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27 Possible Causes for Insomnia, Peripheral T Cells Decreased, Pertussis

  • Asthma

    Bordetella pertussis positive individuals had lower FEV 1 /FVC (77.1% v 80.7%, p   0.012) and more asthma symptoms than B pertussis negative cases.[dx.doi.org] Are you an adult who has asthma and insomnia?[nhlbi.nih.gov] RT‑qPCR demonstrated that VDR expression in the peripheral blood of asthmatic children was decreased.[ncbi.nlm.nih.gov]

  • Influenza

    OBJECTIVES: Influenza and pertussis vaccination programmes have been in place for pregnant women in the UK since 2009 and 2012, respectively.[ncbi.nlm.nih.gov] It is associated with a number of minor reversible CNS disturbances, including insomnia and reduced concentration, which are especially prominent in the elderly, and lowered[dx.doi.org] In contrast, IL-1R1 / mice showed a dramatic decrease in CD4 T-cell proliferation, suggesting that efficient T-helper cell priming in peripheral organs is dependent on a functional[dx.doi.org]

  • Graves Disease

    Berbers and Anne-Marie Buisman , Whole-cell or acellular pertussis vaccination in infancy determines IgG subclass profiles to DTaP booster vaccination , Vaccine , 36 , 2 ,[doi.org] Notably, HLA-DR14, a known risk factor for GD in Japanese individuals and the decreased regulatory T-cell numbers that were seen in the pediatric case, may affect the early[ncbi.nlm.nih.gov] The signs and symptoms of Graves' disease include insomnia, tremor, hyperactivity, hyperhidrosis, heat intolerance, weight loss despite increased appetite, diarrhea, frequent[symptoma.com]

  • Food Allergy

    Compared with infants who receive aP as their first pertussis vaccine, those who receive wP appear less likely to mount Th2 immune responses to either vaccine or extraneous[ncbi.nlm.nih.gov] (Hives) Angioedema Dermatitis Musculoskeletal Joint Pain Low Back Pain Auto – Immune Rheumatoid Arthritis Systemic Lupus Multiple Sclerosis Neurological Headache Fatigue Insomnia[foodallergy.com] This causes low FOXP3 mRNA levels and markedly decreased protein expression in peripheral blood lymphocytes of affected patients.[ncbi.nlm.nih.gov]

  • Essential Hypertension

    This splice variant may be responsible for the enhanced signal transduction via pertussis toxin–sensitive G proteins previously observed in lymphoblasts and fibroblasts from[doi.org] This study is evaluating three different behavioral interventions for treatment of insomnia and the effects of insomnia on blood pressure.[nhlbi.nih.gov] RESULTS: Compared with non-H-type hypertensive patients, CD4 T-cell percentage in peripheral blood was significantly decreased in H-type hypertensive patients.[ncbi.nlm.nih.gov]

  • Haddad Syndrome

    […] beclomethasone, fluticasone) Hyperimmune globulins (eg, varicella-zoster immune globulin) Immunizations (eg, vaccines, including diphtheria and tetanus toxoids [DT or Td], acellular pertussis[emedicine.medscape.com] The last cluster of symptoms is related to sleep disturbances, including: insomnia, nightmares and excessive dreaming.[psychopharmacologyinstitute.com] In contrast, immune cells in patients with TINU syndrome have a paradoxical suppression of cytokine production and a decrease in peripheral immune response, as demonstrated[uptodate.com]

  • Preterm Labor

    […] chloroquine, ChQ) reverses the rise in intracellular Ca 2 concentration ([Ca 2 ] i ) and cell shortening induced by uterotonics, and this reversal effect is inhibited by pertussis[ncbi.nlm.nih.gov] Sleep disorders If you’ve been diagnosed with insomnia, sleep apnea or another sleep disorder, you may be at an increased risk of having a preterm birth.[todaysparent.com] cells in peripheral blood was significantly decreased.[ncbi.nlm.nih.gov]

  • Alcoholic Liver Disease

    Immune AIDS and HIV Viral Hepatitis Infectious Disease Influenza Measles, Mumps, and Rubella Pneumonia Sexually Transmitted Diseases (STD) Chronic Sinusitis Whooping Cough or Pertussis[cdc.gov] […] unusually curved fingertips and nails (clubbed fingers) blotchy red palms significant weight loss weakness and muscle wasting confusion and memory problems, trouble sleeping (insomnia[nhs.uk] Peripheral Blood CD4 /CD25 Regulatory T Cells in Patients with Alcoholic Hepatitis, Alcoholism: Clinical and Experimental Research, 37, 8, (1361-1369), (2013).[doi.org]

  • Opsoclonus-Myoclonus Syndrome

    vaccines [1].[vaccinesafety.edu] Before DEX pulse therapy, frequency of T lymphocyte, in particular CD4-positive cell decreased markedly resulted in low CD4/8 ratio in the peripheral blood (PB).[ncbi.nlm.nih.gov] Behavioral and sleep disturbances, including extreme irritability, inconsolable crying, reduced and fragmented sleep (insomnia) and rage attacks are common.[rarediseases.org]

  • Multiple Sclerosis

    Philpott, The Inflammasome Pyrin Contributes to Pertussis Toxin-Induced IL-1β Synthesis, Neutrophil Intravascular Crawling and Autoimmune Encephalomyelitis, PLoS Pathogens[doi.org] Patients 18-75 years of age with a confirmed diagnosis of Multiple Sclerosis and Insomnia Disorder.[evergreenhealth.com] Immunologic changes included a marked decrease in proliferation of interferon γ–producing myelin-reactive CD4 T cells in peripheral blood and decreased titers of myelin-specific[dx.doi.org]

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