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69 Possible Causes for Insulin-like Growth Factor I Decreased

  • Growth Hormone Deficiency

    […] and growth factors, such as insulinlike growth factor‐I (IGF‐I), IGF‐II and their binding proteins (IGFBPs) [ 4 ].[] Growth hormone deficiency Growth hormone deficiency is classically defined as insufficient GH secretion that results in a decrease in the production of GH‐dependent hormones[]

  • Hepatocellular Carcinoma

    Hepatocellular carcinoma (HCC) can be difficult to diagnose and treat in patients with Osler-Rendu-Weber disease due to vascular malformation and regenerative nodular hyperplasia. In addition, percutaneous liver puncture should be avoided for the diagnosis and treatment as the procedure carries a high risk of[…][]

  • Woodhouse Sakati Syndrome

    Woodhouse-Sakati Syndrome (WSS) is a rare autosomal recessive multisystemic disorder that is marked by hypogonadism, alopecia, intellectual disability, deafness, diabetes mellitus and progressive extrapyramidal defects. Mutations in the gene C2orf37 are the cause of Woodhouse-Sakati syndrome. In the present study, a[…][]

  • Acute Alcohol Intoxication

    AAI produced in the adolescents of both sexes in our series: a decrease in growth hormone (GH) levels, without significant alteration of either insulin-like growth factor-I[] (IGF-I) or insulin-like growth factor binding protein-3 (IGFBP3); an increase in plasma glucose and a decrease in insulin in the female adolescents but not in the males.[]

  • Hypoglycemia

    […] levels of insulin-like growth factor (IGF)-I and IGFBP3 and the high expression of big IGF-II in the serum further confirmed the diagnosis of NICTH.[] , C-peptide, and growth hormone levels in the course of hypoglycemic episodes suggesting to the diagnosis of hypoglycemia induced by nonislet cell tumor, and the decreased[] […] glycosylated hemoglobin was normal and previous history of diabetes or use of oral hypoglycemic agents and insulin denied.The laboratory examination showed that the low level of insulin[]

  • Polycystic Ovary Syndrome

    Putatively, an elevated circulating concentration of insulin inhibits the production of insulin-like growth factor binding protein-1 (IGFBP-1), thus increasing the level of[] J Clin Invest 89 : 1006 – 1013 26 1994 Stimulation of low-density lipoprotein oxidation by insulin and insulin like growth factor I.[] […] free IGF-I in serum and stimulating ovarian androgen production.[]

  • Osteoporosis

    The correction of poor protein nutrition also improved serum prealbumin and insulin-like growth factor I concentrations and decreased the length of rehabilitation ( 59 ).[] Although little is known about insulin-like growth factor (IGF)-I and Ca metabolism during weight loss, reduced levels due to energy restriction ( 37 ) may decrease Ca absorption[]

  • Growth Failure

    At the same time, experimental studies indicate that those cytokines affect growth by interfering with the Growth Hormone (GH)/Insulin-like Growth Factor I (IGF-I) axis.[] Serum Insulin-Like Growth Factor (IGF-I) While children with severe congenital GHD usually can be diagnosed clinically at an early age based on typical clinical features shortly[] Moreover, IL-1β and TNF-α decrease murine bone growth in vitro by acting at the growth plate level.[]

  • Polyarthritis

    De Benedetti F, Alonzi T, Moretta A (1997) Interleukin 6 causes growth impairment in transgenic mice through a decrease in insulin-like growth factor-I: a model for stunted[]

  • Preeclampsia

    […] in the maternal-fetal glucose concentration gradient; thus, there is a decrease in glucose transport to the fetus, leading to IUGR. 13 Insulin-like growth factor-I (IGF-I[] […] and utilization of nutrients. 12 In preclinical trials, it has been shown that pancreatic agenesis of the fetus leads to fetal hyperglycemia and this results in secondary decrease[]

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