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271 Possible Causes for Insulin Resistance, Onset at Age 5-10 Years

  • Diabetes Mellitus Type 2

    Epidemiology Type 1 : 5% of all patients with diabetes Childhood onset ; : typically 20 years but can occur at any age; peaks at age 4–6 years and 10–14 years Highest prevalence[amboss.com] […] secretion and (b) peripheral insulin resistance resulting in a decrease in the metabolic responses to insulin.[ncbi.nlm.nih.gov] Initially, enhanced insulin secretion can compensate for the insulin resistance but early phase insulin secretion is impaired.[ncbi.nlm.nih.gov]

  • Diabetes Mellitus

    Maternal history of diabetes or GDM during the child's gestation Age of initiation: age 10 years or at onset of puberty, if puberty occurs at a younger age Frequency: every[omicsonline.org] IR was determined using homeostasis model assessment of insulin resistance (HOMA-IR).[ncbi.nlm.nih.gov] Insulin resistance was assessed by the homeostasis model assessment for insulin resistance (HOMA-IR) and Matsuda insulin sensitivity index (Matsuda ISI).[ncbi.nlm.nih.gov]

  • Growth Hormone Deficiency

    Typical age of onset is between 5 and 10 years. [6] Tinea capitis accounts for up to 92.5% of dermatophytoses in children younger than 10 years.[emedicine.medscape.com] A1c, homeostasis model assessment estimate of insulin resistance, quantitative insulin sensitivity check index, insulin sensitivity index Matsuda, insulin-like growth factor-I[ncbi.nlm.nih.gov] Moreover, GH administration has no significant effects on increased insulin resistance and no adversely effect on glucose homeostasis.[ncbi.nlm.nih.gov]

  • Hypertension

    In general, all patients with young onset-age (  40-50 years) or resistant hypertension should be screened for secondary forms.[ncbi.nlm.nih.gov] DC and DRs correlate negatively with blood glucose and insulin resistance index.[ncbi.nlm.nih.gov] Deibert DC, DeFronzo RA: Epinephrine-induced insulin resistance in man. J Clin Invest 1980, 65: 717–721. PubMed CrossRef Google Scholar 34.[doi.org]

  • Acne Vulgaris

    5 40 years Genetic background , long course, polygenic , polygenic Age of onset circa 10 years circa 1 year Spontaneous remission 80% (3rd decade) 80% (2nd–3rd decade) Recurrences[ncbi.nlm.nih.gov] Role of insulin resistance and diet in acne.[doi.org] resistance.[ncbi.nlm.nih.gov]

  • Maternal Diabetes Syndrome

    C 2 : Duration 10-19 years. Class D: D 1 : Onset before 10 years of age. D 2 : Duration 10 years. D 3 : Calcification of vessels of the leg (macrovascular disease).[utmb.edu] We assessed insulin resistance on the basis of fasting insulin and glucose levels, using 2 methods.[pediatrics.aappublications.org] Normally, the pancreas is able to make additional insulin to overcome insulin resistance, but when the production of insulin is not enough to overcome the effect of the placental[stanfordchildrens.org]

  • Confluent and Reticulated Papillomatosis

    The mean patient age at onset varies from 18.5-21 years, with a range of 5-63 years.[emedicine.medscape.com] resistance .[dermnetnz.org] Similarly, the average patient age at onset is 17.1 years in Japan, with a range of 3-30 years.[emedicine.medscape.com]

  • Menopause Ovarian Disorder

    […] before age 18 years ( 10 ).[acog.org] Insulin resistance was derived using the Homeostasis Model Assessment method (HOMA-IR) from fasting measures of serum insulin and plasma glucose.[endocrine-abstracts.org] The basic problem seems to be that the body becomes resistant to its own insulin, a situation called insulin resistance (IR).[hormonehelpny.com]

  • Alstrom Syndrome

    Subcapsular cataracts were present in 52 patients (32%; age range, 10-44 years).[jamanetwork.com] resistance.[ncbi.nlm.nih.gov] Alström syndrome: A rare association of retinitis pigmentosa with insulin resistance syndrome.[ijem.in]

  • SHORT Syndrome

    Growth velocity 5 cm (2 in) per year No onset of puberty by 14 years of age for boys or 13 years of age for girls Projected height more than 2 standard deviations (10 cm[aafp.org] At 16 1/2 years, the diagnosis of diabetes mellitus secondary to severe insulin resistance was made by intravenous insulin challenge.[ncbi.nlm.nih.gov] We report the case of a 13-year-old boy with SHORT syndrome, including lipoatrophy and insulin resistance, who developed diabetes mellitus while receiving growth hormone therapy[ncbi.nlm.nih.gov]

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