Infiltration: Causes & Reasons

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Possible Causes for Infiltration

Mycosis Fungoides

Brain biopsy demonstrated massive eosinophilic infiltrates but no MF cells. Despite treatment, new lesions developed and the patient died. [ncbi.nlm.nih.gov]

Eosinophilic cellulitis, or Wells syndrome, is a rare inflammatory dermatitis that involves a dermal infiltrate of eosinophils. [ncbi.nlm.nih.gov]

Several cases of unusual lichenoid reaction characterized by a mixed lichenoid inflammatory infiltrate with prominent infiltration of the papillary dermis and epidermis by [ncbi.nlm.nih.gov]

Paget Disease of the Breast

An erythematous patch in mammary Paget disease is usually sharply demarcated and infiltrated (unlike eczematous dermatitis). [web.archive.org]

The mechanism by which large neoplastic cells of glandular origin (ie, the Paget cells) infiltrate and spread to the overlying epidermal layers of the nipple and adjacent [emedicine.medscape.com]

Malignant epithelial (Paget) cells infiltrate and proliferate in the epidermis, causing thickening of the nipple and the areolar skin. [web.archive.org]

Autoimmune Gastritis

We believe that it should be regarded as a single disease "infiltrative sclerosing cholangitis" because this is not a primary disease and sarcoidosis would be responsible [ncbi.nlm.nih.gov]

During the acute/deterioration phase, autoreactive and cytotoxic effector cells leave blood vessels to infiltrate the target site through a multi-step mechanism involving [ncbi.nlm.nih.gov]

infiltration [mean 34.5/high power field (HPF), >30 eosinophils/HPF in 46.1%] and neutrophil infiltration (44.2%). [ncbi.nlm.nih.gov]

Endometrial Stromal Sarcoma

Endometrial stromal sarcoma (ESS) rarely infiltrates the great vessels. [ncbi.nlm.nih.gov]

Microscopically, the tumor lacked infiltrative features, conforming to the definition of ESN. [ncbi.nlm.nih.gov]

There are three grades for endometrial stromal tumors, as follows.[1] It was previously known as endolymphatic stromal myosis because of diffuse infiltration of myometrial [en.wikipedia.org]

Adenocarcinoma of the Breast

(C50._) Infiltrating duct and mucinous carcinoma (C50._) Infiltrating duct and tubular carcinoma (C50._) Infiltrating duct and colloid carcinoma (C50._) 8524/3 Infiltrating [training.seer.cancer.gov]

stage 2 Infiltrating ductal carcinoma of breast, stage 3 Infiltrating ductal carcinoma of breast, stage 4 Infiltrating ductal carcinoma of left female breast Infiltrating [icd9data.com]

When the tumor infiltrates the skin, ulceration may be present. [pathologyatlas.ro]

Lingular Pneumonia

Pulmonary infiltrates are associated with pneumonia, tuberculosis, and nocardiosis.[citation needed] Pulmonary infiltrates can be observed on a chest radiograph. [en.wikipedia.org]

There is no way to know that something is an infiltrate. [doctorslounge.com]

These substances are called infiltrates. [livestrong.com]

Endometriosis

There is considerable involvement of the bowel and bladder with deeply infiltrative endometriosis [1-3]. [ncbi.nlm.nih.gov]

Transvaginal ultrasound has been shown to be an accurate and reliable diagnostic tool in detecting ovarian endometrioma and deep infiltrating endometriosis. [dx.doi.org]

To describe a multidisciplinary approach for the resection of deeply infiltrative endometriosis using the robotic platform. [ncbi.nlm.nih.gov]

Hashimoto Thyroiditis

Thyroidectomy demonstrated a PTC, HT with multiple lymphoepithelial cysts, and extensive multifocal infiltrates of eosinophils, generally confined to the cyst walls. [ncbi.nlm.nih.gov]

In our study, the CRTH2 expression on thyroid-infiltrating lymphocytes as well as on lymphocytes from peripheral blood was increased in HT as compared to controls. [ncbi.nlm.nih.gov]

In a peripheral area of 0.7 cm × 0.5 cm, a prominent lymphocytic infiltrate surrounding thyroid follicles was identifiable. [ncbi.nlm.nih.gov]

Keratitis

Dramatic improvement was observed at the sites of catarrhal infiltration without recurrence of infectious keratitis. [ncbi.nlm.nih.gov]

Examination revealed a paracentral large stromal infiltrate with a central 2-mm perforation. [bmcophthalmol.biomedcentral.com]

However, newly developed diffuse haziness with surrounding granular infiltration in the central cornea was noted. [ncbi.nlm.nih.gov]

Malignant Neoplasm of the Breast

Infiltrating ductal carcinoma is the most commonly diagnosed breast tumor, found in about 75% of cases and infiltrating lobular, infiltrating medullary, colloid, comedo or [symptoma.com]

stage 2 Infiltrating ductal carcinoma of breast, stage 3 Infiltrating ductal carcinoma of breast, stage 4 Infiltrating ductal carcinoma of left female breast Infiltrating [icd9data.com]

Carcinoma (M8010/3) - see also Neoplasm, by site, malignant duct (cell) (M8500/3) infiltrating (M8500/3) unspecified site 174.9 infiltrating duct (M8500/3) unspecified site [healthprovidersdata.com]

Acute Interstitial Nephritis

Acute interstitial nephritis (AIN) is common, but prominent eosinophil infiltration in patients with acute interstitial nephritis is rare. [ncbi.nlm.nih.gov]

This is the first case describing predominance of neutrophilic infiltration in AIN associated with Sjögren syndrome. [ncbi.nlm.nih.gov]

In both patients, minor salivary glands and bone marrow were infiltrated by lymphocytes, consistent with B-cell activation induced by HIV-1 infection. [ncbi.nlm.nih.gov]

Undifferentiated Carcinoma of Liver and Intrahepatic Biliary Tract

Cholangiocarcinoma that infiltrated a Periampullary Duodenal Diverticula and the head of the pancreas. [gastrointestinalatlas.com]

Periductal infiltrating Periductal infiltrating intrahepatic tumors are most common at the hilum (comprise over 70% of hilar-perihilar cholangiocarcinomas), where they are [radiopaedia.org]

Around the tumor cell nests, dense lymphoplasmacytic infiltration was observed, and infiltrative lymphocytes and plasma cells were of mature appearance and without atypia [wjgnet.com]

Astrocytoma

[…] astrocytoma, and rarely infiltrating gliomas. [ncbi.nlm.nih.gov]

Materials and Methods Fifteen patients with infiltrative astrocytomas were recruited into this prospective multicenter study between July 2014 and December 2016. [ncbi.nlm.nih.gov]

AUTHORS' DISCLOSURES OF POTENTIAL CONFLICTS OF INTEREST Diffuse Infiltrating Oligodendroglioma and Astrocytoma The following represents disclosure information provided by [ascopubs.org]

Cronkhite-Canada Syndrome

Duodenal polyp with edema und inflammatory stroma infiltration (b). [bmcgastroenterol.biomedcentral.com]

Most polyps showed cystically dilated glands without dysplasia or edematous stroma with inflammatory cell infiltration. [ncbi.nlm.nih.gov]

The microscopic findings of rectal polyps showed hamartomatous polyps having smooth muscle fibers from muscularis mucosa and chronic inflammatory cell infiltration without [kjim.org]

Nosocomial Pneumonia

Many conditions other than nosocomial pneumonia mimic pulmonary infiltrates (eg, fluid, atelectasis) on chest radiographs. [emedicine.medscape.com]

= 0 point Diffuse or patchy infiltrate = 1 point Localized infiltrate= 2 points Pulmonary radiography No infiltrate = 0 point Diffuse or patchy infiltrate = 1 point Localized [antimicrobe.org]

HSV-1 pneumonitis develops in intubated patients who have unchanging or persistent pulmonary infiltrates after 2 weeks of antimicrobial therapy. [emedicine.medscape.com]

Carcinoma of the Breast

RESULTS: Kaplan-Meier survival analysis showed (a) for all patients that high tumor-infiltrating CD8+ and CD20+ B lymphocytes, low tumor-infiltrating FOXP3+ regulatory T cells [ncbi.nlm.nih.gov]

Keywords breast cancer breast carcinoma infiltrating ductal carcinoma infiltrating lobular carcinoma invasive ductal carcinoma of the breast invasive lobular carcinoma of [breast-cancer-research.biomedcentral.com]

When the tumor infiltrates the skin, ulceration may be present. [pathologyatlas.ro]

Linitis Plastica

Abstract A review of 2369 cases of resected primary colorectal carcinoma identified 15 cases of diffusely infiltrating colorectal carcinoma. [ncbi.nlm.nih.gov]

The diagnosis of diffuse-type gastric cancer, named linitis plastica (LP), is difficult because of its infiltration into the submucosa. [ncbi.nlm.nih.gov]

Microscopically, the tumor is an anaplastic adenocarcinoma of a diffusely infiltrating type with a variable amount of scirrhous reaction. [pubs.rsna.org]

Eosinophilic Gastroenteritis

Eosinophilic infiltration of the stomach and bowel. [ncbi.nlm.nih.gov]

Eosinophilic infiltrates of the gastrointestinal tract. [dx.doi.org]

Gastric submucosal granuloma with eosinophilic infiltration. [ncbi.nlm.nih.gov]

Fibrillary Astrocytoma

Factors predicting progression of low-grade diffusely infiltrating astrocytoma. [neurologyindia.com]

The World Health Organization brain tumor classification scale is: I – benign and circumscribed, II – benign and infiltrative, III – cellular anaplasia, and IV – malignant [advancedradteaching.com]

This revealed a diffuse infiltrating astrocytic tumour without higher malignancy - a fibrillary astrocytoma, WHO grade II. [eurorad.org]

Eosinophilic Gastritis

Subsequent histological examination showed a non-malignant transmural eosinophilic infiltration of the stomach wall, a rare pathological entity. [ncbi.nlm.nih.gov]

INFLAMMATORY CHANGES with eosinophilic infiltration of the walls of the gastrointestinal tract may occur in two forms. [jamanetwork.com]

[…] gastric eosinophilic inflammation; gastric eosinophilic infiltration; gastric eosinophilia Definition : Excessive infiltration by eosinophilic leukocytes. [humpath.com]

Lymphocytic Gastritis

Intraepithelial lymphocytes in small bowel and stomach were positive for the antibody MT-1, indicating a T-cell infiltrate at both sites. [ncbi.nlm.nih.gov]

The intestinal lymphocytic infiltrate was not monoclonal, and gene rearrangements were not detected. [ncbi.nlm.nih.gov]

A, Dense inflammatory infiltrate and edema in lamina propria (H&E). [giejournal.org]

IgG4-Related Retroperitoneal Fibrosis

Immunohistochemical staining for IgG4 did not demonstrate infiltration of IgG4-positive plasma cells in the retroperitoneal mass, but revealed significant infiltration of [ncbi.nlm.nih.gov]

Again, these infiltrates were not characterized further. [em-consulte.com]

Immunoglobulin G4 (IgG4)-related sclerosing disease is a newly recognized clinicopathological entity characterized by lymphoplasmacytic infiltration and varying degrees of [ncbi.nlm.nih.gov]

Kimura Disease

The choline/creatine levels of subcutaneous and infiltrative parotid lesions were slightly higher than those of normal parotid glands. [ncbi.nlm.nih.gov]

Excisional biopsy revealed hyperplasia of lymphoid follicles, and infiltration with lymphocytes and eosinophils around lacrimal gland acini, leading to the pathological diagnosis [ncbi.nlm.nih.gov]

Histopathologic examination confirmed significant thickening of the vascular wall, constriction of the vessel lumen, and infiltration of numerous eosinophils and lymphocytes [ncbi.nlm.nih.gov]

Cryptogenic Organizing Pneumonia

[…] with extensive progressive infiltrates. [caridokumen.com]

Also the infiltrations found in chest X-ray and computed tomography responded well and showed remarkable resolution tendency quickly. [ncbi.nlm.nih.gov]

The Masson's bodies showed collagenization with lymphocytic infiltration. Hyalinization of Masson's bodies with little inflammatory infiltration was frequently seen. [ncbi.nlm.nih.gov]

Paget Disease of the Nipple

An underlying intraductal or infiltrating duct carcinoma of the breast was present in each case. [ncbi.nlm.nih.gov]

An erythematous patch in mammary Paget disease is usually sharply demarcated and infiltrated (unlike eczematous dermatitis). [web.archive.org]

The mechanism by which large neoplastic cells of glandular origin (ie, the Paget cells) infiltrate and spread to the overlying epidermal layers of the nipple and adjacent [emedicine.medscape.com]

Malignant Angioendotheliomatosis

An 84-year-old man was examined for progressive pain, edema, and infiltrating skin lesions on his lower extremities. [ncbi.nlm.nih.gov]

The absence of pulmonary infiltrates precluded any lung biopsy. [ncbi.nlm.nih.gov]

An autopsy demonstrated the characteristic intravascular and focal perivascular infiltrate of malignant angioendotheliomatosis (MAE) throughout the body but concentrated in [ncbi.nlm.nih.gov]

Acute Interstitial Pneumonitis

ILDs are also referred to as: – Diffuse parenchymal lung diseases – Pulmonary fibrosis – Chronic infiltrative lung diseases The differential diagnosis of ILDs is quite lengthy [clinicaladvisor.com]

Another HRCT scan was made because of worsening of symptoms and this showed rapidly progressive infiltrates in most lobes. [ncbi.nlm.nih.gov]

We treated the patient with pulse steroid therapy, and improvement in respiratory function and decreased pulmonary infiltrations demonstrated good response to steroids use [ncbi.nlm.nih.gov]

Desquamative Interstitial Pneumonia

There was a significantly greater extent of interstitial fibrosis (P = 0.02), lymphoid follicles (P < 0.001) and eosinophilic infiltration (P < 0.0001) in patients with DIP [ncbi.nlm.nih.gov]

The alveolar walls are usually mildly thickened by fibrous tissue and infiltrated by a moderate number of lymphocytes. [ncbi.nlm.nih.gov]

Desquamative interstitial pneumonia is chronic lung inflammation characterized by mononuclear cell infiltration of the airspaces; it occurs almost exclusively in current or [msdmanuals.com]

Unresolved Pneumonia

Within the first few days, persistence or even progression of infiltrates on chest radiographs is not unusual. [ncbi.nlm.nih.gov]

B-Symptoms and pulmonary infiltrate were improved immediately by a therapy with steroids. [ncbi.nlm.nih.gov]

Chest radiographs demonstrated a left lower-lobe infiltrate with left effusion (Figure 1). [mdmag.com]

Transient Sarcoidosis

However, as a rule, the infiltrate in sarcoidosis lies scattered throughout the dermis, whereas the infiltrate in lupus vulgaris is located close to the epidermis. [dermaamin.com]

Stage III - parenchymal infiltrates without hilar adenopathy. [patient.info]

For patients who do have impaired lung function with pulmonary infiltrates, adrenal corticosteroids are prescribed, often for an extended period of time. [medical-dictionary.thefreedictionary.com]