  • Hypogammaglobulinemia

    susceptibility to pyogenic infections.[medical-dictionary.thefreedictionary.com] Treatment advances in posttransplant lymphoproliferative disease Evaluation of thrombocytopenia in the acute coronary syndrome Hb Baden structural and functional characterization[books.google.com] Case description: A 41-year-old female with TS, hypothyroidism, and recurrent otitis media as a child presents with severe vitamin deficiencies including: iron, vitamin B12[eposters.net]

  • Otitis Media

    Whilst this is often accompanied by a feeling of relief as the pressure inside the ear is released, this can lead to excessive draining of the ear and increases susceptibility[news-medical.net] Two studies reported potential haematological complications (e.g. leukopenia, neutropenia, anaemia and thrombocytopenia) ( Giebink 1990 ; Principi 1989 ); these occurred in[doi.org] Recurrent otitis media:Patients with recurrent otitis media may be placed on daily doses of an antibiotic such as sulfisoxazole or amoxicillin prophylaxis for 3 to 6 months[symptoma.com]

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