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65 Possible Causes for Indurated Skin Lesion, Subcutaneous Mass

  • Skin Cancer

    SCC’s are often superficial, discrete, and hard lesions arising from an indurated, rounded, and elevated base ( Alam and Ratner, 2001 ) ( Table 2 ).[ncbi.nlm.nih.gov] […] arising from indurated, rounded, elevated base Sore that will not heal(bleeding or developing a crust) Anatomic distribution Sun exposed areas (head and neck, hands) Skin[ncbi.nlm.nih.gov] […] infections, scarring Chronic scarring/inflammation from burns, leg ulcers, radiation, lupus, immunosuppression, human papillomavirus Typical clinical presentation Superficial lesion[ncbi.nlm.nih.gov]

  • Squamous Cell Carcinoma of the Skin

    A 72-year-old male patient was receiving second-line chemotherapy for metastatic squamous cell carcinoma of the skin (SCCS) when he was diagnosed with concurrent metastatic melanoma (BRAF mutant). Chemotherapy was ceased and he was treated with 4 cycles of ipilimumab immunotherapy. The patient experienced[…][ncbi.nlm.nih.gov]

  • Calcinosis Circumscripta

    A 2.5-y-old, male common marmoset ( Callithrix jacchus jacchus ) developed a 2-cm, interscapular, subcutaneous mass with variably firm and cystic areas.[ingentaconnect.com] Intralesional injections of triamcinolone acetonide are effective in treating indurated and disfiguring skin lesions.[the-medical-dictionary.com] It consists of numerous large, subcutaneous, calcified masses that may be associated with papular and nodular skin lesions of calcinosis.[dermaamin.com]

  • Rheumatoid Nodule

    The MRI appearance of a subcutaneous rheumatoid nodule is that of a nonspecific ill-defined mass with long T1- and long T2-relaxation times.[ncbi.nlm.nih.gov] We describe a 69-year-old woman with RA who presented initially with fever and an indurated skin lesion on the right thigh.[ncbi.nlm.nih.gov] ; may be painful Subcutaneous lesions develop at sites of trauma or at pressure points May involve abdominal wall and heart Clinical images Images hosted on other servers:[pathologyoutlines.com]

  • Tuberculosis

    Osseous destruction and, possibly, air within subcutaneous tissues may be identified radiographically, or the empyema may present as a palpable soft-tissue mass.[emedicine.com]

  • Cutaneous Metastasis in Breast Cancer

    The lesions were painless, non-pruritic. The skin around the nodules was firm and indurated on palpation.[ccij-online.org] lesions with indurations of the skin (‘‘en cuirasse’’ metastatic carcinoma), telangiectatic papulovesicles, purpuric plaques mimicking vasculitis, and alopecia aerate-like[intechopen.com] The facial lesions were larger, harder, skin colored, and some lesions were covered with necrotic slough while some of them were ulcerated.[ccij-online.org]

  • Calcinosis Universalis

    , painful masses in neck Progresses down back over shoulders, chest, abdomen Rounded or linear calcification starting in neck More clumplike in places than calcinosis universalis[learningradiology.com] It consists of numerous large, subcutaneous, calcified masses of that may be associated with papular and nodular skin lesions of calcinosis.[webmedcentral.com] […] of GI tract, lung, ovary , breast, kidney May resemble myositis ossificans progressiva Myositis ossificans progressive (fibrodyplasia ossificans progressiva) Begins with subcutaneous[learningradiology.com]

  • Chromoblastomycosis

    Clinical picture Mycetoma is characterized by a triad of painless ‎subcutaneous mass, multiple sinuses and discharge ‎containing grains.[who.int] Several weeks or months later, new lesions, projecting 1 to 2 mm above the skin, may appear along paths of lymphatic drainage.[msdmanuals.com] masses.[mycology.adelaide.edu.au]

  • Carcinoma

    This tumor presents clinically as a solitary lesion with a cystic component located in the subcutaneous layer abutting the skin.[ncbi.nlm.nih.gov] The patient received radiation therapy to the pelvic mass but in January 2015 was found to have new peritoneal and lymph-node metastases (Panel A, red arrows), as well as[nejm.org] On ultrasound, it appears as a circumscribed complex cystic and solid mass abutting the dermis. The occurrence of PH in the breast is very rare.[ncbi.nlm.nih.gov]

  • Onchocerciasis

    Human infection is caused by O. volvulus, with heavy infestations usually being characterized by subcutaneous nodules (onchocercomas) containing tangled masses of adult worms[medical-dictionary.thefreedictionary.com] […] and itching skin lesions located on the limbs and positive anti-filarial antibodies in serum ( Klin Padiatr 2006;218:41 ) 53 year old man presented with a 4 month history[pathologyoutlines.com] Usually, nodules are close to each other and form large masses with small satellite nodules. This gives a lobulated feel to the tumor.[emedicine.medscape.com]

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