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2,556 Possible Causes for Insulin Resistance

  • Endocrine Dysfunction

    The pathogenesis of diabetes is still relatively unclear, but the main mechanisms include the loss of insulin secretory capacity and insulin resistance secondary to liver[ncbi.nlm.nih.gov] Tsuneki H, Tokai E, Nakamura Y, “Hypothalamic orexin prevents hepatic insulin resistance via daily bidirectional regulation of autonomic nervous system in mice,” Diabetes[sleepdisorders.sleepfoundation.org] Women who have insulin resistance are at particular risk.[empoweryourhealth.org]

  • Acromegaly

    After therapy, homeostasis model assessment of insulin resistance, fasting insulin level, and insulin AUC decreased despite an increase in IHL and abdominal and thigh adipose[ncbi.nlm.nih.gov] Insulin resistance was calculated with homeostasis model assessment (HOMA).[ncbi.nlm.nih.gov] Abstract Secondary diabetes mellitus is known to occur in acromegaly due to insulin resistance caused by growth hormone excess.[ncbi.nlm.nih.gov]

  • Sunburn

    Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr . 2004; 79 (5): 820–825. [ PubMed ] [ Google Scholar ] 224.[ncbi.nlm.nih.gov] Hypovitaminosis D is associated with insulin resistance and beta cell dysfunction. Am J Clin Nutr . 2004 ;79(5): 820 –825. Crossref , Medline , Google Scholar 224.[doi.org]

  • Dementia

    Treating conditions such as insulin resistance, metabolic disorders, and vitamin deficiencies may reduce or eliminate symptoms of dementia.[helpguide.org] Obesity, insulin resistance and diabetes — a worldwide epidemic. Br J Nutr 2000 ;83: Suppl 1 : S5 - 8 28. Kövari E, Herrmann FR, Bouras C, Gold G.[nejm.org]

  • Osteoporosis

    Chonchol M, Scragg R (2007) 25-Hydroxyvitamin D, insulin resistance, and kidney function in the Third National Health and Nutrition Examination Survey.[doi.org] Forouhi NG, Luan J, Cooper A, Boucher BJ, Wareham NJ (2008) Baseline serum 25-hydroxy vitamin D is predictive of future glycemic status and insulin resistance: the Medical[doi.org] Liu E, Meigs JB, Pittas AG, McKeown NM, Economos CD, Booth SL, Jacques PF (2009) Plasma 25-hydroxyvitamin D is associated with markers of the insulin resistant phenotype in[doi.org]

  • Familial Partial Lipodystrophy

    The findings in FPLD indicate that defective structure of the nuclear envelope produces a phenotype of insulin resistance.[ncbi.nlm.nih.gov] In both groups, adiponectin levels were inversely correlated with body fat mass (controls, r -0.44, p 0.036; FDLP, r -0.67, p 0.025), insulin resistance (controls, r -0.62[ncbi.nlm.nih.gov] resistance.[ncbi.nlm.nih.gov]

  • Polycystic Ovary Syndrome

    Affected women have marked insulin resistance, independent of obesity.[ncbi.nlm.nih.gov] All patients received an insulin tolerance test to assess insulin resistance.[ncbi.nlm.nih.gov] resistance (fasting insulin   10 mIU/L).[ncbi.nlm.nih.gov]

  • Generalized Lipodystrophy

    insulin receptors exists and contributes to insulin resistance in the patient.[ncbi.nlm.nih.gov] Studies on insulin receptors of circulating mononuclear leucocytes indicated that insulin-resistant diabetes combined with congenital generalized lipodystrophy may be due[ncbi.nlm.nih.gov] Insulin resistance and insulin secretion were estimated using the homeostasis model assessment for insulin resistance and the insulinogenic index, respectively.[ncbi.nlm.nih.gov]

  • Lipodystrophy

    Patients with PLL had poor metabolic control and marked insulin resistance compared to subjects with type 2 diabetes.[ncbi.nlm.nih.gov] The metabolic abnormalities associated with lipodystrophy include insulin resistance, hypertriglyceridemia, and hepatic steatosis.[ncbi.nlm.nih.gov] She presented no severe metabolic complications, neither signs of insulin resistance.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus Type 2

    […] secretion and (b) peripheral insulin resistance resulting in a decrease in the metabolic responses to insulin.[ncbi.nlm.nih.gov] Initially, enhanced insulin secretion can compensate for the insulin resistance but early phase insulin secretion is impaired.[ncbi.nlm.nih.gov] Left ventricular dysfunction in Klinefelter syndrome is associated to insulin resistance, abdominal adiposity and hypogonadism . Clin. Endocrinol.[dx.doi.org]

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