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85 Possible Causes for Indifference to Pain, Self Mutilation

  • Channelopathy-Associated Congenital Insensitivity to Pain

    There is no support group for congenital insensitivity/indifference to pain.[] Since affected individuals do not respond appropriately to painful situations, they engage in self-mutilating behavior such as biting of the oral mucosa and fingers and sustain[] […] to pain congenital pain indifference indifference to pain, congenital, autosomal recessive pain insensitivity, congenital SOURCE: Emory University - Department of Human Genetics[]

  • Lesch Nyhan Syndrome

    This syndrome is characterized clinically by mental retardation, chorea, athetosis, hyperuricemia, uricosuria and self-mutilation.[] Self-mutilative behavior is a hallmark of the disease. Hyperuricemia leads to hyperuricuria and uric acid nephrolithiasis.[] This report describes a 10-year-old male child with confirmed LNS who was treated for self-mutilation of his hands, tongue, and lips with repeated botulinum toxin A (BTX-A[]

  • Familial Dysautonomia

    This results in feeding difficulties, excessive sweating, absence of tears, indifference to pain, reduced corneal sensitivity, emotional lability and red blotching of the[] Oro-dental features include a lack of tongue fungiform papillae, impairment of taste, oro-dental self-mutilation, dental crowding, excessive plaque and calculus accumulation[] They include dental trauma; dental and soft tissue self-mutilation; normal dental age; normal sequence and timing of eruption and exfoliation of teeth; smaller tooth size;[]

  • Autosomal Dominant Hereditary Sensory and Autonomic Neuropathy

    […] to Pain, Congenital, Autosomal Recessive Asymbolia For Pain Congenital Analgesia, Autosomal Recessive Insensitivity To Pain, Channelopathy-Associated Neuropathy, Hereditary[] Keywords: Genetic, Neuropathy, Pain, Self-mutilation.[] We only considered patients with HSANs II, IV, and V, or related variants associated with profound pain hyposensitivity (or “pain indifference”).[]

  • Hereditary Sensory Neuropathy

    Other features include reduced or absent tears, depressed deep tendon reflexes, absent corneal reflex, postural hypotension and relative indifference to pain.[] None had trophic limb changes, evidence of weakness, or a tendency to self-mutilation and each had normal motor studies on neurophysiological testing.[] This syndrome is therefore denoted congenital indifference to pain ( 2 ).[]

  • Congenital Autosomal Dominant Indifference to Pain

    Magee KR, Schneider SF, Rosenzweig N: Congenital indifference to pain. J Nerv Ment Dis 1961;132:249–259. Schneider SF: A psychological basis for indifference to pain.[] They also noticed self- mutilating behavior like biting of his tongue, chewing his fingers, bruising, and manipulation the wounds.[] More Symptoms of Indifference to pain, congenital, autosomal recessive » • • • Back to: « Indifference to pain Genetics of Indifference to pain, congenital, autosomal recessive[]

  • Neuropathy

    Landrieu P et al . (1990) Dominantly transmitted congenital indifference to pain . Ann Neurol 27 : 574–578 26.[] mutilation (65%) Aspiration pneumonia Self mutilation (88%) Delayed development Breech presentation (37%) Hypothermia Delayed development Unique features No axon flare No[] McDonough, Global Nav1.7 Knockout Mice Recapitulate the Phenotype of Human Congenital Indifference to Pain, PLoS ONE, 10.1371/journal.pone.0105895, 9, 9, (e105895), (2014)[]

  • Hereditary Sensory and Autonomic Neuropathy Type 1C

    Indifference to pain syndrome in a twelve-year-old boy (case report). Tehran Univ Med J 2007; 65 (4) :87-91.[] Then, it was decided to give bite guard to prevent self-mutilated trauma to the tongue.[] We only considered patients with HSANs II, IV, and V, or related variants associated with profound pain hyposensitivity (or “pain indifference”).[]

  • Dysautonomia

    The features of familial dysautonomia include lack of tears, emotional lability, relative indifference to pain, increased sweating, cold hands and feet, red blotching of the[] […] blotching with eating, excitement, or sleeping, excessive sweatin (especially on the head) Psychiatric: poor attention span, anxiety, depression, auditory processing problems, self-mutilation[] There is self-mutilation, which can also cause ulcers, skin or tissue loss, as well as short nails.[]

  • Hysterical Neurosis

    , nonanatomical sensory loss, split of midline by pain or vibratory stimulation, changing boundaries of hypalgesia, giveaway weakness) were sought in 30 consecutive neurology[] The question items with high independent coefficients were manipulation (0.4416), intolerance of aloneness (0.3797), demanding nature (0.3768), self-mutilation (0.3609), visual[] Anxiety Disorder Dysthymia Simple Phobia Obsessive Compulsive Disorder Major Depression Borderline Personality Disorder Childhood emotional/sexual abuse Physical Neglect Self-mutilated[]

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