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120 Possible Causes for Insulin-like Growth Factor I Increased

  • Acromegaly

    Most cases of acromegaly are caused by pituitary adenomas, resulting in increased secretion of GH and insulin-like growth factor I subsequently.[symptoma.com] Physicians can also measure insulin-like growth factor I (IGF-I) levels, a protein which increase as growth hormone levels increase in people with suspected acromegaly.[empr.com] […] of increased levels of insulin-like growth factor-I (IGF-I).[orpha.net]

  • Acute Alcohol Intoxication

    (IGF-I) or insulin-like growth factor binding protein-3 (IGFBP3); an increase in plasma glucose and a decrease in insulin in the female adolescents but not in the males.[ncbi.nlm.nih.gov] The administration of alcohol had no effect on the serum levels of 25-hydroxycholecalciferol, 1,25-dihydroxycholecalciferol, calcitonin, or insulin-like growth factor I.[nejm.org] AAI produced in the adolescents of both sexes in our series: a decrease in growth hormone (GH) levels, without significant alteration of either insulin-like growth factor-I[ncbi.nlm.nih.gov]

  • Hypertension

    growth factor I 30 and leptin, 31 a neuropeptide that regulates appetite, have also been implicated in the pathogenesis of obesity-induced hypertension.[circ.ahajournals.org] Thus, although the mechanisms by which obesity and insulin resistance increase BP remain undefined, it is clear that these increases in BP are overlain on the inherited BP[circ.ahajournals.org] […] activity and sodium and water retention, and it could be that the hypertension is due to the lack of resistance to these secondary effects of insulin. 29 More recently, insulin-like[circ.ahajournals.org]

  • Essential Hypertension

    growth factor I 30 and leptin, 31 a neuropeptide that regulates appetite, have also been implicated in the pathogenesis of obesity-induced hypertension.[doi.org] Thus, although the mechanisms by which obesity and insulin resistance increase BP remain undefined, it is clear that these increases in BP are overlain on the inherited BP[doi.org] […] activity and sodium and water retention, and it could be that the hypertension is due to the lack of resistance to these secondary effects of insulin. 29 More recently, insulin-like[doi.org]

  • Acne Vulgaris

    Sadowski, Transdermal 17 beta-estradiol combined with oral progestogen increases plasma levels of insulin-like growth factor-I in postmenopausal women. J. Endocrinol.[doi.org] Development of hyperandrogenism during treatment with insulin-like growth factor-I (IGF-I) in female patients with Laron syndrome.[ncbi.nlm.nih.gov] Yen, Clomiphene citrate reduces serum insulin-like growth factor I and increases sex hormone-binding globulin levels in women with polycystic ovary syndrome. Fertil.[doi.org]

  • Obesity

    […] levels of endogenous hormones (sex steroids, insulin, and insulin-like growth factor I) associated with overweight and obesity and the contribution of abdominal obesity to[dx.doi.org] […] cancers of the colon, breast (in postmenopausal women), endometrium, kidney (renal-cell carcinoma), and esophagus (adenocarcinoma). 11 Potential biologic mechanisms include increased[dx.doi.org]

  • Arthritis

    Jiang J, Lichtler AC, Gronowicz GA, Adams DJ, Clark SH, et al. (2006) Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling.[doi.org]

  • Polycystic Ovary Syndrome

    Putatively, an elevated circulating concentration of insulin inhibits the production of insulin-like growth factor binding protein-1 (IGFBP-1), thus increasing the level of[ncbi.nlm.nih.gov] […] free IGF-I in serum and stimulating ovarian androgen production.[ncbi.nlm.nih.gov]

  • Osteoporosis

    The increased insulin-like growth factor I seen with higher protein intakes may increase osteoblast activity and promote mineralization of the bone matrix ( 34 ).[dx.doi.org] Studies have shown that differing ratios of n–6 to n–3 fatty acids alter the synthesis of prostaglandin and insulin-like growth factor I ( 2 ), that high levels of n–6 fatty[web.archive.org] Osteoporos Int 1997 ; 7 : 533 – 8 . 59 Protein supplements increase serum insulin-like growth factor-I levels and attenuate proximal femur bone loss in patients with recent[doi.org]

  • Escherichia Coli

    Joly JC, Leung WS, Swartz JR (1998) Overexpression of Escherichia coli oxidoreductases increases recombinant insulin-like growth factor-I accumulation.[doi.org]

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