Infiltration: Causes & Reasons

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Possible Causes for Infiltration

Mycosis Fungoides

Several cases of unusual lichenoid reaction characterized by a mixed lichenoid inflammatory infiltrate with prominent infiltration of the papillary dermis and epidermis by [ncbi.nlm.nih.gov]

In these cases, the atypical lymphoid infiltrate is comprised predominately of CD4-positive lymphocytes. [ncbi.nlm.nih.gov]

In each, the biopsies showed an atypical folliculotropic lymphocytic infiltrate accompanied by follicular mucinosis in certain cases. [ncbi.nlm.nih.gov]

Esophagitis

EO, PPI-REE, and lymphocytic oesophagitis (LO) make up a group of disorders termed ‘infiltrative oesophagitis’, which is characterised by the infiltration of atypical cells [bjgp.org]

Eosinophilic esophagitis (EoE) is a unique form of non-IgE-mediated food allergy characterized by esophageal eosinophilic infiltration that commonly causes dysphagia and food [ncbi.nlm.nih.gov]

The black arrows indicate infiltration of eosinophils within the squamous cell layer of the luminal surface (H&E staining, original magnification ×200). [bjgp.org]

Keratitis

Dramatic improvement was observed at the sites of catarrhal infiltration without recurrence of infectious keratitis. [ncbi.nlm.nih.gov]

However, newly developed diffuse haziness with surrounding granular infiltration in the central cornea was noted. [ncbi.nlm.nih.gov]

The infiltrations were along the sutured corneal tear tracts. [ncbi.nlm.nih.gov]

Endometrial Stromal Sarcoma

Endometrial stromal sarcoma (ESS) rarely infiltrates the great vessels. [ncbi.nlm.nih.gov]

Microscopically, the tumor lacked infiltrative features, conforming to the definition of ESN. [ncbi.nlm.nih.gov]

There are three grades for endometrial stromal tumors, as follows.[1] It was previously known as endolymphatic stromal myosis because of diffuse infiltration of myometrial [en.wikipedia.org]

Paget Disease of the Breast

An erythematous patch in mammary Paget disease is usually sharply demarcated and infiltrated (unlike eczematous dermatitis). [web.archive.org]

The mechanism by which large neoplastic cells of glandular origin (ie, the Paget cells) infiltrate and spread to the overlying epidermal layers of the nipple and adjacent [emedicine.medscape.com]

Malignant epithelial (Paget) cells infiltrate and proliferate in the epidermis, causing thickening of the nipple and the areolar skin. [web.archive.org]

Hashimoto Thyroiditis

In a peripheral area of 0.7 cm × 0.5 cm, a prominent lymphocytic infiltrate surrounding thyroid follicles was identifiable. [ncbi.nlm.nih.gov]

A follicle infiltrated by lymphocytes. A group of slightly crowded epithelial cells in a follicular arrangement, infiltrated by lymphocytes. Note the nuclear streaking. [eurocytology.eu]

During the initial examination we observed infiltrative erythema of the forearm and muscle weakness and atrophy of the limbs. [ncbi.nlm.nih.gov]

Malignant Neoplasm of the Breast

Infiltrating ductal carcinoma is the most commonly diagnosed breast tumor, found in about 75% of cases and infiltrating lobular, infiltrating medullary, colloid, comedo or [symptoma.com]

stage 2 Infiltrating ductal carcinoma of breast, stage 3 Infiltrating ductal carcinoma of breast, stage 4 Infiltrating ductal carcinoma of left female breast Infiltrating [icd9data.com]

Carcinoma (M8010/3) - see also Neoplasm, by site, malignant duct (cell) (M8500/3) infiltrating (M8500/3) unspecified site 174.9 infiltrating duct (M8500/3) unspecified site [healthprovidersdata.com]

Endometriosis

Transvaginal ultrasound has been shown to be an accurate and reliable diagnostic tool in detecting ovarian endometrioma and deep infiltrating endometriosis. [dx.doi.org]

Robot-assisted laparoscopic partial cystectomy was performed for the deep-infiltrating bladder endometriosis. [ncbi.nlm.nih.gov]

A step‐by‐step guide to sonographic evaluation of deep infiltrating endometriosis First published: 04 June 2018 Cited by: 1 Funding: None. Conflict of interest: None. [dx.doi.org]

Autoimmune Gastritis

infiltration [mean 34.5/high power field (HPF), >30 eosinophils/HPF in 46.1%] and neutrophil infiltration (44.2%). [ncbi.nlm.nih.gov]

In all of these cases, the oxyntic mucosa showed lymphoplasmacytic infiltrates within the lamina propria with focal gland infiltration and damage. [ncbi.nlm.nih.gov]

The autoimmune gastritis had healed, and autoaggressive inflammatory infiltrates with focal destruction of corpus glands and hypertrophy of the parietal cells were no longer [ncbi.nlm.nih.gov]

Adenocarcinoma of the Breast

(C50._) Infiltrating duct and mucinous carcinoma (C50._) Infiltrating duct and tubular carcinoma (C50._) Infiltrating duct and colloid carcinoma (C50._) 8524/3 Infiltrating [training.seer.cancer.gov]

stage 2 Infiltrating ductal carcinoma of breast, stage 3 Infiltrating ductal carcinoma of breast, stage 4 Infiltrating ductal carcinoma of left female breast Infiltrating [icd9data.com]

When the tumor infiltrates the skin, ulceration may be present. [pathologyatlas.ro]

Paget Disease of the Nipple

An underlying intraductal or infiltrating duct carcinoma of the breast was present in each case. [ncbi.nlm.nih.gov]

An erythematous patch in mammary Paget disease is usually sharply demarcated and infiltrated (unlike eczematous dermatitis). [web.archive.org]

The mechanism by which large neoplastic cells of glandular origin (ie, the Paget cells) infiltrate and spread to the overlying epidermal layers of the nipple and adjacent [emedicine.medscape.com]

Acute Gastritis

Histopathological examination of antral biopsies revealed intense neutrophil infiltrates with microabscesses. [ncbi.nlm.nih.gov]

Mononuclear cells and neutrophils infiltrate the entire mucosa to the level of the muscularis, but exudate or crypt abscesses seldom result, as might be expected by such infiltration [web.archive.org]

In the antral mucosa there were edema, hyperemia, and intense polymorphonuclear leukocyte infiltration (neutrophils and some eosinophils) in the lamina propria, mucus layer [ncbi.nlm.nih.gov]

Carcinoma of the Breast

RESULTS: Kaplan-Meier survival analysis showed (a) for all patients that high tumor-infiltrating CD8+ and CD20+ B lymphocytes, low tumor-infiltrating FOXP3+ regulatory T cells [ncbi.nlm.nih.gov]

When the tumor infiltrates the skin, ulceration may be present. [pathologyatlas.ro]

[…] and fibroelastotic stroma Tubular Carcinoma Grade I Infiltrating Ductal Carcinoma, NOS Stellate infiltration Irregular infiltration 90% tubules May have >10% ribbons or cords [surgpathcriteria.stanford.edu]

Lingular Pneumonia

A chest CT showed not only an infiltrative shadow in the lingular division, but also a solid mass with calcification in the lingular bronchus. [ncbi.nlm.nih.gov]

Alveolar infiltration in the left lower lobe. From alveolar infiltration to lobar pneumonia. [mevis-research.de]

A chest computed tomography (CT) showed an infiltrative shadow in the lingular division. Two months later, a follow-up CT showed the shadow had remarkably improved. [ncbi.nlm.nih.gov]

Nosocomial Pneumonia

Many conditions other than nosocomial pneumonia mimic pulmonary infiltrates (eg, fluid, atelectasis) on chest radiographs. [emedicine.medscape.com]

= 0 point Diffuse or patchy infiltrate = 1 point Localized infiltrate= 2 points Pulmonary radiography No infiltrate = 0 point Diffuse or patchy infiltrate = 1 point Localized [antimicrobe.org]

HSV-1 pneumonitis develops in intubated patients who have unchanging or persistent pulmonary infiltrates after 2 weeks of antimicrobial therapy. [emedicine.medscape.com]

Epulis

The connective tissue was fat infiltrated (Figure 3b). Epithelium was hyperplastic (acanthosis) and partially ulcerated with deposition of a fibrinopurulent exudate. [ncbi.nlm.nih.gov]

When traumatized, the lesion contain inflammatory infiltrate and ulcerated area will be covered with fibrin and organisms from the oral flora.6 The fibrous epulis usually [ncbi.nlm.nih.gov]

(b) The histopathology of the lesion revealed highly collagenous matrix with moderate lymphoplasmacytic presence and fat infiltration (hematoxylin–eosin staining, original [ncbi.nlm.nih.gov]

Basal Cell Carcinoma

We discuss the differential diagnosis of the case, the difficulties in identifying infiltrative BCC, and the pathologic features of infiltrative BCC. [ncbi.nlm.nih.gov]

subgroup (10 nodular-infiltrative and 8 infiltrative subtypes). [ncbi.nlm.nih.gov]

CONCLUSIONS: Incomplete and close excision margins, infiltrative and micronodular subtypes and previous excision are strong risk factors for facial BCC recurrence. [ncbi.nlm.nih.gov]

Acute Respiratory Distress Syndrome

It is characterized by the acute onset of diffuse, bilateral pulmonary infiltrates secondary to noncardiogenic pulmonary edema, refractory hypoxia, and decreased lung compliance [ncbi.nlm.nih.gov]

Initially, the infiltrates may have a patchy peripheral distribution, but soon they progress to diffuse bilateral involvement with ground glass changes or frank alveolar infiltrates [emedicine.medscape.com]

Acute respiratory distress syndrome (ARDS) is a clinical syndrome of severe dyspnea of rapid onset, hypoxemia, and diffuse pulmonary infiltrates leading to respiratory failure [accessmedicine.mhmedical.com]

Cronkhite-Canada Syndrome

Most polyps showed cystically dilated glands without dysplasia or edematous stroma with inflammatory cell infiltration. [ncbi.nlm.nih.gov]

The microscopic findings of rectal polyps showed hamartomatous polyps having smooth muscle fibers from muscularis mucosa and chronic inflammatory cell infiltration without [kjim.org]

[…] surface epithelium.4) The microscopic findings in this case also showed many cystic dilatations of the glands; the largest one was filled with neutrophils and there was infiltration [kjim.org]

Colitis Cystica Profunda

Non-solid contents and a lack of infiltration can be visualized at transrectal US, which helps diagnose CCP. [ncbi.nlm.nih.gov]

[…] content, surrounded by variable degrees of fibrosis on a background of interspersed chronic inflammatory cells, with few colonic mucosal crypts and mild inflammatory cell infiltrate [acgcasereports.gi.org]

Biopsies showed inflammatory changes without tumor infiltration. [elsevier.es]

Acute Interstitial Nephritis

Most (78%) of cases had mononuclear cell infiltrates, no significant eosinophilic infiltrates were found, and glomeruli were not involved. [ncbi.nlm.nih.gov]

In both patients, minor salivary glands and bone marrow were infiltrated by lymphocytes, consistent with B-cell activation induced by HIV-1 infection. [ncbi.nlm.nih.gov]

Acute interstitial nephritis (AIN) is common, but prominent eosinophil infiltration in patients with acute interstitial nephritis is rare. [ncbi.nlm.nih.gov]

Extramammary Paget Disease

We report an unusual case of primary scrotal extramammary Paget disease that infiltrated reticular dermis and lymph vessels, with metastasis in inguinal lymph node. [ncbi.nlm.nih.gov]

In one of the biopsies, tumor cells were found in the dermis with an infiltrative growth pattern. [ncbi.nlm.nih.gov]

This case was initially misinterpreted as a metastatic gastric carcinoma to the vulva because an initial small, superficial biopsy specimen showed infiltration of signet ring [ncbi.nlm.nih.gov]

Carcinoma of the Male Breast

In our review, this is the first case of lobular in situ and infiltrating carcinoma of the male breast in a phenotypic and apparently genotypic male. [ncbi.nlm.nih.gov]

The intervening stroma was densely fibrotic, and the tumor infiltrated among tightly packed collagen bundles. [ncbi.nlm.nih.gov]

Infiltrating ductal carcinoma is the most common histology while lobular carcinoma represents less than 1% of all these tumors. [ncbi.nlm.nih.gov]

Astrocytoma

[…] astrocytoma, and rarely infiltrating gliomas. [ncbi.nlm.nih.gov]

Histologically, infiltrative astrocytomas have a spectrum of differentiation that is well-correlated to prognosis. [pathologystudent.com]

Materials and Methods Fifteen patients with infiltrative astrocytomas were recruited into this prospective multicenter study between July 2014 and December 2016. [ncbi.nlm.nih.gov]

Malignant Angioendotheliomatosis

An 84-year-old man was examined for progressive pain, edema, and infiltrating skin lesions on his lower extremities. [ncbi.nlm.nih.gov]

The absence of pulmonary infiltrates precluded any lung biopsy. [ncbi.nlm.nih.gov]

An autopsy demonstrated the characteristic intravascular and focal perivascular infiltrate of malignant angioendotheliomatosis (MAE) throughout the body but concentrated in [ncbi.nlm.nih.gov]

Uremic Pneumonitis

Figure 1Bilateral hemorrhagic infiltrates To cite this abstract: Fox C, Khalid H, Opole I. The Return of a “Forgotten Disease”: Uremic Pneumonitis. [shmabstracts.com]

In the acute phase there is vascular damage, congestion, oedema, and mononuclear cell infiltration; in the subacute phase the alveolar walls are infiltrated with mononuclear [kmle.co.kr]

The patient’s pulmonary symptoms and alveolar infiltrates completely resolved with repeated dialysis, consistent with the clinical picture of uremic pneumonitis (UP). [shmabstracts.com]

Unresolved Pneumonia

Within the first few days, persistence or even progression of infiltrates on chest radiographs is not unusual. [ncbi.nlm.nih.gov]

B-Symptoms and pulmonary infiltrate were improved immediately by a therapy with steroids. [ncbi.nlm.nih.gov]

Chest radiographs demonstrated a left lower-lobe infiltrate with left effusion (Figure 1). [mdmag.com]

Undifferentiated Carcinoma of Liver and Intrahepatic Biliary Tract

Cholangiocarcinoma that infiltrated a Periampullary Duodenal Diverticula and the head of the pancreas. [gastrointestinalatlas.com]

Periductal infiltrating Periductal infiltrating intrahepatic tumors are most common at the hilum (comprise over 70% of hilar-perihilar cholangiocarcinomas), where they are [radiopaedia.org]

Around the tumor cell nests, dense lymphoplasmacytic infiltration was observed, and infiltrative lymphocytes and plasma cells were of mature appearance and without atypia [wjgnet.com]

Cardiomyopathy

Adipositas cordis is a rare cardiomyopathy characterized by diffuse fatty infiltration of the ventricular myocardium or interventricular septum. [ncbi.nlm.nih.gov]

In 10.64% of cases, cardiac conduction was infiltrated by fibrosis, adipose, or both. [ncbi.nlm.nih.gov]

(Infiltrative Cardiomyopathy) By Thomas D. [msdmanuals.com]

Thyroid Lymphoma

Unfavorable prognosis is related to extracapsular extension, blood vessel wall infiltration, diffuse architectural pattern, and cervical lymph node involvement. [ncbi.nlm.nih.gov]

Ultrasonography revealed a circumscribed hypoechoic area bilaterally in each lobe of the thyroid, and fine-needle aspiration biopsy showed diffuse monotonous infiltration [ncbi.nlm.nih.gov]

Fine needle aspiration cytology of the neck mass demonstrated a large amount of lymphocyte infiltration. [ncbi.nlm.nih.gov]